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    Methantheline Bromide

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    PharmaCompass
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    2D Structure
    Also known as: 53-46-3, Banthine, Methanthelinium bromide, Vagantin, Dixamone bromide, Frenogastrico
    Molecular Formula
    C21H26BrNO3
    Molecular Weight
    420.3  g/mol
    InChI Key
    PQMWYJDJHJQZDE-UHFFFAOYSA-M
    FDA UNII
    090519SAPF
    A quaternary ammonium compound that acts as an antimuscarinic agent. It has been used in the treatment of PEPTIC ULCER, in gastrointestinal disorders associated with smooth muscle spasm, and in the management of urinary incontinence, and may also be used for the treatment of HYPERHIDROSIS.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium;bromide
    2.1.2 InChI
    InChI=1S/C21H26NO3.BrH/c1-4-22(3,5-2)14-15-24-21(23)20-16-10-6-8-12-18(16)25-19-13-9-7-11-17(19)20;/h6-13,20H,4-5,14-15H2,1-3H3;1H/q+1;/p-1
    2.1.3 InChI Key
    PQMWYJDJHJQZDE-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    CC[N+](C)(CC)CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13.[Br-]
    2.2 Other Identifiers
    2.2.1 UNII
    090519SAPF
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Banthine

    2. Methantheline

    3. Vagantin

    2.3.2 Depositor-Supplied Synonyms

    1. 53-46-3

    2. Banthine

    3. Methanthelinium Bromide

    4. Vagantin

    5. Dixamone Bromide

    6. Frenogastrico

    7. Gastrosedan

    8. Resobantin

    9. Ulcudexter

    10. Asabaine

    11. Banthin

    12. Doladene

    13. Gastron

    14. Metantyl

    15. Metaxan

    16. Methelina

    17. Vagamin

    18. Xanteline

    19. Avagal

    20. Ulcine

    21. Mtb 51

    22. Methantheline Bromide (200 Mg)

    23. Sc 2910

    24. Banthine Bromide

    25. Methantheline (bromide)

    26. Methanthine Bromide

    27. Nsc-32145

    28. Methanthelinium Bromide [inn]

    29. 090519sapf

    30. Diethyl(2-hydroxyethyl)methylammonium Bromide Xanthene-9-carboxylate

    31. Xanthene-9-carboxylic Acid, Ester With Diethyl(2-hydroxyethyl)methylammonium Bromide

    32. Diethyl-methyl-[2-(9h-xanthene-9-carbonyloxy)ethyl]azanium;bromide

    33. Dsstox_cid_3277

    34. Ethanaminium, N,n-diethyl-n-methyl-2-((9h-xanthen-9-ylcarbonyl)oxy)-, Bromide

    35. Dsstox_rid_76953

    36. Dsstox_gsid_23277

    37. Methanthelinium Bromide (inn)

    38. Mantheline

    39. Mtb 51; Mantheline; Metantyl; Metanyl; Metaxan; Methanide

    40. Metantelinio Bromuro [dcit]

    41. Metantelinio Bromuro

    42. Gastric Mucin

    43. Methanthelinii Bromidum

    44. Bromuro De Metantelinio

    45. Cas-53-46-3

    46. Bromure De Methanthelinum

    47. Ncgc00016239-01

    48. Einecs 200-176-0

    49. Methanthelinii Bromidum [inn-latin]

    50. Nsc 32145

    51. Bromuro De Metantelinio [inn-spanish]

    52. Bromure De Methanthelinum [inn-french]

    53. Methantheline Bromide [usp]

    54. Unii-090519sapf

    55. Ulcine Bromide

    56. Banthine (tn)

    57. Beta-diethylaminoethyl Xanthene-9-carboxylate Methobromide

    58. Mls002154138

    59. Schembl250100

    60. Chebi:6818

    61. Chembl1200988

    62. Dtxsid7023277

    63. Hms1571e14

    64. Hms2098e14

    65. Hms2230k17

    66. Hms3373j03

    67. Hms3715e14

    68. Methantheline Bromide [mi]

    69. Methanthelinebromide(200mg)

    70. Nsc32145

    71. Tox21_110320

    72. Methantheline Bromide [vandf]

    73. Ammonium, Diethyl(2-hydroxyethyl)methyl-, Bromide, Xanthene-9-carboxylate

    74. Tox21_110320_1

    75. Ccg-221066

    76. Methanthelinium Bromide [mart.]

    77. Methanthelinium Bromide [who-dd]

    78. Ncgc00016239-04

    79. Ammonium, Bromide, Xanthene-9-carboxylate

    80. Smr001233445

    81. Methantheline Bromide [orange Book]

    82. D00721

    83. M-3075

    84. Sr-01000841194

    85. Sr-01000841194-2

    86. Wln: T C666 Bo Ihj Ivo2k2&2&1 &q &e

    87. Q27236434

    88. .beta.-diethylaminoethyl 9-xanthenecarboxylate Methobromide

    89. .beta.-diethylaminoethyl Xanthene-9-carboxylate Methobromide

    90. Diethyl(2-hydroxyethyl)methylammoniumbromide Xanthene-9-carboxylate

    91. Ethanaminium,n-diethyl-n-methyl-2-[(9h-xanthen-9-ylcarbonyl)oxy]-, Bromide

    92. N,n-diethyl-n-methyl-2-[(9h-xanthen-9-ylcarbonyl)oxy]ethanaminium Bromide

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 420.3 g/mol
    Molecular Formula C21H26BrNO3
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count7
    Exact Mass419.10961 g/mol
    Monoisotopic Mass419.10961 g/mol
    Topological Polar Surface Area35.5 Ų
    Heavy Atom Count26
    Formal Charge0
    Complexity426
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Muscarinic Antagonists

    Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)