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    Ingavirin

    ACTIVE PHARMA INGREDIENTS

    PharmaCompass
    Xls

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    2D Structure
    Also known as: 219694-63-0, Ingamine, Imidazolyl ethanamide pentandioic acid, Pentanedioic acid imidazolyl ethanamide, 4-{[2-(1h-imidazol-5-yl)ethyl]carbamoyl}butanoic acid, 3cm03muj69
    Molecular Formula
    C10H15N3O3
    Molecular Weight
    225.24  g/mol
    InChI Key
    KZIMLUFVKJLCCH-UHFFFAOYSA-N
    FDA UNII
    3CM03MUJ69
    Imidazolyl Ethanamide Pentandioic Acid is an orally bioavailable small molecule, with potential hematopoiesis inducing and antiviral activities. Upon oral administration, myelo001 stimulates the differentiation of bone marrow cells of the leukocytic, lymphocytic, and erythrocytic lineages, and prevents apoptosis of hematopoietic cells. This prevents chemotherapy-induced neutropenia (CIN), inhibits the risk of infections, increases tolerance and allows for the continuation of the neutropenia-inducing chemotherapeutic agent. In addition, myelo 001 has antiviral properties.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    5-[2-(1H-imidazol-5-yl)ethylamino]-5-oxopentanoic acid
    2.1.2 InChI
    InChI=1S/C10H15N3O3/c14-9(2-1-3-10(15)16)12-5-4-8-6-11-7-13-8/h6-7H,1-5H2,(H,11,13)(H,12,14)(H,15,16)
    2.1.3 InChI Key
    KZIMLUFVKJLCCH-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=C(NC=N1)CCNC(=O)CCCC(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    3CM03MUJ69
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 5-(2-(1h-imidazol-4-yl)ethylamino)-5-oxopentanoic Acid

    2. Dicarbamin

    3. Imidazolyl Ethanamide Pentandioic Acid

    4. Pentanedioic Acid Imidazolyl Ethanamide

    5. Vitaglutam

    2.3.2 Depositor-Supplied Synonyms

    1. 219694-63-0

    2. Ingamine

    3. Imidazolyl Ethanamide Pentandioic Acid

    4. Pentanedioic Acid Imidazolyl Ethanamide

    5. 4-{[2-(1h-imidazol-5-yl)ethyl]carbamoyl}butanoic Acid

    6. 3cm03muj69

    7. Pentanoic Acid, 5-[[2-(1h-imidazol-4-yl)ethyl]amino]-5-oxo-

    8. 4-[2-(1h-imidazol-4-yl)-ethylcarbamoyl]-butyric Acid

    9. Dicarbamin

    10. Vitaglutam

    11. Pentanoic Acid, 5-((2-(1h-imidazol-4-yl)ethyl)amino)-5-oxo-

    12. Agn-pc-0mw29y

    13. 4-([2-(1h-imidazol-5-yl)ethyl]carbamoyl)butanoic Acid

    14. 5-[2-(1h-imidazol-5-yl)ethylamino]-5-oxopentanoic Acid

    15. Unii-3cm03muj69

    16. Schembl8282926

    17. Chembl4297291

    18. Schembl18381264

    19. 5-(2-(1h-imidazol-4-yl)ethylamino)-5-oxopentanoic Acid

    20. Dtxsid90433141

    21. Zinc40493529

    22. Akos002807987

    23. Db11944

    24. D11250

    25. F75163

    26. Imidazolyl Ethanamide Pentandioic Acid [who-dd]

    27. Q27257036

    28. 4-{[2-(1h-imidazol-5-yl)ethyl]carbamoyl}butanoicacid

    29. 6-(2-(1h-imidazol-4-yl)ethylamino)-5-oxohexanoic Acid

    30. 5-((2-(1h-imidazol-5-yl)ethyl)amino)-5-oxopentanoic Acid

    2.4 Create Date
    2006-10-25
    3 Chemical and Physical Properties
    Molecular Weight 225.24 g/mol
    Molecular Formula C10H15N3O3
    XLogP3-0.7
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count7
    Exact Mass225.11134135 g/mol
    Monoisotopic Mass225.11134135 g/mol
    Topological Polar Surface Area95.1 Ų
    Heavy Atom Count16
    Formal Charge0
    Complexity246
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antiviral Agents

    Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)

    4.2 ATC Code

    J - Antiinfectives for systemic use

    J05 - Antivirals for systemic use

    J05A - Direct acting antivirals

    J05AX - Other antivirals

    J05AX21 - Pentanedioic acid imidazolyl ethanamide