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Technical details about Mephentermine Sulfate, learn more about the structure, uses, toxicity, action, side effects and more

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2D Structure
1. Also known as: Mephentermine sulfate, 6190-60-9 (sulfate), Mephentermine sodium, N,2-dimethyl-1-phenylpropan-2-amine,sulfuric acid,dihydrate;n,2-dimethyl-1-phenylpropan-2-amine,sulfuric acid,dihydrate, 2-propanamine, 2,n-dimethyl-1-phenyl-, sulfate, Mls002153976
Molecular Formula
C11H19NO4S
Molecular Weight
261.34  g/mol
InChI Key
NZKLHVGUPFNBFD-UHFFFAOYSA-N

A sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maintain BLOOD PRESSURE in hypotensive states such as following SPINAL ANESTHESIA.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N,2-dimethyl-1-phenylpropan-2-amine;sulfuric acid
2.1.2 InChI
InChI=1S/C11H17N.H2O4S/c1-11(2,12-3)9-10-7-5-4-6-8-10;1-5(2,3)4/h4-8,12H,9H2,1-3H3;(H2,1,2,3,4)
2.1.3 InChI Key
NZKLHVGUPFNBFD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)(CC1=CC=CC=C1)NC.OS(=O)(=O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Mephentermine

2. Mephentermine Sulfate

3. Mephentermine Sulfate (2:1)

4. Sulfate, Mephentermine

2.2.2 Depositor-Supplied Synonyms

1. Mephentermine Sulfate

2. 6190-60-9 (sulfate)

3. Mephentermine Sodium

4. N,2-dimethyl-1-phenylpropan-2-amine,sulfuric Acid,dihydrate;n,2-dimethyl-1-phenylpropan-2-amine,sulfuric Acid,dihydrate

5. 2-propanamine, 2,n-dimethyl-1-phenyl-, Sulfate

6. Mls002153976

7. Spectrum1503250

8. Schembl6237301

9. Chembl1200996

10. Hms500l11

11. Hms1922m15

12. Hms2092p22

13. Hms2236o06

14. Hms3369h09

15. Pharmakon1600-01503250

16. Ccg-39977

17. Nsc758424

18. Ncgc00095030-01

19. Ncgc00095030-02

20. Smr001233313

21. Sr-05000001843

22. Sr-05000001843-1

2.3 Create Date
2006-03-07
3 Chemical and Physical Properties
Molecular Weight 261.34 g/mol
Molecular Formula C11H19NO4S
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass261.10347926 g/mol
Monoisotopic Mass261.10347926 g/mol
Topological Polar Surface Area95 Ų
Heavy Atom Count17
Formal Charge0
Complexity204
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adrenergic alpha-1 Receptor Agonists

Compounds that bind to and activate ADRENERGIC ALPHA-1 RECEPTORS. (See all compounds classified as Adrenergic alpha-1 Receptor Agonists.)


Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


Vasoconstrictor Agents

Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)


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