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    Technical details about Narphen, learn more about the structure, uses, toxicity, action, side effects and more

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    Narphen

    APIs // Active Pharmaceutical Ingredients

    PharmaCompass

    Farmhispania Group, a leading European CDMO in HPAPI Technologies & High Potency Fermentation.

    One Pharma aims to be one of the leading generic companies in Europe.

    2D Structure
    1. Also known as: 1239-04-9, Phenazocine hbr, Phenethylazocine bromide, Nih-7519, Schembl396395, Chembl2107297
    Molecular Formula
    C22H28BrNO
    Molecular Weight
    402.4  g/mol
    InChI Key
    MNMGNPZLUMHSKK-UHFFFAOYSA-N
    An opioid analgesic with actions and uses similar to MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1095)
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol;hydrobromide
    2.1.2 InChI
    InChI=1S/C22H27NO.BrH/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17;/h3-9,15-16,21,24H,10-14H2,1-2H3;1H
    2.1.3 InChI Key
    MNMGNPZLUMHSKK-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1C2CC3=C(C1(CCN2CCC4=CC=CC=C4)C)C=C(C=C3)O.Br
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Hydrobromide, Phenazocine

    2. Narphen

    3. Phenazocine

    4. Phenbenzorphan

    5. Phenethylazocine

    2.2.2 Depositor-Supplied Synonyms

    1. 1239-04-9

    2. Phenazocine Hbr

    3. Phenethylazocine Bromide

    4. Nih-7519

    5. Schembl396395

    6. Chembl2107297

    7. Dtxsid20872382

    8. 1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol;hydrobromide

    9. 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-phenethyl-2,6-methano-3-benzazocin-8-olhydrobromide

    10. 6,11-dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,6-methanobenzo[d]azocin-8-ol Hydrobromide

    2.3 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 402.4 g/mol
    Molecular Formula C22H28BrNO
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count3
    Exact Mass401.13543 g/mol
    Monoisotopic Mass401.13543 g/mol
    Topological Polar Surface Area23.5 Ų
    Heavy Atom Count25
    Formal Charge0
    Complexity432
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count3
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Narcotics

    Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. (See all compounds classified as Narcotics.)

    Analgesics, Opioid

    Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)

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