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    Technical details about Levonordefrin Hydrochloride, learn more about the structure, uses, toxicity, action, side effects and more

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    Levonordefrin Hydrochloride

    APIs // Active Pharmaceutical Ingredients

    PharmaCompass

    Farmhispania Group, a leading European CDMO in HPAPI Technologies & High Potency Fermentation.

    One Pharma aims to be one of the leading generic companies in Europe.

    2D Structure
    1. Also known as: Levonordefrin hcl, 10390-18-8, Corbadrine hydrochloride, L-nordefrin hydrochloride, Nordefrin hcl, Dl-corbadrine hydrochloride
    Molecular Formula
    C9H14ClNO3
    Molecular Weight
    219.66  g/mol
    InChI Key
    YRJLEOWRVNBAOI-WFZUHFMFSA-N
    FDA UNII
    NGO8K841ZV
    A norepinephrine derivative used as a vasoconstrictor agent.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol;hydrochloride
    2.1.2 InChI
    InChI=1S/C9H13NO3.ClH/c1-5(10)9(13)6-2-3-7(11)8(12)4-6;/h2-5,9,11-13H,10H2,1H3;1H/t5-,9-;/m0./s1
    2.1.3 InChI Key
    YRJLEOWRVNBAOI-WFZUHFMFSA-N
    2.1.4 Canonical SMILES
    CC(C(C1=CC(=C(C=C1)O)O)O)N.Cl
    2.1.5 Isomeric SMILES
    C[C@@H]([C@@H](C1=CC(=C(C=C1)O)O)O)N.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    NGO8K841ZV
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 3,4 Dihydroxynorephedrine

    2. 3,4-dihydroxynorephedrine

    3. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol

    4. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (r*,r*)-(+,-)-isomer

    5. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (r*,s*)-(+-)-isomer

    6. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (r*,r*), (r*,r*)-isomer

    7. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (r*,s*), (r*,r*)-isomer

    8. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol, (r*,r*)-isomer

    9. 4-(2-amino-1-hydroxypropyl)-1,2-benzenediol, (r*,s*)-isomer

    10. Alpha Methylnoradrenaline

    11. Alpha Methylnorepinephrine

    12. Alpha-methylnoradrenaline

    13. Alpha-methylnorepinephrine

    14. Cobefrine

    15. Corbadrine

    16. Hydrochloride, Nordefrin

    17. Levonordefrin

    18. Methylnorepinephrine

    19. Neo Cobefrin

    20. Neo-cobefrin

    21. Neocobefrin

    22. Nordefrin

    23. Nordefrin Hydrochloride

    24. Nordefrin Hydrochloride, (r*,r*)-(+,-)-isomer

    25. Nordefrin Hydrochloride, (r*,s*)-(+,-)-isomer

    26. Nordefrin Tartrate, (r*,r*), (r*,r*) Isomer

    27. Nordefrin Tartrate, (r*,s*), (r*,r*) Isomer

    28. Nordefrin, (r*,r*)-isomer

    29. Nordefrin, (r*,s*)-isomer

    30. Norephrine

    2.3.2 Depositor-Supplied Synonyms

    1. Levonordefrin Hcl

    2. 10390-18-8

    3. Corbadrine Hydrochloride

    4. L-nordefrin Hydrochloride

    5. Nordefrin Hcl

    6. Dl-corbadrine Hydrochloride

    7. Ngo8k841zv

    8. U63s13uaor

    9. 61-96-1

    10. Nordefrin Hydrochloride

    11. 1,2-benzenediol,4-[(1r,2s)-2-amino-1-hydroxypropyl]-, Hydrochloride (1:1)

    12. Corbadrine Hcl

    13. (r-(r*,s*))-4-(2-amino-1-hydroxypropyl)pyrocatechol Hydrochloride

    14. [r-(r*,s*)]-4-(2-amino-1-hydroxypropyl)pyrocatechol Hydrochloride

    15. Unii-u63s13uaor

    16. (-)-nordefrin Hydrochloride

    17. Cobefrin

    18. Corbasil

    19. 4-[(1r,2s)-2-amino-1-hydroxypropyl]benzene-1,2-diol;hydrochloride

    20. Einecs 233-853-4

    21. (-)-alpha-methylnoradrenaline Hydrochloride

    22. Unii-ngo8k841zv

    23. Schembl363800

    24. Dtxsid00146134

    25. Einecs 200-524-1

    26. Nordefrin Hydrochloride [mi]

    27. (+/-)-cobefrin Hydrochloride

    28. Nordefrin Hydrochloride [who-dd]

    29. Corbadrine Hydrochloride [who-dd]

    30. Nordefrin Hydrochloride (r*,s*)-(+-)-

    31. (+/-)-.alpha.-methylnoradrenaline Hydrochloride

    32. (r*,s*)-(1)-4-(2-amino-1-hydroxypropyl)pyrocatechol Hydrochloride

    33. (+/-)-ga-(1-aminoethyl)-3,4-dihydroxybenzyl Alcohol Hydrochloride

    34. (-)-2-amino-1-(3,4-dihydroxyphenyl)propan-1-ol Hydrochloride

    35. 1,2-benzenediol, 4-((1r,2s)-2-amino-1-hydroxypropyl)-, Hydrochloride (1:1)

    36. 1,2-benzenediol, 4-((1r,2s)-2-amino-1-hydroxypropyl)-, Hydrochloride, Rel-

    37. 1,2-benzenediol, 4-((1r,2s)-2-amino-1-hydroxypropyl)-, Hydrochloride (1:1), Rel-

    38. Benzyl Alcohol, .alpha.-(1-aminoethyl)-3,4-dihydroxy-, Hydrochloride, Erythro-(+/-)-

    2.4 Create Date
    2007-12-05
    3 Chemical and Physical Properties
    Molecular Weight 219.66 g/mol
    Molecular Formula C9H14ClNO3
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count2
    Exact Mass219.0662210 g/mol
    Monoisotopic Mass219.0662210 g/mol
    Topological Polar Surface Area86.7 Ų
    Heavy Atom Count14
    Formal Charge0
    Complexity165
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Vasoconstrictor Agents

    Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)

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