1. 1-((3s)-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1h-pyrazolo(3, 4-d) Pyrimidin-1-yl)-1-pyrrolidinyl)-2-propen-1-one
2. Tas-120
1. Tas-120
2. 1448169-71-8
3. Fgfr-in-1
4. Tas120
5. Futibatinib [usan]
6. 4b93mge4al
7. Tas 120
8. (s)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one
9. 1-[(3s)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-one
10. 1-[(3s)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
11. 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one
12. 2-propen-1-one, 1-((3s)-3-(4-amino-3-(2-(3,5-dimethoxyphenyl)ethynyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-pyrrolidinyl)-
13. Unii-4b93mge4al
14. Lytgobi
15. Futibatinib [inn]
16. Futibatinib [jan]
17. Futibatinib [who-dd]
18. Futibatinib (jan/usan/inn)
19. Gtpl9786
20. Chembl3701238
21. Schembl15345470
22. Tas 120 [who-dd]
23. Bdbm161389
24. Amy16930
25. Bcp17213
26. Ex-a1862
27. Nsc813488
28. Who 10879
29. Zinc207800318
30. Cs-6031
31. Db15149
32. Example 2 [wo2013108809]
33. Nsc-813488
34. Ac-35460
35. Bs-15425
36. Hy-100818
37. D11725
38. D77976
39. Us9108973, 2
40. 1814961-20-0
Molecular Weight | 418.4 g/mol |
---|---|
Molecular Formula | C22H22N6O3 |
XLogP3 | 2 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 7 |
Rotatable Bond Count | 6 |
Exact Mass | 418.17533859 g/mol |
Monoisotopic Mass | 418.17533859 g/mol |
Topological Polar Surface Area | 108 Ų |
Heavy Atom Count | 31 |
Formal Charge | 0 |
Complexity | 723 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 1 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Treatment of cholangiocarcinoma
Antineoplastic Agents
Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)
L - Antineoplastic and immunomodulating agents
L01 - Antineoplastic agents
L01E - Protein kinase inhibitors
L01EN - Fibroblast growth factor receptor (fgfr) tyrosine kinase inhibitors
L01EN04 - Futibatinib
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