Please Wait
Applying Filters...
menu
    • menu
    PharmaCompass Sponsored Ads

    Virtual Booth

    Contact Supplier

    Jai Radhe Sales is your partner for all your sourcing needs.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.

    Virtual Booth

    Contact Supplier

    Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Menu

    Isopropyl Palmitate

    ACTIVE PHARMA INGREDIENTS

    RELATED EXCIPIENT COMPANIES

    MARKET PLACE

    REF. STANDARDS & IMPURITIES

    PharmaCompass
    $ API Ref.Price (USD/KG) : 3Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 142-91-6, Isopropyl hexadecanoate, Hexadecanoic acid, 1-methylethyl ester, Isopalm, Deltyl prime, Wickenol 111
    Molecular Formula
    C19H38O2
    Molecular Weight
    298.5  g/mol
    InChI Key
    XUGNVMKQXJXZCD-UHFFFAOYSA-N
    FDA UNII
    8CRQ2TH63M
    isopropyl palmitate is a natural product found in Bellis perennis and Glehnia littoralis with data available.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    propan-2-yl hexadecanoate
    2.1.2 InChI
    InChI=1S/C19H38O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(20)21-18(2)3/h18H,4-17H2,1-3H3
    2.1.3 InChI Key
    XUGNVMKQXJXZCD-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCCCCCCCCCCCCCCC(=O)OC(C)C
    2.2 Other Identifiers
    2.2.1 UNII
    8CRQ2TH63M
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 142-91-6

    2. Isopropyl Hexadecanoate

    3. Hexadecanoic Acid, 1-methylethyl Ester

    4. Isopalm

    5. Deltyl Prime

    6. Wickenol 111

    7. Deltyl

    8. Emerest 2316

    9. Isopal

    10. Propal

    11. Tegester Isopalm

    12. Ja-fa Ippkessco

    13. Sinnoester Pit

    14. Crodamol Ipp

    15. Plymouth Ipp

    16. Starfol Ipp

    17. Unimate Ipp

    18. Kessco Ipp

    19. Emcol-ip

    20. Isopropyl N-hexadecanoate

    21. Stepan D-70

    22. Palmitic Acid, Isopropyl Ester

    23. Nikkol Ipp

    24. Estol 103

    25. Usaf Ke-5

    26. 1-methylethyl Hexadecanoate

    27. Ja-fa Ipp

    28. Kessco Isopropyl Palmitate

    29. Propan-2-yl Hexadecanoate

    30. Hexadecanoic Acid, Isopropyl Ester

    31. Hariol Ipp

    32. Tegosoft P

    33. Liponate Ipp

    34. Lexol Ipp

    35. Nsc 69169

    36. Palmitic Acid Isopropyl Ester

    37. 2-propyl Hexadecanoate

    38. Estol 1517

    39. Isopropyl Palmitate (nf)

    40. Isopropyl Palmitate [nf]

    41. Nsc-69169

    42. 8crq2th63m

    43. Chebi:84262

    44. Isopropyl Ester Of Hexadecanoic Acid

    45. Ncgc00164128-01

    46. We(2:0(1me)/16:0)

    47. Dsstox_cid_7104

    48. Dsstox_rid_78312

    49. Dsstox_gsid_27104

    50. Cas-142-91-6

    51. Hsdb 2647

    52. Einecs 205-571-1

    53. Mfcd00008993

    54. Unii-8crq2th63m

    55. Brn 1786567

    56. Ai3-05733

    57. Iso-propylpalmitate

    58. Isopropyl-palmitate

    59. Palmitic Acid Esters

    60. Palmitic Acid Isopropyl

    61. Radia 7200

    62. Ec 205-571-1

    63. 1-methylethyl Hexandecanoate

    64. Schembl7743

    65. Palmitic Acid-isopropyl Ester

    66. 4-02-00-01167 (beilstein Handbook Reference)

