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    Technical details about Lodoxamide Tromethamine, learn more about the structure, uses, toxicity, action, side effects and more

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    Lodoxamide Tromethamine

    DOSSIERs // Finished Dosage Forms

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    PharmaCompass

    Farmhispania Group, a leading European CDMO in HPAPI Technologies & High Potency Fermentation.

    One Pharma aims to be one of the leading generic companies in Europe.

    2D Structure
    1. Also known as: Schembl24175, Chembl1201175, Dtxsid20979825, Akos015894824
    Molecular Formula
    C15H17ClN4O9
    Molecular Weight
    432.77  g/mol
    InChI Key
    KUGJPYZIWCRREB-UHFFFAOYSA-N
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-amino-2-(hydroxymethyl)propane-1,3-diol;2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid
    2.1.2 InChI
    InChI=1S/C11H6ClN3O6.C4H11NO3/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21;5-4(1-6,2-7)3-8/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21);6-8H,1-3,5H2
    2.1.3 InChI Key
    KUGJPYZIWCRREB-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N.C(C(CO)(CO)N)O
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. Schembl24175

    2. Chembl1201175

    3. Dtxsid20979825

    4. Akos015894824

    2.3 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 432.77 g/mol
    Molecular Formula C15H17ClN4O9
    Hydrogen Bond Donor Count8
    Hydrogen Bond Acceptor Count11
    Rotatable Bond Count7
    Exact Mass432.0684058 g/mol
    Monoisotopic Mass432.0684058 g/mol
    Topological Polar Surface Area243 Ų
    Heavy Atom Count29
    Formal Charge0
    Complexity543
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameAlomide
    PubMed HealthLodoxamide (Into the eye)
    Drug ClassesOphthalmologic Agent
    Drug LabelALOMIDE (lodoxamide tromethamine ophthalmic solution) 0.1% is a sterile ophthalmic solution containing the mast cell stabilizer lodoxamide tromethamine for topical administration to the eyes. Lodoxamide tromethamine is a white, crystalline, water-s...
    Active IngredientLodoxamide tromethamine
    Dosage FormSolution/drops
    RouteOphthalmic
    Strengtheq 0.1% base
    Market StatusPrescription
    CompanyAlcon

    2 of 2  
    Drug NameAlomide
    PubMed HealthLodoxamide (Into the eye)
    Drug ClassesOphthalmologic Agent
    Drug LabelALOMIDE (lodoxamide tromethamine ophthalmic solution) 0.1% is a sterile ophthalmic solution containing the mast cell stabilizer lodoxamide tromethamine for topical administration to the eyes. Lodoxamide tromethamine is a white, crystalline, water-s...
    Active IngredientLodoxamide tromethamine
    Dosage FormSolution/drops
    RouteOphthalmic
    Strengtheq 0.1% base
    Market StatusPrescription
    CompanyAlcon

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