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1. 3,4 Dihydroxynorephedrine
2. 3,4-dihydroxynorephedrine
3. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol
4. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (r*,r*)-(+,-)-isomer
5. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (r*,s*)-(+-)-isomer
6. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (r*,r*), (r*,r*)-isomer
7. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (r*,s*), (r*,r*)-isomer
8. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol, (r*,r*)-isomer
9. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol, (r*,s*)-isomer
10. Alpha Methylnoradrenaline
11. Alpha Methylnorepinephrine
12. Alpha-methylnoradrenaline
13. Alpha-methylnorepinephrine
14. Cobefrine
15. Corbadrine
16. Hydrochloride, Nordefrin
17. Methylnorepinephrine
18. Neo Cobefrin
19. Neo-cobefrin
20. Neocobefrin
21. Nordefrin
22. Nordefrin Hydrochloride
23. Nordefrin Hydrochloride, (r*,r*)-(+,-)-isomer
24. Nordefrin Hydrochloride, (r*,s*)-(+,-)-isomer
25. Nordefrin Tartrate, (r*,r*), (r*,r*) Isomer
26. Nordefrin Tartrate, (r*,s*), (r*,r*) Isomer
27. Nordefrin, (r*,r*)-isomer
28. Nordefrin, (r*,s*)-isomer
29. Norephrine
1. Corbadrine
2. Neo-cobefrin
3. 829-74-3
4. Nordefrin
5. Alpha-methylnoradrenaline
6. Corbadrinum
7. Corbadrina
8. L-nordefrin
9. (-)-cobefrin
10. 4-[(1r,2s)-2-amino-1-hydroxypropyl]benzene-1,2-diol
11. L-alpha-methylnoradrenaline
12. Nordefrin, L-
13. Corbadrine [inn]
14. Ba 2818
15. Levonordefrin [usp]
16. Nordefrin (-)-form
17. Chebi:10304
18. Alpha-methylnorepinephrine
19. Nsc-757084
20. Corbadrin
21. L-.alpha.-methylnoradrenaline
22. L-norephedrine, 3,4-dihydroxy-
23. Corbadrine (inn)
24. Levonordefrin (usp)
25. R81x549e70
26. V008l6478d
27. (-)-3,4-dihydroxynorephedrine
28. Ba-2818
29. Cas-829-74-3
30. Dsstox_cid_26349
31. Dsstox_rid_81553
32. Dsstox_gsid_46349
33. Dl-corbadrine
34. 4-((1r,2s)-2-amino-1-hydroxypropyl)benzene-1,2-diol
35. L-cobefrin
36. Corbadrinum [inn-latin]
37. Corbadrina [inn-spanish]
38. (-)3,4-dihydroxynorephedrine
39. Nordefrin, (-)-
40. Sr-05000002090
41. 3,4-dihydroxynorephedrin
42. (-)-alpha-(1-aminoethyl)-3,4-dihydroxybenzyl Alcohol
43. 1,2-benzenediol, 4-(2-amino-1-hydroxypropyl)-, (r-(r*,s*))-
44. Unii-r81x549e70
45. Unii-v008l6478d
46. Alpha-me-ne
47. Ncgc00163349-01
48. Neo-cobefrin (tn)
49. Levonordefrincorbadrine
50. Spectrum_001642
51. Alpha-(1-aminoethyl)-3,4-dihydroxybenzyl Alcohol
52. Nordefrin [mi]
53. Prestwick3_000739
54. Spectrum2_001055
55. Spectrum3_000480
56. Spectrum4_000032
57. Spectrum5_000912
58. Lopac-d-5290
59. Chembl677
60. Corbadrine [mart.]
61. Nordefrin [who-dd]
62. Corbadrine [who-dd]
63. (+/-)-cobefrin
64. Bspbio_000698
65. Bspbio_002220
66. Gtpl508
67. Kbiogr_000463
68. Kbioss_002122
69. Levonordefrin [vandf]
70. 74812-63-8
71. (-)-alpha-methylnoradrenaline
