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1. (3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic Acid C-(tetrahydro-3-furanyl) Ester
2. Fos-amprenavir
3. Fosamprenavir
4. Fosamprenavir Sodium
5. Gw 433908
6. Gw 433908a
7. Gw 433908g
8. Gw 908
9. Gw-433908
10. Gw-433908a
11. Gw-433908g
12. Gw-908
13. Gw433908
14. Gw433908g
15. Lexiva
16. Telzir
17. Vx 175
18. Vx-175
1. 226700-81-8
2. Fosamprenavir Calcium Salt
3. Lexiva
4. Telzir
5. Fosamprenavir (calcium Salt)
6. Fosamprenavir Calcium [usan]
7. Gw433908g
8. Gw 433908g
9. Gw-433908g
10. Id1gu2627n
11. Lexiva (tn)
12. Calcium;[(2r,3s)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3s)-oxolan-3-yl]oxycarbonylamino]-4-phenylbutan-2-yl] Phosphate
13. Carbamic Acid, ((1s,2r)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3s)-tetrahydro-3-furanyl) Ester, Calcium Salt (1:1)
14. Fosamprenavir Calcium (usan)
15. Amprenavir Phosphate Calcium
16. Calcium (2r,3s)-1-(4-amino-n-isobutylphenylsulfonamido)-4-phenyl-3-(((((s)-tetrahydrofuran-3-yl)oxy)carbonyl)amino)butan-2-yl Phosphate
17. Unii-id1gu2627n
18. Telzir (tn)
19. Ncgc00168771-01
20. Dsstox_cid_26777
21. Dsstox_rid_81896
22. Dsstox_gsid_46777
23. ((3s)oxolan-3-yloxy)-n-((1s,2r)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-benzyl-2-(phosphonooxy)propyl)carboxamide Calcium Salt
24. Mls006012033
25. Schembl1649283
26. Chembl1200734
27. Dtxsid0046777
28. Amy6787
29. Tox21_112632
30. Fosamprenavir Calcium [mart.]
31. Akos015950832
32. Fosamprenavir Calcium [who-dd]
33. Cs-1411
34. Fosamprenavir Calcium Salt [mi]
35. Fosamprenavir Calcium [ema Epar]
36. Fosamprenavir Calcium, >=98% (hplc)
37. (3s)-tetrahydro-3-furyl ((alphas)-alpha-((1r)-1-hydroxy-2-(n(sup 1)-isobutylsulfanilamido)ethyl)phenethyl)carbamate, Calcium Phosphate (ester) (1:1)
38. As-82030
39. Carbamic Acid, ((1s,2r)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3s)-tetrahydro-3-furanyl) Ester, Calcium Salt
40. Hy-17431
41. Smr004703563
42. Fosamprenavir Calcium [orange Book]
43. Cas-226700-81-8
44. C74170
45. D03835
46. Q27280661
47. (3s)-tetrahydro-3-furyl ((.alpha.s)-.alpha.-((1r)-1-hydroxy-2-(n(sup 1)-isobutylsulfanilamido)ethyl)phenethyl)carbamate, Calcium Phosphate (ester) (1:1)
48. (3s)-tetrahydro-3-furyl ((.alpha.s)-.alpha.-((1r)-1-hydroxy-2-(n1-isobutylsulfanilamido)ethyl)phenethyl)carbamate, Calcium Phosphate (ester) (1:1)
49. Calcium(2r,3s)-1-(4-amino-n-isobutylphenylsulfonamido)-4-phenyl-3-(((((s)-tetrahydrofuran-3-yl)oxy)carbonyl)amino)butan-2-ylphosphate
Molecular Weight | 623.7 g/mol |
---|---|
Molecular Formula | C25H34CaN3O9PS |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 11 |
Rotatable Bond Count | 13 |
Exact Mass | 623.1379287 g/mol |
Monoisotopic Mass | 623.1379287 g/mol |
Topological Polar Surface Area | 192 Ų |
Heavy Atom Count | 40 |
Formal Charge | 0 |
Complexity | 901 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 3 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 2 |
1 of 2 | |
---|---|
Drug Name | Lexiva |
PubMed Health | Fosamprenavir (By mouth) |
Drug Classes | Antiretroviral Agent |
Drug Label | LEXIVA (fosamprenavir calcium) is a prodrug of amprenavir, an inhibitor of HIV protease. The chemical name of fosamprenavir calcium is (3S)-tetrahydrofuran-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl](isobutyl)amino]-1-benzyl-2-(phosphonooxy) propylcar... |
Active Ingredient | Fosamprenavir calcium |
Dosage Form | Tablet; Suspension |
Route | Oral |
Strength | eq 700mg base; eq 50mg base/ml |
Market Status | Prescription |
Company | Viiv Hlthcare |
2 of 2 | |
---|---|
Drug Name | Lexiva |
PubMed Health | Fosamprenavir (By mouth) |
Drug Classes | Antiretroviral Agent |
Drug Label | LEXIVA (fosamprenavir calcium) is a prodrug of amprenavir, an inhibitor of HIV protease. The chemical name of fosamprenavir calcium is (3S)-tetrahydrofuran-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl](isobutyl)amino]-1-benzyl-2-(phosphonooxy) propylcar... |
Active Ingredient | Fosamprenavir calcium |
Dosage Form | Tablet; Suspension |
Route | Oral |
Strength | eq 700mg base; eq 50mg base/ml |
Market Status | Prescription |
Company | Viiv Hlthcare |
Telzir in combination with low-dose ritonavir is indicated for the treatment of human-immunodeficiency-virus-type-1-infected adults, adolescents and children of six years and above in combination with other antiretroviral medicinal products.
In moderately antiretroviral-experienced adults, Telzir in combination with low-dose ritonavir has not been shown to be as effective as lopinavir / ritonavir. No comparative studies have been undertaken in children or adolescents.
In heavily pretreated patients, the use of Telzir in combination with low-dose ritonavir has not been sufficiently studied.
In protease-inhibitor-experienced patients, the choice of Telzir should be based on individual viral resistance testing and treatment history.
HIV Protease Inhibitors
Inhibitors of HIV PROTEASE, an enzyme required for production of proteins needed for viral assembly. (See all compounds classified as HIV Protease Inhibitors.)
Anti-HIV Agents
Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS. (See all compounds classified as Anti-HIV Agents.)
J05AE07