    67. Isopropyl Palmitate, >=90%

    68. Chembl139055

    69. Ipp 90

    70. Dtxsid9027104

    71. Isopropyl Palmitate [ii]

    72. Hexadecanoic Acid Isopropyl Ester

    73. Isopropyl Palmitate [hsdb]

    74. Isopropyl Palmitate [inci]

    75. Wln: 15voy1 & 1

    76. Isopropyl Palmitate [vandf]

    77. Isopropyl Palmitate [mart.]

    78. Nsc69169

    79. Zinc8214589

    80. Tox21_112085

    81. Tox21_202558

    82. Isopropyl Palmitate [usp-rs]

    83. Isopropyl Palmitate [who-dd]

    84. Lmfa07010675

    85. Akos015902011

    86. Tox21_112085_1

    87. Isopropyl Palmitate [ep Impurity]

    88. Ncgc00164128-02

    89. Ncgc00260107-01

    90. Bs-15396

    91. Hexadecanoic Acidisopropyl N-hexadecanoate

    92. Isopropyl Palmitate [ep Monograph]

    93. Isopropyl Palmitate, Technical Grade, 90%

    94. Db-042654

    95. Ft-0631830

    96. P0005

    97. 1-methylethyl Ester1-methylethyl Hexandecanoate

    98. D04632

    99. A885074

    100. Sr-01000944752

    101. J-007718

    102. Q2631777

    103. Sr-01000944752-1

    104. Isopropyl Hexadecanoate, European Pharmacopoeia (ep) Reference Standard

    105. Isopropyl Palmitate, United States Pharmacopeia (usp) Reference Standard

    106. Isopropyl Palmitate, Pharmaceutical Secondary Standard; Certified Reference Material

    2.4 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 298.5 g/mol
    Molecular Formula C19H38O2
    XLogP38.2
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count16
    Exact Mass298.287180451 g/mol
    Monoisotopic Mass298.287180451 g/mol
    Topological Polar Surface Area26.3 Ų
    Heavy Atom Count21
    Formal Charge0
    Complexity224
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Therapeutic Uses

    Several pharmacopoeias recommend the membrane filtration method for the sterility test of ophthalmic ointments. Isopropyl myristate, a fatty acid ester that exhibits high toxicity mainly against Gram-negative microorganisms, is indicated as a solvent for ointments.

    PMID:16831530 Cardoso VM et al; J Pharm Biomed Anal 42 (5): 630-4 (2006)

    ... Due to their distinct advantages such as enhanced drug solubility, thermodynamic stability, facile preparation, and low cost, uses and applications of microemulsions have been numerous. Recently, there is a surge in the exploration of microemulsion for transdermal drug delivery for their ability to incorporate both hydrophilic (5-fluorouracil, apomorphine hydrochloride, diphenhydramine hydrochloride, tetracaine hydrochloride, and methotrexate) and lipophilic drugs (estradiol, finasteride, ketoprofen, meloxicam, felodipine, and triptolide) and enhance their permeation.... Besides surfactants, oils can also act as penetration enhancers (oleic acid, linoleic acid, isopropyl myristate, isopropyl palmitate, etc.). ...

    PMID:19016057 Azeem A et al; Drug Dev Ind Pharm 35 (5): 525-47 (2009)

    4.2 Drug Warning

    Cosmetics continue to be used by acne-prone individuals. ... The data presented were gleaned from the rabbit ear assay, which is not an ideal animal model but is the best we have. If an ingredient is negative in the rabbit ear assay, we feel it is safe on the acne-prone skin. A strong, positive ingredient or cosmetic should be avoided. Ingredient offenders include isopropyl myristate and its analogs, such as isopropyl palmitate, isopropyl isostearate, butyl stearate, isostearyl neopentanoate, myristyl myristate, decyl oleate, octyl stearate, octyl palmitate or isocetyl stearate, and new introductions by the cosmetic industry, such as propylene glycol-2 (PPG-2) myristyl propionate...

    PMID:6229554 Fulton JE Jr et al; J Am Acad Dermatol 10 (1): 96-105 (1984)

    5 Pharmacology and Biochemistry
    5.1 Absorption, Distribution and Excretion

    Palmitic acid is a component of most animal fats, comprising up to 50% of them. The acid is normally metabolized by beta-oxidation or stored in fat deposits, as are most of the alcohol moieties after they are oxidized to fatty acids. The terminal groups of the iso-alcohols may yield acetone for excretion or for further metabolism. /Palmitic acid/

    Christian M, ed; J American College of Toxicology 1 (2): 13-35 (1982)