Please Wait
Applying Filters...
menu
    • menu
    Axplora- The partner of choice for complex APIs.

    Virtual Booth

    Contact Supplier

    Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients, & custom-made solutions to our customers.

    Virtual Booth

    Contact Supplier

    HTL Biotechnology is a French biotech & a global leader in the responsible development & production of pharma-grade biopolymers.

    Virtual Booth

    Contact Supplier

    EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

    Virtual Booth

    Contact Supplier

    Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

    Virtual Booth

    Contact Supplier

    Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.

    Virtual Booth

    Contact Supplier

    Menu

    Niaprazine

    FINISHED DOSAGE FORMULATIONS

    GLOBAL SALES INFORMATION

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 27367-90-4, Nopron, 1709 cerm, Niaprazine, (+)-, Niaprazine, (-)-, 1709cerm; nopron
    Molecular Formula
    C20H25FN4O
    Molecular Weight
    356.4  g/mol
    InChI Key
    RSKQGBFMNPDPLR-UHFFFAOYSA-N
    FDA UNII
    R2H3YN6E3L
    Niaprazine is a selective brain catecholamine depletor.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]pyridine-3-carboxamide
    2.1.2 InChI
    InChI=1S/C20H25FN4O/c1-16(23-20(26)17-3-2-9-22-15-17)8-10-24-11-13-25(14-12-24)19-6-4-18(21)5-7-19/h2-7,9,15-16H,8,10-14H2,1H3,(H,23,26)
    2.1.3 InChI Key
    RSKQGBFMNPDPLR-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(CCN1CCN(CC1)C2=CC=C(C=C2)F)NC(=O)C3=CN=CC=C3
    2.2 Other Identifiers
    2.2.1 UNII
    R2H3YN6E3L
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Niaprazine Trihydrochloride

    2. Nopron

    2.3.2 Depositor-Supplied Synonyms

    1. 27367-90-4

    2. Nopron

    3. 1709 Cerm

    4. Niaprazine, (+)-

    5. Niaprazine, (-)-

    6. 1709cerm; Nopron

    7. R2h3yn6e3l

    8. N-(4-(4-(4-fluorophenyl)piperazin-1-yl)butan-2-yl)nicotinamide

    9. 1709cerm

    10. 5qkw305n9f

    11. 1709-cerm

    12. Niaprazine (inn)

    13. N-(3-(4-(4-fluorophenyl)-1-piperazinyl)-1-methylpropyl)-3-pyridinecarboxamide

    14. N-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]pyridine-3-carboxamide

    15. J10.716f

    16. Niaprazine [inn]

    17. 1346q758l9

    18. Nicotinamide, N-(3-(4-(p-fluorophenyl)-1-piperazinyl)-1-methylpropyl)-

    19. 3-pyridinecarboxamide, N-(3-(4-(4-fluorophenyl)-1-piperazinyl)-1-methylpropyl)-

    20. Niaprazina

    21. Niaprazinum

    22. Niaprazine [inn:dcf]

    23. Niaprazinum [inn-latin]

    24. Niaprazina [inn-spanish]

    25. 3-pyridinecarboxamide, N-(3-(4-(4-fluorophenyl)-1-piperazinyl)-1-methylpropyl)-, (+)-

    26. 3-pyridinecarboxamide, N-(3-(4-(4-fluorophenyl)-1-piperazinyl)-1-methylpropyl)-, (-)-

    27. 119306-37-5

    28. 119328-74-4

    29. Einecs 248-431-5

    30. Unii-r2h3yn6e3l

    31. Brn 0844157

    32. N-{4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl}pyridine-3-carboxamide

    33. Nopron (tn)

    34. Niaprazine [mi]

    35. N-(3-(4-(p-fluorophenyl)-1-piperazinyl)-1-methylpropyl)nicotinamide

    36. Niaprazine [mart.]

    37. Niaprazine [who-dd]

    38. Unii-5qkw305n9f

    39. Schembl352977

    40. Chembl2105141

    41. Dtxsid10865369

    42. Chebi:135505

    43. Unii-1346q758l9

    44. Db13687

    45. Ac-36434

    46. Bs-49185

    47. Hy-105542

    48. Cs-0026220

    49. Ft-0687290

    50. D07333

    51. E75895

    52. Q631457

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 356.4 g/mol
    Molecular Formula C20H25FN4O
    XLogP32.6
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count6
    Exact Mass356.20123960 g/mol
    Monoisotopic Mass356.20123960 g/mol
    Topological Polar Surface Area48.5 Ų
    Heavy Atom Count26
    Formal Charge0
    Complexity434
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 ATC Code

    N - Nervous system

    N05 - Psycholeptics

    N05C - Hypnotics and sedatives

    N05CM - Other hypnotics and sedatives

    N05CM16 - Niaprazine