72. Divk1c_000315
73. Schembl119171
74. Spectrum1500365
75. Spbio_001010
76. Levonordefrin [usp-rs]
77. Bpbio1_000768
78. Dtxsid6046349
79. Hms500p17
80. Kbio1_000315
81. Kbio2_002122
82. Kbio2_004690
83. Kbio2_007258
84. Kbio3_001440
85. Zinc34157
86. (-)-3,4-dihydroxy Norephedrine
87. Chebi:141146
88. Ninds_000315
89. Erythro-(-)-alpha-(1-aminoethyl)-3,4-dihydrobenzyl Alcohol
90. Hms1920j07
91. Hms2091p13
92. Hms2097c20
93. Hms3714c20
94. Pharmakon1600-01500365
95. Levonordefrin [orange Book]
96. Nordefrin (-)-form [mi]
97. Tox21_112051
98. Bdbm50223426
99. Benzyl Alcohol, .alpha.-(1-aminoethyl)-3,4-dihydroxy-, Erythro-(-)-
100. Ccg-40121
101. Levonordefrin [usp Monograph]
102. Mfcd00008080
103. Nsc757084
104. Akos006280500
105. Tox21_112051_1
106. Db06707
107. Nsc 757084
108. Idi1_000315
109. Ncgc00015345-01
110. Ncgc00016542-01
111. Ncgc00016542-02
112. Ncgc00016542-03
113. Ncgc00016542-04
114. Ncgc00016542-05
115. Ncgc00016542-06
116. (1r,2s)-(-)-3,4-dihydroxynorephedrine
117. Sbi-0051428.p003
118. Hy-107915
119. Ab00513909
120. Cs-0030862
121. D02388
122. Ab00052030_04
123. 829d743
124. Sr-05000002090-1
125. Sr-05000002090-2
126. Q12745763
127. 4-[(1r,2s)-2-amino-1-hydroxypropyl]-1,2-benzenediol
128. (+/-)-ga-(1-aminoethyl)-3,4-dihydroxybenzyl Alcohol
129. (-)-.alpha.-(1-aminoethyl)-3,4-dihydroxybenzyl Alcohol
130. 1,2-benzenediol, 4-((1r,2s)-2-amino-1-hydroxypropyl)-
131. Levonordefrin, United States Pharmacopeia (usp) Reference Standard
132. 1,2-benzenediol, 4-((1r,2s)-2-amino-1-hydroxypropyl)-, Rel-
133. 1,2-benzenediol, 4-(2-amino-1-hydroxypropyl)-, (r*,s*)-(+/-)-
134. 1,2-benzenediol, 4-(2-amino-1-hydroxypropyl)-, (r-(r*,s*))
135. Benzyl Alcohol, .alpha.-(1-aminoethyl)-3,4-dihydroxy-, Erythro-(+/-)-
Molecular Weight | 183.20 g/mol |
---|---|
Molecular Formula | C9H13NO3 |
XLogP3 | -0.8 |
Hydrogen Bond Donor Count | 4 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 2 |
Exact Mass | 183.08954328 g/mol |
Monoisotopic Mass | 183.08954328 g/mol |
Topological Polar Surface Area | 86.7 Ų |
Heavy Atom Count | 13 |
Formal Charge | 0 |
Complexity | 165 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 2 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Used as a topical nasal decongestant and vasoconstrictor in dentistry.
Levonordefrin is a sympathomimetic amine used as a vasoconstrictor in local anesthetic solutions. It has pharmacologic activity similar to that of Epinephrine but it is more stable than Epinephrine. In equal concentrations, Levonordefrin is less potent than Epinephrine in raising blood pressure, and as a vasoconstrictor.
Vasoconstrictor Agents
Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)
It is designed to mimic the molecular shape of adrenaline. It binds to alpha-adrenergic receptors in the nasal mucosa. Here it can, therefore, cause vasoconstriction.