1. Acular
2. Toradol
1. 74103-07-4
2. Ketorolac Tris Salt
3. Toradol
4. Acular
5. Ketorolac (tromethamine Salt)
6. Ketorolac Tromethamine Salt
7. Ketorolac Trometamol
8. Acular Ls
9. Acuvail
10. Lixidol
11. Acular Pf
12. Sprix
13. Dolac
14. Tarasyn
15. Ketorolac (toradol)
16. 2-amino-2-(hydroxymethyl)propane-1,3-diol 5-benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylate
17. Nsc-758637
18. 4eve5946bq
19. Syntex
20. Toradol (tn)
21. (+/-)-5-benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic Acid Tris Salt
22. 2-amino-2-(hydroxymethyl)propane-1,3-diol;5-benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic Acid
23. Godek
24. Acular Preservative Free
25. Ketorolac Tromethamine;ketorolac Tris Salt;rs37619 Tromethamine Salt
26. Chebi:6130
27. Smr000058461
28. Ketorolac Tromethamine [usan]
29. Tromethamine Ketorolac
30. Sr-01000075948
31. Rs-37619
32. Unii-4eve5946bq
33. Toratex
34. Droal
35. Ketorolactrissalt
36. Tora-dol
37. Ketorolac Tromethamine [usan:usp]
38. Acular (tn)
39. Mfcd00887595
40. Bppc
41. Spectrum_001578
42. Cpd000058461
43. Ketorolac Tromethamine Ophthalmic Solution
44. Prestwick0_000929
45. Prestwick1_000929
46. Prestwick2_000929
47. Prestwick3_000929
48. Spectrum2_001598
49. Spectrum3_001975
50. Spectrum4_000215
51. Spectrum5_001273
52. Ketrolac.tromethamine Salt
53. Schembl5036
54. Lopac0_000676
55. Bspbio_000838
56. Bspbio_003575
57. Kbiogr_000849
58. Kbioss_002058
59. (+-)-5-benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic Acid, Compound With 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
