Gentamicin Sulfate

ACCESS ALL DATA, CHEMISTRY

ACTIVE PHARMA INGREDIENTS

20 API Suppliers, 13 USDMF, 2 CEP/COS, 3 JDMF, 2 KDMF, 10 NDC API, 3 VMF, 7 Listed Suppliers, $ API Reference Price

DEVELOPMENTS

9 Drugs in Development

9 Drugs in Development

FINISHED DOSAGE FORMULATIONS

316 FDF Dossiers, 123 FDA Orange Book, 85 Europe, 19 Canada, 1 Australia, 37 South Africa, 51 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SUSPENSION/DROPS;OPHTHALMIC - EQ 0.3% BASE;1%, OINTMENT;OPHTHALMIC - EQ 0.3% BASE;0.6%

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 2 SPI Pharma, 1 DKSH, 2 Gangwal Healthcare, 3 Nanjing Well Pharmaceutical, 5 Actylis, 6 BASF, 5 Corel Pharma Chem, 1 Curia, 2 Finar, 2 Gangwal Chemicals, 2 Ideal Cures Pvt Ltd, 3 Kerry, 3 Microlex e.U, 1 Novo Excipients, 11 Roquette, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Valens Pharmachem, 1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

17 Coating Systems & Additives, 12 Film Formers & Plasticizers, 8 Topical, 8 Parenteral, 7 Solubilizers, 7 Fillers, Diluents & Binders, 4 Taste Masking, 4 Controlled & Modified Release, 3 Lubricants & Glidants, 3 Thickeners and Stabilizers, 2 Direct Compression, 2 Chewable & Orodispersible Aids, 2 Emulsifying Agents, 1 Granulation, 1 Soft Gelatin, 1 Surfactant & Foaming Agents, 1 Co-Processed Excipients, 1 Disintegrants & Superdisintegrants, 1 API Stability Enhancers

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 23 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

89 Finished Drug Prices

89 Finished Drug Prices

MARKET PLACE

56 APIs, 12 FDF Dossiers

REF. STANDARDS & IMPURITIES

3 EDQM, 1 USP, 2 Others

ANALYTICAL

1 BioAnalytical Methods

1 BioAnalytical Methods

$ Xls

Filters

Also known as: Garamycin solution, Gentimicin sulfate solution, Gentamicin sulfate, 500x solution, Akos015895526, G0383

Molecular Formula

C₂₁H₄₅N₅O₁₁S

Molecular Weight

575.7 g/mol

InChI Key

NWQISSNHRDDWRM-UHFFFAOYSA-N

1 2D Structure

2D Structure

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid

2.1.2 InChI

InChI=1S/C21H43N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;(H2,1,2,3,4)

2.1.3 InChI Key

NWQISSNHRDDWRM-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.OS(=O)(=O)O

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Garamycin Solution

2. Gentimicin Sulfate Solution

3. Gentamicin Sulfate, 500x Solution

4. Akos015895526

5. G0383

2.3 Create Date

2009-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₄₅N₅O₁₁S
Molecular Weight	575.7 g/mol
Hydrogen Bond Donor Count	10
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	7
Exact Mass	575.28362844 g/mol
Monoisotopic Mass	575.28362844 g/mol
Topological Polar Surface Area	283 Å²
Heavy Atom Count	38
Formal Charge	0
Complexity	717
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	13
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Genoptic
PubMed Health	Gentamicin
Drug Classes	Antibacterial, Antibiotic
Active Ingredient	Gentamicin sulfate
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	eq 0.3% base
Market Status	Prescription
Company	Allergan

2 of 2
Drug Name	Genoptic
PubMed Health	Gentamicin
Drug Classes	Antibacterial, Antibiotic
Active Ingredient	Gentamicin sulfate
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	eq 0.3% base
Market Status	Prescription
Company	Allergan

Gentamicin Sulfate

Gentamicin Sulfate

ACCESS ALL DATA

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CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

20 API Suppliers

13 USDMF

2 CEP/COS

3 JDMF

2 KDMF

10 NDC API

3 VMF

7 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

9 Drugs in Development

FINISHED DOSAGE FORMULATIONS

316 FDF Dossiers

123 FDA Orange Book

85 Europe

19 Canada

1 Australia

37 South Africa

51 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SUSPENSION/DROPS;OPHTHALMIC - EQ 0.3% BASE;1%

OINTMENT;OPHTHALMIC - EQ 0.3% BASE;0.6%

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc

2 SPI Pharma

1 DKSH

2 Gangwal Healthcare

3 Nanjing Well Pharmaceutical

5 Actylis

6 BASF

5 Corel Pharma Chem

1 Curia

2 Finar

2 Gangwal Chemicals

2 Ideal Cures Pvt Ltd

3 Kerry

3 Microlex e.U

1 Novo Excipients

11 Roquette

1 Shijiazhuang Huaxu Pharmaceutical

1 Valens Pharmachem

1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

17 Coating Systems & Additives

12 Film Formers & Plasticizers

8 Topical

8 Parenteral

7 Solubilizers

7 Fillers, Diluents & Binders

4 Taste Masking

4 Controlled & Modified Release

3 Lubricants & Glidants

3 Thickeners and Stabilizers

2 Direct Compression

2 Chewable & Orodispersible Aids

2 Emulsifying Agents

1 Granulation

1 Soft Gelatin

1 Surfactant & Foaming Agents

1 Co-Processed Excipients

1 Disintegrants & Superdisintegrants

1 API Stability Enhancers

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow

23 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

89 Finished Drug Prices

MARKET PLACE

56 APIs

12 FDF Dossiers

REF. STANDARDS & IMPURITIES

3 EDQM

1 USP