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    Hydroxydopamine Hydrobromide

    ACTIVE PHARMA INGREDIENTS

    DIGITAL CONTENT

    PharmaCompass
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    2D Structure
    Also known as: 636-00-0, Oxidopamine hydrobromide, Oxidopamine (hydrobromide), 6-hydroxydopamine hbr, 6-ohda, 2,4,5-trihydroxyphenethylamine hydrobromide
    Molecular Formula
    C8H12BrNO3
    Molecular Weight
    250.09  g/mol
    InChI Key
    MLACDGUOKDOLGC-UHFFFAOYSA-N
    FDA UNII
    TWC1D4W0WB
    A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    5-(2-aminoethyl)benzene-1,2,4-triol;hydrobromide
    2.1.2 InChI
    InChI=1S/C8H11NO3.BrH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
    2.1.3 InChI Key
    MLACDGUOKDOLGC-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=C(C(=CC(=C1O)O)O)CCN.Br
    2.2 Other Identifiers
    2.2.1 UNII
    TWC1D4W0WB
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 6 Hydroxydopamine

    2. 6-hydroxydopamine

    3. 6-ohda

    4. Hydrobromide, Oxidopamine

    5. Hydrochloride, Oxidopamine

    6. Oxidopamine

    7. Oxidopamine Hydrobromide

    8. Oxidopamine Hydrochloride

    2.3.2 Depositor-Supplied Synonyms

    1. 636-00-0

    2. Oxidopamine Hydrobromide

    3. Oxidopamine (hydrobromide)

    4. 6-hydroxydopamine Hbr

    5. 6-ohda

    6. 2,4,5-trihydroxyphenethylamine Hydrobromide

    7. 5-(2-aminoethyl)benzene-1,2,4-triol Hydrobromide

    8. 6-ohda Hbr

    9. Mfcd00012894

    10. Twc1d4w0wb

    11. 2-(2,4,5-trihydroxyphenyl)ethylamine Hydrobromide

    12. 1,2,4-benzenetriol, 5-(2-aminoethyl)-, Hydrobromide

    13. 6-hydroxydopamine Hydrobromide;6-ohda Hydrobromide

    14. Nsc-238469

    15. 636-00-0 (hbr)

    16. 6-hydroxydopamine Hydrogen Bromide

    17. Mls002207128

    18. 2,5-dihydroxytyramine Hydrobromide

    19. Smr001306725

    20. Einecs 211-247-0

    21. Unii-twc1d4w0wb

    22. Nsc 238469

    23. 5-(2-aminoethyl)-4-hydroxypyrocatechol Hydrobromide

    24. 5-(2-aminoethyl)benzene-1,2,4-triol;hydrobromide

    25. 6-ohda Hydrobromide

    26. 6-hydroxydopamine.hydrobromide

    27. Schembl738049

    28. 4-chlorobenzenecarbaldehydeoxime

    29. Chembl1718398

    30. Hy-b1081a

    31. Dtxsid30212972

    32. Wln: Z2r Bq Dq Eq &eh

    33. Bcp25700

    34. Ex-a4152

    35. 6-hydroxydopamine Hydrobromide, 95%

    36. Nsc238469

    37. S5324

    38. Akos015916618

    39. Ccg-266959

    40. Cs-5966

    41. As-40064

    42. Sy102034

    43. Db-054509

    44. B7099

    45. Ft-0632700

    46. M01851

    47. 6-ohda Hydrobromide6-hydroxydopamine Hydrobromide

    48. A935047

    49. 1,4-benzenetriol, 5-(2-aminoethyl)-, Hydrobromide

    50. 5-(2-aminoethyl)-1,2,4-benzenetriol Hydrobromide

    51. 6-hydroxydopamine Hydrobromide, >=90% (hplc), Solid

    52. Q27290460

    53. 1,2,4-benzenetriol, 5-(2-aminoethyl)-, Hydrobromide (1:1)

    54. 6-ohda Hbr; 6 Ohda Hbr;oxidopamine Hydrobromide; 6-hydroxydopamine Hbr

    55. 6-hydroxydopamine Hydrobromide, Contains Ascorbic Acid As Stabilizer, >=98% (hplc)

    2.4 Create Date
    2005-07-19
    3 Chemical and Physical Properties
    Molecular Weight 250.09 g/mol
    Molecular Formula C8H12BrNO3
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count2
    Exact Mass249.00006 g/mol
    Monoisotopic Mass249.00006 g/mol
    Topological Polar Surface Area86.7 Ų
    Heavy Atom Count13
    Formal Charge0
    Complexity142
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Sympatholytics

    Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. (See all compounds classified as Sympatholytics.)

    Adrenergic Agents

    Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (See all compounds classified as Adrenergic Agents.)