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    Laam Hydrochloride

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    PharmaCompass
    Xls

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    2D Structure
    Also known as: Laam hydrochloride, Levomethadyl acetate hcl, 43033-72-3, L-alpha-acetylmethadol hydrochloride, Levomethadyl acetate hydrochloride [usan], Mk790
    Molecular Formula
    C23H32ClNO2
    Molecular Weight
    390.0  g/mol
    InChI Key
    UXBPQRGCVJOTNT-COBSGTNCSA-N
    FDA UNII
    B54CW5KG52
    A narcotic analgesic with a long onset and duration of action.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate;hydrochloride
    2.1.2 InChI
    InChI=1S/C23H31NO2.ClH/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21;/h7-16,18,22H,6,17H2,1-5H3;1H/t18-,22-;/m0./s1
    2.1.3 InChI Key
    UXBPQRGCVJOTNT-COBSGTNCSA-N
    2.1.4 Canonical SMILES
    CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C.Cl
    2.1.5 Isomeric SMILES
    CC[C@@H](C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    B54CW5KG52
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. (3r,6r)-3-acetoxy-6-dimethylamino-4,4-diphenylheptane

    2. 6-(dimethylamino)-4,4-diphenyl-3-heptanol Acetate

    3. Acemethadone

    4. Acetylmethadol

    5. Alphacetylmethadol

    6. Amidolacetate

    7. Dimepheptanol

    8. Laam

    9. Levo Alpha Acetylmethadol

    10. Levo-alpha-acetylmethadol

    11. Levoacetylmethadol

    12. Levomethadyl

    13. Levomethadyl Acetate

    14. Methadol

    15. Methadyl Acetate

    16. Orlaam

    2.3.2 Depositor-Supplied Synonyms

    1. Laam Hydrochloride

    2. Levomethadyl Acetate Hcl

    3. 43033-72-3

    4. L-alpha-acetylmethadol Hydrochloride

    5. Levomethadyl Acetate Hydrochloride [usan]

    6. Mk790

    7. B54cw5kg52

    8. Mk-790

    9. (-)-(3s,6s)-6-(dimethylamino)-4,4-diphenyl-3-heptanol Acetate (ester), Hydrochloride

    10. (3s,6s)-6-(dimethylamino)-4,4-diphenylheptan-3-yl Acetate Hydrochloride

    11. L-acetylmethadol Hydrochloride

    12. Levomethadyl Acetate Hydrochloride (usan)

    13. Ccris 3321

    14. Levacetyl Methadol Hydrochloride

    15. Laam-hcl

    16. Alpha-l-acetylmethadol Hydrochloride

    17. Mk 790

    18. Unii-b54cw5kg52

    19. Levacetylmethadol Hydrochloride

    20. Orlaam (tn)

    21. Schembl79093

    22. Mls002320666

    23. 6-dimethylamino-4,4-diphenyl-3-heptanolacetate.hcl

    24. Chebi:6442

    25. Chembl1200817

    26. Dtxsid7020500

    27. (1s,4s)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl Acetate Hydrochloride

    28. 3-heptanol, 6-(dimethylamino)-4,4-diphenyl-, Acetate (ester), Hydrochloride, (3s,6s)-(-)-

    29. Benzeneethanol, Beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, Acetate (ester), Hydrochloride, (s-(r*,r*))-

    30. Smr001338812

    31. Laam Hydrochloride, >=98% (hplc), Solid

    32. D00840

    33. Levacetylmethadol Hydrochloride [mart.]

    34. Levomethadyl Acetate Hydrochloride [mi]

    35. Levomethadyl Acetate Hydrochloride [vandf]

    36. Levomethadyl Acetate Hydrochloride [who-dd]

    37. Q27274386

    38. Levomethadyl Acetate Hydrochloride [orange Book]

    39. 6-dimethylamino-4,4-diphenyl-3-heptanol Acetate.hcl

    40. [(3s,6s)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] Acetate;hydrochloride

    41. Benzeneethanol, .beta.-(2-(dimethylamino)propyl)-.alpha.-ethyl-.beta.-phenyl-, Acetate (ester), Hydrochloride, (s-(r*,r*))-

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 390.0 g/mol
    Molecular Formula C23H32ClNO2
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count9
    Exact Mass389.2121570 g/mol
    Monoisotopic Mass389.2121570 g/mol
    Topological Polar Surface Area29.5 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity404
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Analgesics, Opioid

    Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)