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    Technical details about Gallopamil, learn more about the structure, uses, toxicity, action, side effects and more

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    Gallopamil

    APIs // Active Pharmaceutical Ingredients

    DOSSIERs // Finished Dosage Forms

    GLOBAL SALES INFORMATION

    PharmaCompass

    Symbiotec: Global API manufacturer, specializing in Cortico-Steroids & Steroid-Hormone APIs.

    Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

    2D Structure
    1. Also known as: 16662-46-7, Procorum, Gallopamil hcl, Methoxyverapamil hydrochloride, Gallopamil (hydrochloride), 5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile hydrochloride
    Molecular Formula
    C28H41ClN2O5
    Molecular Weight
    521.1  g/mol
    InChI Key
    OKCRIUNHEQSXFD-UHFFFAOYSA-N
    FDA UNII
    VT4VR32A0T
    Coronary vasodilator that is an analog of iproveratril (VERAPAMIL) with one more methoxy group on the benzene ring.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile;hydrochloride
    2.1.2 InChI
    InChI=1S/C28H40N2O5.ClH/c1-20(2)28(19-29,22-17-25(33-6)27(35-8)26(18-22)34-7)13-9-14-30(3)15-12-21-10-11-23(31-4)24(16-21)32-5;/h10-11,16-18,20H,9,12-15H2,1-8H3;1H
    2.1.3 InChI Key
    OKCRIUNHEQSXFD-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C(=C2)OC)OC)OC.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    VT4VR32A0T
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. D 600

    2. D-600

    3. D600

    4. Elgiprona

    5. Gallobeta

    6. Gallopamil

    7. Gallopamil Von Ct

    8. Hydrochloride, Gallopamil

    9. Methoxyverapamil

    10. Prebet

    11. Procorum

    2.3.2 Depositor-Supplied Synonyms

    1. 16662-46-7

    2. Procorum

    3. Gallopamil Hcl

    4. Methoxyverapamil Hydrochloride

    5. Gallopamil (hydrochloride)

    6. 5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile Hydrochloride

    7. (+/-)-methoxyverapamil Hydrochloride

    8. Vt4vr32a0t

    9. Mls000069359

    10. Methoxyverapamil (hydrochloride)

    11. Nsc-274966

    12. Smr000058477

    13. [3-cyano-3-(3,4,5-trimethoxyphenyl)hex-6-yl]-(5,6-dimethoxyphenethyl)methylammonium Chloride

    14. Dsstox_cid_27844

    15. Dsstox_rid_82597

    16. Dsstox_gsid_47858

    17. 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile;hydrochloride

    18. 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile;hydron;chloride

    19. Gallopamil Hydrochloride (jan)

    20. Gallopamil Hydrochloride [jan]

    21. (3-cyano-3-(3,4,5-trimethoxyphenyl)hex-6-yl)-(5,6-dimethoxyphenethyl)methylammonium Chloride

    22. 5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile Hcl

    23. Cas-16662-46-7

    24. D 600 Hydrochloride

    25. Ncgc00015686-05

    26. Einecs 240-704-7

    27. Unii-vt4vr32a0t

    28. Nsc 274966

    29. D600; Gallopamil

    30. Opera_id_1611

    31. D-600 Hydrochloride

    32. (+/-)-methoxyverapamil Hcl

    33. Benzeneacetonitrile, Alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4,5-trimethoxy-alpha-(1-methylethyl)-, Monohydrochloride

    34. Schembl194931

    35. Chembl1256940

    36. Dtxsid2047858

    37. (?)-methoxyverapamil Hydrochloride

    38. (y)-methoxyverapamil Hydrochloride

    39. Tox21_110196

    40. Tox21_500778

    41. Gallopamil Hydrochloride [mi]

    42. Hy-14276a

    43. Mfcd00058000

    44. Nsc274966

    45. Akos015994622

    46. Tox21_110196_1

    47. Ccg-222082

    48. Hs-0066

    49. Lp00778

    50. Gallopamil Hydrochloride [mart.]

    51. Gallopamil Hydrochloride [who-dd]

    52. Ncgc00015686-11

    53. Ncgc00094115-01

    54. Ncgc00261463-01

    55. Lu-30029

    56. Cs-0109891

    57. Eu-0100778

    58. Ft-0727258

    59. Ft-0772263

    60. (+/-)-methoxyverapamil Hydrochloride, >=98%

    61. D01969

    62. I11594

    63. M 5644

    64. Sr-01000000018

    65. J-010303

    66. Sr-01000000018-2

    67. Q27095539

    68. ( Inverted Question Mark)-methoxyverapamil Hydrochloride

    69. (+/-)-alpha-[3-[(2-(3,4-dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-alpha-(1-methylethyl)benzeneacetonitrile Hydrochloride

    70. .alpha.-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4,5-trimethoxy-.alpha.-(1-methylethyl)benzeneacetonitrile Hydrochloride

    71. .alpha.-isopropyl-.alpha.-((n-methyl-n-homoveratryl)-.gamma.-aminopropyl)-3,4,5-trimethoxyphenylacetonitrile Hydrochloride

    72. 5-(3,4-dimethoxyphenethyl) Methylamino-2-isopropyl-2-(3,4,5-trimethoxyphenyl)-valeronitrile Hydrochloride

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 521.1 g/mol
    Molecular Formula C28H41ClN2O5
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count14
    Exact Mass520.2704001 g/mol
    Monoisotopic Mass520.2704001 g/mol
    Topological Polar Surface Area73.2 Ų
    Heavy Atom Count36
    Formal Charge0
    Complexity639
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Calcium Channel Blockers

    A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

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