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    Technical details about Peflacin, learn more about the structure, uses, toxicity, action, side effects and more

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    Peflacin

    APIs // Active Pharmaceutical Ingredients

    PharmaCompass

    Symbiotec: Global API manufacturer, specializing in Cortico-Steroids & Steroid-Hormone APIs.

    Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

    2D Structure
    1. Also known as: 149676-40-4, Peflacine, Peflox, Pefloxacin (mesylate dihydrate), 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid, Cx28qc6fu0
    Molecular Formula
    C18H28FN3O8S
    Molecular Weight
    465.5  g/mol
    InChI Key
    LEULAXMUNMRLPW-UHFFFAOYSA-N
    FDA UNII
    CX28QC6FU0
    A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;methanesulfonic acid;dihydrate
    2.1.2 InChI
    InChI=1S/C17H20FN3O3.CH4O3S.2H2O/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21;1-5(2,3)4;;/h8-10H,3-7H2,1-2H3,(H,23,24);1H3,(H,2,3,4);2*1H2
    2.1.3 InChI Key
    LEULAXMUNMRLPW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O.CS(=O)(=O)O.O.O
    2.2 Other Identifiers
    2.2.1 UNII
    CX28QC6FU0
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2589 R.b.

    2. Abactal

    3. Dihydrate, Pefloxacin Mesylate

    4. Mesylate Dihydrate, Pefloxacin

    5. Mesylate, Pefloxacin

    6. Peflacine

    7. Pefloxacin

    8. Pefloxacin Mesylate

    9. Pefloxacin, Silver

    10. Pefloxacine

    11. R.b., 2589

    12. Silver Pefloxacin

    2.3.2 Depositor-Supplied Synonyms

    1. 149676-40-4

    2. Peflacine

    3. Peflox

    4. Pefloxacin (mesylate Dihydrate)

    5. 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic Acid

    6. Cx28qc6fu0

    7. Pefloxacin Mesilate Dihydrate

    8. Pefloxacin Mesylate Dihydrate

    9. Pefloxacinium Mesylate Dihydrate

    10. 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic Acid;methanesulfonic Acid;dihydrate

    11. 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Methanesulfonate Dihydrate

    12. Eu 5306

    13. Unii-cx28qc6fu0

    14. Peflacin

    15. Pefloxacin Mesylate Dihydrate [ep]

    16. 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Mesylate Dihydrate

    17. Mfcd01685696

    18. Rb 1589

    19. Pefloxacinmesylatedihydrate

    20. Hy-b0147b

    21. 1589mrb

    22. Hms3656n18

    23. S4119

    24. Akos015896973

    25. Ccg-269406

    26. Cs-1963

    27. Ks-1095

    28. 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Compound With Methanesulfonic Acid (1:1) Dihydrate

    29. Db-043005

    30. Ft-0631178

    31. Sw197608-4

    32. A836889

    33. Pefloxacin Mesylate Dihydrate [ep Impurity]

    34. Pefloxacin Methanesulfonate Dihydrate [mi]

    35. Pefloxacin Mesilate Dihydrate [ep Monograph]

    36. Q27275871

    37. Pefloxacin Mesilate Dihydrate, European Pharmacopoeia (ep) Reference Standard

    38. 1-ethyl-6-fluoranyl-7-(4-methylpiperazin-1-yl)-4-oxidanylidene-quinoline-3-carboxylic Acid; Methanesulfonic Acid; Dihydrate

    39. 1-ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid; Methanesulfonic Acid; Dihydrate

    2.4 Create Date
    2006-07-28
    3 Chemical and Physical Properties
    Molecular Weight 465.5 g/mol
    Molecular Formula C18H28FN3O8S
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count12
    Rotatable Bond Count3
    Exact Mass465.15811420 g/mol
    Monoisotopic Mass465.15811420 g/mol
    Topological Polar Surface Area129 Ų
    Heavy Atom Count31
    Formal Charge0
    Complexity638
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count4
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    Cytochrome P-450 CYP1A2 Inhibitors

    Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP1A2. (See all compounds classified as Cytochrome P-450 CYP1A2 Inhibitors.)

    Topoisomerase II Inhibitors

    Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)

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