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    Technical details about Medronate Disodium, learn more about the structure, uses, toxicity, action, side effects and more

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    Medronate Disodium

    DOSSIERs // Finished Dosage Forms

    PharmaCompass

    Farmhispania Group, a leading European CDMO in HPAPI Technologies & High Potency Fermentation.

    One Pharma aims to be one of the leading generic companies in Europe.

    2D Structure
    1. Also known as: 25681-89-4, Medronate disodium [usan], Disodium methylene diphosphonate, Disodium medronate, Disodium dihydrogen methylenediphosphonate, Hay5mt18l3
    Molecular Formula
    CH4Na2O6P2
    Molecular Weight
    219.97  g/mol
    InChI Key
    RXSYPQBNTPQOTQ-UHFFFAOYSA-L
    FDA UNII
    HAY5MT18L3
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    disodium;hydroxy-[[hydroxy(oxido)phosphoryl]methyl]phosphinate
    2.1.2 InChI
    InChI=1S/CH6O6P2.2Na/c2-8(3,4)1-9(5,6)7;;/h1H2,(H2,2,3,4)(H2,5,6,7);;/q;2*+1/p-2
    2.1.3 InChI Key
    RXSYPQBNTPQOTQ-UHFFFAOYSA-L
    2.1.4 Canonical SMILES
    C(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    HAY5MT18L3
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Disodium Methanediphosphonate

    2. Methane Diphosphonate

    3. Methylene Diphosphonate

    4. Methylene Diphosphonate, (32)p-labeled

    5. Methylene Diphosphonate, Disodium Salt

    6. Methylene Diphosphonate, Tetrasodium Salt

    7. Methylene Diphosphonate, Tetrasodium Salt, (32)p-labeled

    8. Methylene Diphosphonate, Tin(4+) Salt, (113)sn-labeled

    9. Methylene Diphosphonate, Trisodium Salt

    10. Methylene Diphosphonic Acid

    2.3.2 Depositor-Supplied Synonyms

    1. 25681-89-4

    2. Medronate Disodium [usan]

    3. Disodium Methylene Diphosphonate

    4. Disodium Medronate

    5. Disodium Dihydrogen Methylenediphosphonate

    6. Hay5mt18l3

    7. Disodium Hydroxy-[[hydroxy(oxido)phosphoryl]methyl]phosphinate

    8. Methylenebisphosphonic Acid-p,p'-disodium Salt

    9. Phosphonic Acid, Methylenebis-, Disodium Dihydrogen Salt

    10. Phosphonic Acid, P , P '-methylenebis-

    11. Disodium;hydroxy-[[hydroxy(oxido)phosphoryl]methyl]phosphinate

    12. Medronate Disodium (usan)

    13. Sodium Methylenediphosphonate

    14. Unii-hay5mt18l3

    15. Disodium Methanediphosphonate

    16. Schembl133343

    17. Medronate Disodium [ii]

    18. Chembl2105165

    19. Dtxsid70948566

    20. Medronate Disodium [vandf]

    21. Medronate Disodium [mart.]

    22. Medronate Disodium [who-dd]

    23. Mfcd02258977

    24. Akos017345141

    25. D04886

    26. Q27279835

    27. Phosphonic Acid, P,p'-methylenebis-, Sodium Salt (1:2)

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 219.97 g/mol
    Molecular Formula CH4Na2O6P2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count2
    Exact Mass219.92785040 g/mol
    Monoisotopic Mass219.92785040 g/mol
    Topological Polar Surface Area121 Ų
    Heavy Atom Count11
    Formal Charge0
    Complexity147
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 1  
    Drug NameCis-mdp
    PubMed HealthTechnetium Tc 99m Medronate
    Drug ClassesDiagnostic Agent, Radiopharmaceutical Imaging
    Active IngredientTechnetium tc-99m medronate
    Dosage FormInjectable
    RouteInjection
    Strengthn/a
    Market StatusPrescription
    CompanyPharmalucence

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Bone Density Conservation Agents

    Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS. (See all compounds classified as Bone Density Conservation Agents.)

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