1. Kaolinite
1. 1332-58-7
2. China Clay
3. Argilla
4. Porcelain Clay
5. Bolus Alba
6. White Bole
7. Kaolin(superfine)
8. Glomax
9. Light Kaolin
10. Hydrated Aluminum Silicate
11. Kaolin Clay Slurry
12. Bentone
13. Alphagloss
14. Altowhites
15. Alfaplate
16. Alphacoat
17. Altowhite
18. Apsilex
19. Argiflex
20. Comalco
21. Electros
22. Emathlite
23. Hydrite
24. Kaopaous
25. Langford
26. Mcnamee
27. Parclay
28. Vanclay
29. Fitrol
30. Arcilla Blanca
31. Oxo-oxoalumanyloxy-[oxo(oxoalumanyloxy)silyl]oxysilane;dihydrate
32. Argilla Alba
33. Comalco Kaolin
34. Osmo Kaolin
35. Kaolin Colloidal
36. Beta Coat
37. Astra-glaze
38. Snow Tex
39. Asp Ultrafine
40. Kao-gel
41. Century Hc
42. Kaophills-2
43. Aa Kaolin
44. Clay (kaolin)
45. Acidic White Clays
46. Bol Blanc
47. Asp (mineral)
48. Burgess 10
49. Airflo V 8
50. Amazon 88
51. Amazon 90
52. Argirec B 22
53. Argirec Kn 15
54. Bilt Plate 156
55. Fitrol Desiccite 25
56. Clays, White, Acidic
57. Amazon Kaolin 855d
58. Kaolin [usp:jan]
59. Cb 1 (clay)
60. Cb 2 (clay)
61. Clay 347
62. Aluminum Silicate Hydroxide
63. Unii-24h4nwx5co
64. Metakaolin
65. Kaolinum
66. Clay Nanopowder
67. Clay Slurry
68. Kaolin Nanoclay
69. Nanoclay Powder
70. Ccris 9288
71. Hsdb 630
72. Perlite Clay Mix
73. Clay Nanoparticles
74. Epa Pesticide Chemical Code 100104
75. Expanded Perlite Powder
76. Perlite Nanoclay Powder
77. Halloysite Clay Nanotubes
78. Aluminium Silicate Dihydrate
79. Aluminum Silicate (hydrated)
80. Nanoclay Montmorillonite 20a
81. Expanded Perlite Nanoparticles
82. Montmorillonite Bentonite Clay
83. Halloysite Nanotubes Properties
84. Chembl3833365
85. Chebi:140503
86. Nanoclay Modified Asphalt Materials
87. Expanded Perlite Powder / Nanopowder
88. Shelsite 30b Montmorillonite Nanoparticles
89. Ft-0627569
90. J-521617
91. 95077-05-7
| Molecular Weight | 258.16 g/mol |
|---|---|
| Molecular Formula | Al2H4O9Si2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 4 |
| Exact Mass | 257.902462 g/mol |
| Monoisotopic Mass | 257.902462 g/mol |
| Topological Polar Surface Area | 98 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 167 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 3 |
Antidiarrheals; Pharmaceutic Aids
National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)
/Kaolin/ either alone or as...mixt with pectin, is used medicinally as an adsorbent...of value chiefly in treatment of diarrhea caused by agents capable of being adsorbed, as, for example, diarrhea of food poisoning or dysentery.
Osol, A. and J.E. Hoover, et al. (eds.). Remington's Pharmaceutical Sciences. 15th ed. Easton, Pennsylvania: Mack Publishing Co., 1975., p. 751
Kaolin has...been used in treatment of chronic ulcerative colitis, but it is doubtful whether any adsorptive capacity is retained by time prepn reaches colon.
Osol, A. and J.E. Hoover, et al. (eds.). Remington's Pharmaceutical Sciences. 15th ed. Easton, Pennsylvania: Mack Publishing Co., 1975., p. 751
VET: adsorbent, protective antidiarrheal. A physical adsorbent with hydrophilic capacity. Topical skin & GI protectant. It incr bulk & slows .. Passage of feces. Has/ ability to absorb toxins...topically & intrauterine in addn to GI.
Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 297
For more Therapeutic Uses (Complete) data for KAOLIN (8 total), please visit the HSDB record page.
... Formulation changes ... have occurred with Kaopectate ... The current Kaopectate marketed is not the formulation ... with Kaolin and Pectin. In the late 1980's or early '90s, the manufacturer reformulated the product to contain attapulgite. Then in 2003, the sponsor reformulated the product again, this time to include bismuth subsalicylate as the active ingredient. ...
FDA Safety Drug Page. Drug Topics April 19, 2004. Available from the website www.fda.gov/cder/drug/mederrors/kaopectate.pdf as of July 25, 2007
If/...kaolin-containing product must be used...should be given...2 hr before lincomycin. If this...proves impractical, lincomycin may be administered by injection or a nondiarrhea-producing antibiotic should be substituted.
Evaluations of Drug Interactions. 2nd ed. and supplements. Washington, DC: American Pharmaceutical Assn., 1976, 1978., p. 136
Inert except for dangers of obstruction, perforation, & granuloma formation.
Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-95
The use of antidiarrheal mixtures containing opioids or poorly absorbed antibacterial agents with adsorbents and protectants (most commonly, kaolin and pectin) and antispasmodic agents is unwarranted, since additional benefits beyond those afforded by the single effective agent are questionable and the patient is subjected to the added expense and the combined adverse effects of the individual ingredients.
American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 935
Practically non-toxic: probable oral lethal dose (human) above 15 g/kg; more than 1 quart (2.2 lb) for 70 kg person (150 lb).
Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-95
Antidiarrheals
Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition. (See all compounds classified as Antidiarrheals.)
A - Alimentary tract and metabolism
A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents
A07B - Intestinal adsorbents
A07BC - Other intestinal adsorbents
A07BC02 - Kaolin
Kaolin and pectin are not absorbed following oral administration.
McEvoy, G.K. (ed.). American Hospital Formulary Service--Drug Information 94. Bethesda, MD: American Society of Hospital Pharmacists, Inc. 1994 (Plus Supplements)., p. 1879
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