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    Oxidopamine Hydrobromide

    ACTIVE PHARMA INGREDIENTS

    PharmaCompass
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    2D Structure
    Also known as: 28094-15-7, 6-hydroxydopamine hydrochloride, 5-(2-aminoethyl)benzene-1,2,4-triol hydrochloride, 6-hydroxydopamine chloride, Oxidopamine (hydrochloride), 2,4,5-trihydroxyphenethylamine hydrochloride
    Molecular Formula
    C8H12ClNO3
    Molecular Weight
    205.64  g/mol
    InChI Key
    QLMRJHFAGVFUAC-UHFFFAOYSA-N
    FDA UNII
    9WBV30HXTL
    A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride
    2.1.2 InChI
    InChI=1S/C8H11NO3.ClH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
    2.1.3 InChI Key
    QLMRJHFAGVFUAC-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=C(C(=CC(=C1O)O)O)CCN.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    9WBV30HXTL
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 6 Hydroxydopamine

    2. 6-hydroxydopamine

    3. 6-ohda

    4. Hydrobromide, Oxidopamine

    5. Hydrochloride, Oxidopamine

    6. Oxidopamine

    7. Oxidopamine Hydrobromide

    2.3.2 Depositor-Supplied Synonyms

    1. 28094-15-7

    2. 6-hydroxydopamine Hydrochloride

    3. 5-(2-aminoethyl)benzene-1,2,4-triol Hydrochloride

    4. 6-hydroxydopamine Chloride

    5. Oxidopamine (hydrochloride)

    6. 2,4,5-trihydroxyphenethylamine Hydrochloride

    7. 6-hydroxydopamine Hcl

    8. 9wbv30hxtl

    9. 1,2,4-benzenetriol, 5-(2-aminoethyl)-, Hydrochloride

    10. 5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride

    11. 6-hydroxydopamine Hydrochloride;6-ohda Hydrochloride

    12. Nsc-233898

    13. Ncgc00094747-01

    14. Dsstox_cid_25838

    15. Dsstox_rid_81164

    16. Dsstox_gsid_45838

    17. 2-(2,4,5-trihydroxyphenyl)ethan-1-aminium Chloride

    18. Oxidopamine Hcl

    19. Cas-28094-15-7

    20. 2,5-dihydroxytyramine Hydrochloride

    21. Einecs 248-837-2

    22. Unii-9wbv30hxtl

    23. Nsc 233898

    24. 5-(2-aminoethyl)-1,2,4-benzenetriol Hydrochloride

    25. 5-(2-aminoethyl)-4-hydroxypyrocatechol Hydrochloride

    26. 6-hydroxy Dopamine Hydrochloride

    27. 4-(2-aminoethyl)-1,2,3-benzenetriol Hydrochloride

    28. 6-hydroxydopaminehydrochloride

    29. Mfcd00012895

    30. 1,2,3-benzenetriol, 4-(2-aminoethyl)-, Hydrochloride

    31. 6-ohda Hydrochloride

    32. 6-hd Hcl

    33. Mls002207273

    34. Schembl718426

    35. Spectrum1500450

    36. Chembl451197

    37. Dtxsid0045838

    38. Wln: Z2r Cq Dq Eq &gh

    39. Hms1920d14

    40. Pharmakon1600-01500450

    41. Bcp18603

    42. Hy-b1081

    43. Tox21_111324

    44. Ccg-40236

    45. Nsc233898

    46. Nsc757259

    47. Akos015894730

    48. Tox21_111324_1

    49. Cs-4648

    50. Nsc-757259

    51. Ncgc00094747-02

    52. Ncgc00167769-04

    53. 3,5-trihydroxyphenethylamine Hydrochloride

    54. As-60772

    55. Smr001306794

    56. Db-047336

    57. Ft-0638757

    58. D87854

    59. 4-(2-aminoethyl)-1,3-benzenetriol Hydrochloride

    60. A876787

    61. 6-ohda Hydrochloride6-hydroxydopamine Hydrochloride

    62. J-016968

    63. 1,3-benzenetriol, 4-(2-aminoethyl)-, Hydrochloride

    64. 1,4-benzenetriol, 5-(2-aminoethyl)-, Hydrochloride

    65. 6-hydroxydopamine Hydrochloride; 6-ohda Hydrochloride

    66. Q27273318

    67. 1,2,4-benzenetriol,5-(2-aminoethyl)-,hydrochloride(1:1)

    68. 6-hydroxydopamine Hydrochloride, >=97% (titration), Powder

    69. 1,2,4-benzenetriol,5-(2-aminoethyl)-, Hydrochloride (1:1)

    70. 1,2,4-benzenetriol, 5-(2-aminoethyl)-, Hydrochloride (1:1)

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 205.64 g/mol
    Molecular Formula C8H12ClNO3
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count2
    Exact Mass205.0505709 g/mol
    Monoisotopic Mass205.0505709 g/mol
    Topological Polar Surface Area86.7 Ų
    Heavy Atom Count13
    Formal Charge0
    Complexity142
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Sympatholytics

    Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. (See all compounds classified as Sympatholytics.)

    Adrenergic Agents

    Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (See all compounds classified as Adrenergic Agents.)