60. 2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic Acid
61. Ketorolac Tromethamine (usp)
62. Mls000069689
63. Mls001401455
64. Mls002222310
65. Divk1c_000836
66. Spectrum1503925
67. Spbio_001596
68. Spbio_003017
69. Bpbio1_000922
70. Chembl1201124
71. Dtxsid0045597
72. Hms502j18
73. Kbio1_000836
74. Kbio2_002058
75. Kbio2_004626
76. Kbio2_007194
77. Kbio3_002953
78. Rox-828
79. Rox-888
80. Ninds_000836
81. Hms1570j20
82. Hms1922k22
83. Hms2051p06
84. Hms2093m05
85. Hms2097j20
86. Hms2235n13
87. Hms3262g13
88. Hms3373m06
89. Hms3393p06
90. Hms3655e15
91. Hms3714j20
92. Ketorolac Trometamol [jan]
93. Pharmakon1600-01503925
94. Bcp02917
95. Hy-b0138
96. (+/-)-ketorolac Tromethamine Salt
97. Tox21_500676
98. Ccg-39376
99. Ketorolac Trometamol [mart.]
100. Nsc758637
101. S5698
102. Ketorolac Tromethamine [vandf]
103. Akos024386301
104. Bcp9000811
105. Ccg-101006
106. Cs-1933
107. Ketorolac Tromethamine [usp-rs]
108. Ketorolac Tromethamine [who-dd]
109. Lp00676
110. Nc00256
111. Nsc 758637
112. Idi1_000836
113. Ncgc00016159-02
114. Ncgc00016159-03
115. Ncgc00016159-04
116. Ncgc00094036-01
117. Ncgc00094036-02
118. Ncgc00094036-03
119. Ncgc00261361-01
120. 1h-pyrrolizine-1-carboxylic Acid, 5-benzoyl-2,3-dihydro, (+-)-, Compound With 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
121. As-15193
122. Ketorolac Tris Salt;ketorolac Tromethamine
123. Bcp0726000301
124. Ketorolac Tris Salt, >=99%, Crystalline
125. Ketorolac Trometamol [ep Monograph]
126. Db-055837
127. Ketorolac Trometamol For Peak Identification
128. Ketorolac Tromethamine [orange Book]
129. Eu-0100676
130. Ft-0630829
131. K0053
132. Sw197293-4
133. Ketorolac Tromethamine [usp Monograph]
134. D00813
135. K 1136
136. M02042
137. Omidria Component Ketorolac Tromethamine
138. 103k074
139. A838011
140. Ketorolac Tromethamine Component Of Omidria
141. Sr-01000946595
142. Q-201269
143. Sr-01000075948-1
144. Sr-01000075948-6
145. Sr-01000075948-8
146. Sr-01000946595-1
147. Ketorolac (+/-)-form Tromethamine Salt [mi]
148. Q27107089
149. F0001-2390
150. Ketorolac Trometamol 1.0 Mg/ml In Methanol (as Free Acid)
151. Ketorolac Trometamol, European Pharmacopoeia (ep) Reference Standard
152. Ketorolac Tromethamine, United States Pharmacopeia (usp) Reference Standard
153. Ketorolac Trometamol For Peak Identification, European Pharmacopoeia (ep) Reference Standard
154. Ketorolac Tromethamine, Pharmaceutical Secondary Standard; Certified Reference Material
155. (+/-)-5-benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic Acid, Compound With 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
156. 1h-pyrrolizine-1-1h-pyrrolizine-1-carboxylic Acid, 5-benzoyl-2,3-dihydro, (+/-)-, Compound With 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
157. 2-amino-2-(hydroxymethyl)propane-1,3-diol (1rs)-5-benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylate
158. 5-benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylate; 2-hydroxyethyl-bis(hydroxymethyl)ammonium;ketorolac Tromethamine
1. Trometamol Ketorolac
| Molecular Weight | 376.4 g/mol |
|---|---|
| Molecular Formula | C19H24N2O6 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 6 |
| Exact Mass | 376.16343649 g/mol |
| Monoisotopic Mass | 376.16343649 g/mol |
| Topological Polar Surface Area | 146 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 430 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 2 |
| 1 of 10 | |
|---|---|
| Drug Name | Acular |
| PubMed Health | Ketorolac |
| Drug Classes | Analgesic, Central Nervous System Agent, Ophthalmologic Agent |
| Drug Label | ACULAR (ketorolac tromethamine ophthalmic solution) is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs) for ophthalmic use. Its chemical name is ()-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, comp... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | 0.5% |
| Market Status | Prescription |
| Company | Allergan |
| 2 of 10 | |
|---|---|
| Drug Name | Acular ls |
| PubMed Health | Ketorolac (Into the eye) |
| Drug Classes | Ophthalmologic Agent |
| Drug Label | ACULAR LS (ketorolac tromethamine ophthalmic solution) 0.4% is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs) for ophthalmic use. Structural and Molecular Formula: C19H24N2O6Mol Wt 376.40Chemical Name... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | 0.4% |
| Market Status | Prescription |
| Company | Allergan |
| 3 of 10 | |
|---|---|
| Drug Name | Acuvail |
| PubMed Health | Ketorolac |
| Drug Classes | Analgesic, Central Nervous System Agent, Ophthalmologic Agent |
