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    Naphazoline Nitrate

    ACTIVE PHARMA INGREDIENTS

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    2D Structure
    Also known as: 5144-52-5, Benil, 2-(1-naphthylmethyl)-2-imidazoline nitrate, Naphcon, Sanorin, 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1h-imidazole nitrate
    Molecular Formula
    C14H15N3O3
    Molecular Weight
    273.29  g/mol
    InChI Key
    ZAHXYMFVNNUHCP-UHFFFAOYSA-N
    FDA UNII
    SC99GR1T5S
    An adrenergic vasoconstrictor agent used as a decongestant.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole;nitric acid
    2.1.2 InChI
    InChI=1S/C14H14N2.HNO3/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;2-1(3)4/h1-7H,8-10H2,(H,15,16);(H,2,3,4)
    2.1.3 InChI Key
    ZAHXYMFVNNUHCP-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.[N+](=O)(O)[O-]
    2.2 Other Identifiers
    2.2.1 UNII
    SC99GR1T5S
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Afazol Grin

    2. Ak Con

    3. Ak-con

    4. Albalon

    5. All Clear

    6. Clear Eyes

    7. Colirio Alfa

    8. Hydrochloride, Naphazoline

    9. Idril

    10. Miraclar

    11. Monohydrochloride, Naphazoline

    12. Nafazair

    13. Naphazoline Hydrochloride

    14. Naphazoline Monohydrochloride

    15. Naphcon

    16. Naphcon Forte

    17. Nitrate, Naphazoline

    18. Optazine

    19. Pensa, Vasoconstrictor

    20. Privin

    21. Privine

    22. Proculin

    23. Siozwo

    24. Tele Stulln

    25. Tele-stulln

    26. Vasoclear

    27. Vasocon

    28. Vasocon Regular

    29. Vasoconstrictor Pensa

    30. Vasonit

    2.3.2 Depositor-Supplied Synonyms

    1. 5144-52-5

    2. Benil

    3. 2-(1-naphthylmethyl)-2-imidazoline Nitrate

    4. Naphcon

    5. Sanorin

    6. 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1h-imidazole Nitrate

    7. Naphazoline Nitrate [jan]

    8. 1h-imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, Mononitrate

    9. Sc99gr1t5s

    10. Privine

    11. 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1h-imidazole; Nitric Acid

    12. 4,5-dihydro-2-(1-naphthylmethyl)-1h-imidazolium Nitrate

    13. Naphthisen

    14. Naphthizen

    15. Vistalbalon

    16. Imidazyl

    17. Naftizin

    18. Naphtyzin

    19. Proculin

    20. Rinazina

    21. Septobore

    22. Clera

    23. Minha

    24. Privin

    25. Rhinon

    26. Privine Nitrate

    27. 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1h-imidazole;nitric Acid

    28. Sanorin Spofa

    29. 10061-11-7

    30. Prizoliene A

    31. Prizoliene N

    32. Rino Naftazolina

    33. Unii-sc99gr1t5s

    34. 2-imidazoline, 2-(1-naphthylmethyl)-, Mononitrate

    35. Einecs 225-915-4

    36. Einecs 233-197-9

    37. Privine (tn)

    38. Mfcd00014316

    39. Naphazoline Nitrate (jp17)

    40. Schembl506167

    41. Chebi:7471

    42. Dtxsid60863496

    43. Amy25696

    44. Naphazoline Nitrate [mart.]

    45. Naphthylmethyl-2-imidazoline Nitrate

    46. Naphazoline Nitrate [who-dd]

    47. Akos015895243

    48. Hy-111326a

    49. Naphazoline Nitrate, >=99.0% (nt)

    50. Naphazoline Nitrate [ep Impurity]

    51. Ac-13755

    52. As-11667

    53. Naphazoline Nitrate [ep Monograph]

    54. Db-051964

    55. Cs-0109389

    56. Ft-0603669

    57. 2-(1-naphthyl-methyl)-2-imidazoline Nitrate

    58. D01021

    59. E70388

    60. Naphazoline Nitrate, Tested According To Ph.eur.

    61. A828596

    62. W-105890

    63. Q27289139

    64. 2-(1-naphthylmethyl)-4,5-dihydro-1h-imidazole Nitrate

    65. Naphazoline Nitrate, European Pharmacopoeia (ep) Reference Standard

    66. 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1h-imidazole Mononitrate

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 273.29 g/mol
    Molecular Formula C14H15N3O3
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count2
    Exact Mass273.11134135 g/mol
    Monoisotopic Mass273.11134135 g/mol
    Topological Polar Surface Area90.4 Ų
    Heavy Atom Count20
    Formal Charge0
    Complexity297
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Nasal Decongestants

    Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993) (See all compounds classified as Nasal Decongestants.)

    Adrenergic alpha-Agonists

    Drugs that selectively bind to and activate alpha adrenergic receptors. (See all compounds classified as Adrenergic alpha-Agonists.)