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    ethylenediamine sulfate

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    DIGITAL CONTENT

    MARKET PLACE

    PharmaCompass
    $ API Ref.Price (USD/KG) : 70Xls

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    2D Structure
    Also known as: 5700-49-2, Jodethamine, Ethane-1,2-diamine dihydroiodide, Ethanediamine dihydroiodide, Hydrodine, Eddi
    Molecular Formula
    C2H10I2N2
    Molecular Weight
    315.92  g/mol
    InChI Key
    IWNWLPUNKAYUAW-UHFFFAOYSA-N
    FDA UNII
    721M52NQ5L
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    ethane-1,2-diamine;dihydroiodide
    2.1.2 InChI
    InChI=1S/C2H8N2.2HI/c3-1-2-4;;/h1-4H2;2*1H
    2.1.3 InChI Key
    IWNWLPUNKAYUAW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C(CN)N.I.I
    2.2 Other Identifiers
    2.2.1 UNII
    721M52NQ5L
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 1,2-diaminoethane

    2. 1,2-ethanediamine

    3. Edamine

    4. Ethane-1,2-diamine

    5. Ethyl Diamine

    6. Ethylenediamine

    7. Ethylenediamine (1:1) Sulfate

    8. Ethylenediamine (1:1) Sulfite

    9. Ethylenediamine Conjugate Acid

    10. Ethylenediamine Dihydrobromide

    11. Ethylenediamine Dihydrochloride

    12. Ethylenediamine Dihydrogen Iodide

    13. Ethylenediamine Dinitrate

    14. Ethylenediamine Hydrochloride

    15. Ethylenediamine Monohydrochloride

    16. Ethylenediamine Phosphate

    17. Ethylenediamine Sulfate

    18. Ethylenediamine, 3h-labeled Cpd

    2.3.2 Depositor-Supplied Synonyms

    1. 5700-49-2

    2. Jodethamine

    3. Ethane-1,2-diamine Dihydroiodide

    4. Ethanediamine Dihydroiodide

    5. Hydrodine

    6. Eddi

    7. Ethylenediamine Dihydriodide

    8. Orgadine

    9. Ethylenediammonium Diiodide

    10. Ethane-1,2-diamine;dihydroiodide

    11. Ethylendiamine Dihydroiodide

    12. 1,2-ethanediamine Dihydriodide

    13. 1,2-ethanediamine Dihydroiodide

    14. Chebi:81719

    15. 721m52nq5l

    16. Ethane-1,2-diammonium Iodide

    17. Hiamine

    18. Iomide

    19. Hydriodide-boot

    20. Iod-ethamine

    21. Hy-odide

    22. Hi-boot

    23. Hydriodide-o-dide

    24. Hi-o-dide

    25. 1,2-ethanediamine, Dihydriodide

    26. Unii-721m52nq5l

    27. Hsdb 440

    28. Ethane-1,2-diamine,dihydroiodide

    29. Einecs 227-186-8

    30. Hoffman Bonded E-d-d Iodine Compound

    31. Whitmoyer Ethylene Diamine Dihydriodide

    32. Dsstox_cid_24570

    33. Dsstox_rid_80319

    34. Dsstox_gsid_44570

    35. Schembl1007637

    36. Chembl3182879

    37. Dtxsid5044570

    38. 1,2-diaminoethane, Dihydroiodide

    39. Tox21_302266

    40. Mfcd00035535

    41. Akos024334047

    42. 1,2-ethanediamine, Hydriodide (1:2)

    43. Ethane-1,2-diammonium Iodide, >=98%

    44. Ncgc00255744-01

    45. As-60979

    46. Cas-5700-49-2

    47. Db-052998

    48. Ethylenediamine Dihydroiodide [hsdb]

    49. E1222

    50. Ft-0635813

    51. C18382

    52. T72638

    53. 700e492

    54. Q3027890

    55. W-105492

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 315.92 g/mol
    Molecular Formula C2H10I2N2
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count1
    Exact Mass315.89334 g/mol
    Monoisotopic Mass315.89334 g/mol
    Topological Polar Surface Area52 Ų
    Heavy Atom Count6
    Formal Charge0
    Complexity6
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Therapeutic Uses

    VET: ...ETHYLENEDIAMINE DIHYDROIODIDE (EDDI), IS FED TO CATTLE TO PREVENT OR TREAT VARIOUS AILMENTS SUCH AS FOOT ROT, MILD RESP CONDITIONS, ACTINOMYCOSIS, MASTITIS, OTHER CHRONIC INFECTIONS, & IODINE DEFICIENCY.

    Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284

    VET: EXPECTORANT & ANTIINFLAMMATORY AGENT

    Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284

    (VET): FEED ADDITIVE

    Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 208

    4.2 Drug Warning

    VET: .../EDDI INTAKE/ SHOULD BE CURTAILED PRIOR TO CALVING, SHIPPING, VACCINATION, OR OTHER STRESSFUL SITUATIONS BECAUSE STRESS IS MAJOR FACTOR IN DEVELOPMENT OF EDDI-RELATED INFECTIONS.

    Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284

    MORE RESEARCH IS NEEDED TO CHARACTERIZE DISEASE-ENHANCING ACTIONS OF EDDI REPORTED BY PRACTITIONERS & CATTLEMEN.

    Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 01284

    5 Pharmacology and Biochemistry
    5.1 Absorption, Distribution and Excretion

    IN CATTLE NORMAL TOTAL SERUM IODINE CONCN RANGES FROM 5.6 TO 14 UG/100 ML... IN SHEEP NORMAL TOTAL SERUM IODINE CONCN IS ABOUT 2.3-4.6 UG/100 ML... IN CASES OF EDDI-INDUCED IODISM &...INFECTION...TOTAL SERUM IODINE CONCN.../REPORTED/ 10-100 OR MORE TIMES NORMAL.

    Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1285

    IODIDES ARE READILY EXCRETED IN MILK /OF CATTLE/. ... IODIDES...ALSO SECRETED BY GLANDULAR CELLS IN RESP TRACT... SALIVARY & LACRIMAL GLANDS ALSO SECRETE IODIDES.

    Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284

    5.2 Mechanism of Action

    ...REFLECTIONS OF PROSECRETORY ACTIONS OF IODIDE...SUSCEPTIBILITY OR PREDISPOSITION...TO MICROBIAL INFECTIONS /& FEVER/...ATTRIBUTED TO POSSIBLE ANTIINFLAMMATORY ACTION...ABILITY OF IODINE TO UNCOUPLE OXIDATIVE PHOSPHORYLATION.

    Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284