| Drug Label | ACUVAIL (ketorolac tromethamine ophthalmic solution) 0.45% is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs) for ophthalmic use. Its chemical name is ()-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic aci... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | 0.45% |
| Market Status | Prescription |
| Company | Allergan |
| 4 of 10 | |
|---|---|
| Drug Name | Ketorolac tromethamine |
| Drug Label | Ketorolac tromethamine is a member of the pyrrolo-pyrrole group of non-steroidal anti-inflammatory drugs (NSAIDs). The chemical name for ketorolac tromethamine is (acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol, and the structural form... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Solution/drops; Tablet; Injectable |
| Route | injection; Ophthalmic; Injection; Oral |
| Strength | 0.5%; 0.4%; 30mg/ml; 60mg/2ml; 10mg; 15mg/ml |
| Market Status | Prescription |
| Company | Wockhardt; Hospira; Gland Pharma; Teva; Apotex; Sandoz; Sun Pharma Global; Fresenius Kabi Usa; Hikma Maple; Alcon Pharms; Amphastar Pharm; Sagent Pharms; Pliva; Agila Speclts; Mylan; Akorn |
| 5 of 10 | |
|---|---|
| Drug Name | Sprix |
| Drug Label | Ketorolac tromethamine is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs). The chemical name for ketorolac tromethamine is ()-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, compound with 2-amino-2-(hy... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Spray, metered |
| Route | Nasal |
| Strength | 15.75mg/spray |
| Market Status | Prescription |
| Company | Luitpold |
| 6 of 10 | |
|---|---|
| Drug Name | Acular |
| PubMed Health | Ketorolac |
| Drug Classes | Analgesic, Central Nervous System Agent, Ophthalmologic Agent |
| Drug Label | ACULAR (ketorolac tromethamine ophthalmic solution) is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs) for ophthalmic use. Its chemical name is ()-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, comp... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | 0.5% |
| Market Status | Prescription |
| Company | Allergan |
| 7 of 10 | |
|---|---|
| Drug Name | Acular ls |
| PubMed Health | Ketorolac (Into the eye) |
| Drug Classes | Ophthalmologic Agent |
| Drug Label | ACULAR LS (ketorolac tromethamine ophthalmic solution) 0.4% is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs) for ophthalmic use. Structural and Molecular Formula: C19H24N2O6Mol Wt 376.40Chemical Name... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | 0.4% |
| Market Status | Prescription |
| Company | Allergan |
| 8 of 10 | |
|---|---|
| Drug Name | Acuvail |
| PubMed Health | Ketorolac |
| Drug Classes | Analgesic, Central Nervous System Agent, Ophthalmologic Agent |
| Drug Label | ACUVAIL (ketorolac tromethamine ophthalmic solution) 0.45% is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs) for ophthalmic use. Its chemical name is ()-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic aci... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | 0.45% |
| Market Status | Prescription |
| Company | Allergan |
| 9 of 10 | |
|---|---|
| Drug Name | Ketorolac tromethamine |
| Drug Label | Ketorolac tromethamine is a member of the pyrrolo-pyrrole group of non-steroidal anti-inflammatory drugs (NSAIDs). The chemical name for ketorolac tromethamine is (acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol, and the structural form... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Solution/drops; Tablet; Injectable |
| Route | injection; Ophthalmic; Injection; Oral |
| Strength | 0.5%; 0.4%; 30mg/ml; 60mg/2ml; 10mg; 15mg/ml |
| Market Status | Prescription |
| Company | Wockhardt; Hospira; Gland Pharma; Teva; Apotex; Sandoz; Sun Pharma Global; Fresenius Kabi Usa; Hikma Maple; Alcon Pharms; Amphastar Pharm; Sagent Pharms; Pliva; Agila Speclts; Mylan; Akorn |
| 10 of 10 | |
|---|---|
| Drug Name | Sprix |
| Drug Label | Ketorolac tromethamine is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs). The chemical name for ketorolac tromethamine is ()-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, compound with 2-amino-2-(hy... |
| Active Ingredient | Ketorolac tromethamine |
| Dosage Form | Spray, metered |
| Route | Nasal |
| Strength | 15.75mg/spray |
| Market Status | Prescription |
| Company | Luitpold |
Investigated for use/treatment in pain (acute or chronic).
Cyclooxygenase Inhibitors
Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
ROX-888 is a intranasal formulation of the broadly used injectible analgesic, ketorolac. It has ability to provide effective analgesia in acute medical conditions resulting in moderate-severe pain, without the disabling side effects of opioid analgesics
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