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Technical details about Enobosarm, learn more about the structure, uses, toxicity, action, side effects and more

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2D Structure
1. Also known as: Ostarine, 841205-47-8, Gtx-024, Mk-2866, Enobosarm [usan], Mk-2866 (gtx-024)
Molecular Formula
C19H14F3N3O3
Molecular Weight
389.3  g/mol
InChI Key
JNGVJMBLXIUVRD-SFHVURJKSA-N
FDA UNII
O3571H3R8N

Enobosarm is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostate growth, and muscle growth and strength. Mimicking testosterone's action, this agent may increase lean body mass, thereby ameliorating muscle wasting in the hypermetabolic state of cancer cachexia.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
2.1.2 InChI
InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m0/s1
2.1.3 InChI Key
JNGVJMBLXIUVRD-SFHVURJKSA-N
2.1.4 Canonical SMILES
CC(COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
2.1.5 Isomeric SMILES
C[C@](COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
2.2 Other Identifiers
2.2.1 UNII
O3571H3R8N
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (2s)-3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide

2. Gtx 024

3. Gtx-024

4. Mk 2866

5. Mk-2866

6. Mk2866

7. Ostarine

2.3.2 Depositor-Supplied Synonyms

1. Ostarine

2. 841205-47-8

3. Gtx-024

4. Mk-2866

5. Enobosarm [usan]

6. Mk-2866 (gtx-024)

7. 1202044-20-9

8. Ostarine (mk2866)

9. Ostarine(mk-2866)

10. (2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

11. (s)-n-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide

12. Mk 2866

13. O3571h3r8n

14. Enobosarm (usan)

15. Propanamide, 3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-, (2s)-

16. Mk2866

17. ((2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide)

18. Enobosarm [usan:inn]

19. Gtx 024

20. Unii-o3571h3r8n

21. Ostarine-d4

22. (s)-ostarine

23. (2s)-3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide

24. Enobosarm [inn]

25. Ostarine(mk-2286)

26. Enobosarm [who-dd]

27. Mls006010739

28. Sarm S-22

29. Schembl109069

30. Not For Sale-patented"

31. Chembl1738889

32. Dtxsid30233006

33. Ex-a638

34. Hms3654e16

35. Amy38131

36. Bcp02391

37. Bcp28483

38. Bdbm50529668

39. S1174

40. Zinc35793636

41. Akos005266718

42. Ccg-268514

43. Cs-0562

44. Db12078

45. Ex-8408

46. Sb16683

47. Ncgc00346499-01

48. Ac-30221

49. Hy-13273

50. Smr004701698

51. Sw219159-1

52. Ostarine(mk2286); 1202044-20-9

53. D10221

54. H12015

55. A864177

56. Q5379258

57. 1235370-13-4

58. Mk-2866(d4);mk2866(d4);gtx-024(d4);gtx024;(s)-n-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide-d4

59. Mk-2866; Gtx024;((2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide)

60. Propanamide, 3-?(4-?cyanophenoxy)?-?n-?[4-?cyano-?3-?(trifluoromethyl)?phenyl]?-?2-?hydroxy-?2-?methyl-?, (2s)?-

61. Rlj

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 389.3 g/mol
Molecular Formula C19H14F3N3O3
XLogP32.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass389.09872580 g/mol
Monoisotopic Mass389.09872580 g/mol
Topological Polar Surface Area106 Ų
Heavy Atom Count28
Formal Charge0
Complexity658
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
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