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    Isothipendyl Hydrochloride

    INTERMEDIATES

    MARKET PLACE

    PharmaCompass
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    2D Structure
    Also known as: 1225-60-1, Andantol, Theruhistin, Adantol, Isothipendyl hcl, Isothipendyl monohydrochloride
    Molecular Formula
    C16H20ClN3S
    Molecular Weight
    321.9  g/mol
    InChI Key
    RQHCFTORMXCNGP-UHFFFAOYSA-N
    FDA UNII
    953AP1LBV8
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine;hydrochloride
    2.1.2 InChI
    InChI=1S/C16H19N3S.ClH/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-16(15)19;/h4-10,12H,11H2,1-3H3;1H
    2.1.3 InChI Key
    RQHCFTORMXCNGP-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(CN1C2=CC=CC=C2SC3=C1N=CC=C3)N(C)C.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    953AP1LBV8
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 10-(2-dimethylamino-2-methylethyl)-10h-pyrido(3,2- B)(1,4)benzothiazine

    2. Andantol

    3. Andanton

    4. Estamyl

    5. Isothipendyl

    6. Sedermyl

    2.3.2 Depositor-Supplied Synonyms

    1. 1225-60-1

    2. Andantol

    3. Theruhistin

    4. Adantol

    5. Isothipendyl Hcl

    6. Isothipendyl Monohydrochloride

    7. Isothipendyl Hydrochloride [jan]

    8. Andanton

    9. Nilergex

    10. Nsc 169186

    11. Nsc-169186

    12. Isothipendyl (hydrochloride)

    13. 10-(2-dimethylaminopropyl)-10h-pyrido(3,2-b)(1,4)benzothiazine Hydrochloride

    14. 953ap1lbv8

    15. N-dimethylaminoisopropylthiophenylpyridylamine Hydrochloride

    16. 34433-15-3

    17. Nsc169186

    18. (+/-)-isothipendyl Hydrochloride

    19. 10h-pyrido(3,2-b)(1,4)benzothiazine-10-ethanamine, N,n,2-trimethyl-, Monohydrochloride

    20. N,n-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine;hydrochloride

    21. Adanton Hydrochloride

    22. Udantol Hydrochloride

    23. Nilergex Hydrochloride

    24. Isothipendyl Hydrochloride (jan)

    25. Theruhistin Hydrochloride

    26. Einecs 214-957-9

    27. Unii-953ap1lbv8

    28. Andantol (tn)

    29. Einecs 252-022-7

    30. 10-(2-dimethylaminopropyl)-1-azaphenothiazine Hydrochloride

    31. Dimethylamino-isopropyl-thiophenyl-pyridylamin Hydrochlorid [german]

    32. Ncgc00181101-01

    33. 10-(2-dimethylaminopropyl)-(1)-4-azaphenthiazin Hydrochlorid [german]

    34. 10-(2-dimethylaminopropyl)-9-thia-1,10-diazaanthracene Hydrochloride

    35. 10-(2-dimethylamino-2-methylethyl)-10h-pyrido(3,2-b)(1,4)benzothiazine Hydrochloride

    36. 10h-pyrido(3,2-b)(1,4)benzothiazine, 10-(2-(dimethylamino)propyl)-, Monohydrochloride

    37. Dsstox_cid_26845

    38. Dsstox_rid_81955

    39. Dsstox_gsid_46845

    40. Schembl230214

    41. Chembl2107246

    42. Dtxsid1046845

    43. Chebi:31734

    44. Dimethylamino-isopropyl-thiophenyl-pyridylamin Hydrochlorid

    45. 10-(2-dimethylaminopropyl)-(1)-4-azaphenthiazin Hydrochlorid

    46. Tox21_112717

    47. Isothipendyl Hydrochloride [mi]

    48. 10-(2-(dimethylamino)propyl)-10h-pyrido(3,2-b)(1,4)benzothiazine Hydrochloride

    49. 10h-pyrido(3,2-b)(1,4)benzothiazine, 10-(2-dimethylamino-2-methylethyl)-, Hydrochloride

    50. Isothipendyl Hydrochloride [mart.]

    51. Cas-1225-60-1

    52. Isothipendyl Hydrochloride [who-dd]

    53. Ft-0700699

    54. Isothipendyl Hydrochloride, (+/-)-

    55. D01143

    56. Q27271733

    57. 10h-pyrido[3,4]benzothiazine, 10-(2-dimethylamino-2-methylethyl)-, Hydrochloride

    58. 10h-pyrido[3,4]benzothiazine, 10-[2-(dimethylamino)propyl]-, Monohydrochloride

    59. 10h-pyrido[3,4]benzothiazine-10-ethanamine, N,n,2-trimethyl-, Monohydrochloride

    60. N,n,alpha-trimethyl-10h-pyrido[3,2-b][1,4]benzothiazine-10-ethanamine Hydrochloride

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 321.9 g/mol
    Molecular Formula C16H20ClN3S
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count3
    Exact Mass321.1066465 g/mol
    Monoisotopic Mass321.1066465 g/mol
    Topological Polar Surface Area44.7 Ų
    Heavy Atom Count21
    Formal Charge0
    Complexity323
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Histamine Antagonists

    Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only. (See all compounds classified as Histamine Antagonists.)