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    Enobosarm

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    DIGITAL CONTENT

    PharmaCompass
    Xls

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    2D Structure
    Also known as: Ostarine, 841205-47-8, Gtx-024, Mk-2866, Enobosarm [usan], Mk-2866 (gtx-024)
    Molecular Formula
    C19H14F3N3O3
    Molecular Weight
    389.3  g/mol
    InChI Key
    JNGVJMBLXIUVRD-SFHVURJKSA-N
    FDA UNII
    O3571H3R8N
    Enobosarm is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostate growth, and muscle growth and strength. Mimicking testosterone's action, this agent may increase lean body mass, thereby ameliorating muscle wasting in the hypermetabolic state of cancer cachexia.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
    2.1.2 InChI
    InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m0/s1
    2.1.3 InChI Key
    JNGVJMBLXIUVRD-SFHVURJKSA-N
    2.1.4 Canonical SMILES
    CC(COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
    2.1.5 Isomeric SMILES
    C[C@](COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
    2.2 Other Identifiers
    2.2.1 UNII
    O3571H3R8N
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. (2s)-3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide

    2. Gtx 024

    3. Gtx-024

    4. Mk 2866

    5. Mk-2866

    6. Mk2866

    7. Ostarine

    2.3.2 Depositor-Supplied Synonyms

    1. Ostarine

    2. 841205-47-8

    3. Gtx-024

    4. Mk-2866

    5. Enobosarm [usan]

    6. Mk-2866 (gtx-024)

    7. 1202044-20-9

    8. Ostarine (mk2866)

    9. Ostarine(mk-2866)

    10. (2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

    11. (s)-n-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide

    12. Mk 2866

    13. O3571h3r8n

    14. Enobosarm (usan)

    15. Propanamide, 3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-, (2s)-

    16. Mk2866

    17. ((2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide)

    18. Enobosarm [usan:inn]

    19. Gtx 024

    20. Unii-o3571h3r8n

    21. Ostarine-d4

    22. (s)-ostarine

    23. (2s)-3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide

    24. Enobosarm [inn]

    25. Ostarine(mk-2286)

    26. Enobosarm [who-dd]

    27. Mls006010739

    28. Sarm S-22

    29. Schembl109069

    30. Not For Sale-patented"

    31. Chembl1738889

    32. Dtxsid30233006

    33. Ex-a638

    34. Hms3654e16

    35. Amy38131

    36. Bcp02391

    37. Bcp28483

    38. Bdbm50529668

    39. S1174

    40. Zinc35793636

    41. Akos005266718

    42. Ccg-268514

    43. Cs-0562

    44. Db12078

    45. Ex-8408

    46. Sb16683

    47. Ncgc00346499-01

    48. Ac-30221

    49. Hy-13273

    50. Smr004701698

    51. Sw219159-1

    52. Ostarine(mk2286); 1202044-20-9

    53. D10221

    54. H12015

    55. A864177

    56. Q5379258

    57. 1235370-13-4

    58. Mk-2866(d4);mk2866(d4);gtx-024(d4);gtx024;(s)-n-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide-d4

    59. Mk-2866; Gtx024;((2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide)

    60. Propanamide, 3-?(4-?cyanophenoxy)?-?n-?[4-?cyano-?3-?(trifluoromethyl)?phenyl]?-?2-?hydroxy-?2-?methyl-?, (2s)?-

    61. Rlj

    2.4 Create Date
    2006-10-26
    3 Chemical and Physical Properties
    Molecular Weight 389.3 g/mol
    Molecular Formula C19H14F3N3O3
    XLogP32.7
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count5
    Exact Mass389.09872580 g/mol
    Monoisotopic Mass389.09872580 g/mol
    Topological Polar Surface Area106 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity658
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1