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    Technical details about Pholedrine, learn more about the structure, uses, toxicity, action, side effects and more

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    Pholedrine

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    2D Structure
    Also known as: Pulsotyl, Veritol, Pressitan, 370-14-9, Paredrinol, Sympropamin
    Molecular Formula
    C10H15NO
    Molecular Weight
    165.23  g/mol
    InChI Key
    SBUQZKJEOOQSBV-UHFFFAOYSA-N
    FDA UNII
    AY28O44JGD
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[2-(methylamino)propyl]phenol
    2.1.2 InChI
    InChI=1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3
    2.1.3 InChI Key
    SBUQZKJEOOQSBV-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(CC1=CC=C(C=C1)O)NC
    2.2 Other Identifiers
    2.2.1 UNII
    AY28O44JGD
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 4-hydroxy-n-methylamphetamine

    2. 4-hydroxymethamphetamine

    3. P-hydroxymethamphetamine

    4. Pholedrin Liquidum

    5. Pholedrin-longo-isis

    6. Pholedrine Sulfate (1:1)

    7. Pholedrine Sulfate (2:1)

    8. Pholedrine, Sulfate (1:1), (+-)-isomer

    9. Pholedrine, Sulfate (2:1), (+-)-isomer

    10. Pulsotyl

    11. Veritol

    2.3.2 Depositor-Supplied Synonyms

    1. Pulsotyl

    2. Veritol

    3. Pressitan

    4. 370-14-9

    5. Paredrinol

    6. Sympropamin

    7. Foledrin

    8. Isodrinum

    9. Pholetone

    10. Stimatone

    11. Syncordan

    12. Terapinyl

    13. Varitol

    14. Veritain

    15. Epifen

    16. 4-[2-(methylamino)propyl]phenol

    17. Knoll H75

    18. 4-hydroxymethamphetamine

    19. Promethin

    20. Prometin

    21. 4-(2-(methylamino)propyl)phenol

    22. P-hydroxymethamphetamine

    23. N-methylparedrine

    24. Racemic Pholedrine

    25. 4-hydroxy-n-methylamphetamine

    26. Pholedrinum

    27. P-hydroxy-n-methylbenzedrine

    28. P-(2-methylaminopropyl)phenol

    29. (+/-)-pholedrine

    30. Isodrin (sympathomimetic)

    31. 1-(p-hydroxyphenyl)-2-methylaminopropane

    32. Oh-ma

    33. P-hydroxy-n-methylamphetamine

    34. P-hydroxy-n,alpha-dimethylphenethylamine

    35. Beta-(p-hydroxyphenyl)isopropylmethylamine

    36. Phenethylamine, P-hydroxy-n,alpha-dimethyl-

    37. Phenol, P-(2-(methylamino)propyl)-

    38. Alpha-(p-oxyphenyl)-beta-methyl Aminopropane

    39. 1-(p-oxyphenyl)-2-methylaminopropan

    40. Knoll-h75

    41. Ay28o44jgd

    42. Pholedrine (inn)

    43. Phenol, 4-(2-(methylamino)propyl)-

    44. Phenol, 4-[2-(methylamino)propyl]-

    45. P-hydroxy-n,.alpha.-dimethylphenethylamine

    46. Pholedrine [inn]

    47. .beta.-(p-hydroxyphenyl)isopropylmethylamine

    48. .alpha.-(p-hydroxyphenyl)-.beta.-methylaminopropane

    49. (+/-)-1-(4-hydroxyphenyl)-n-methyl-2-aminopropane

    50. Foledrinio

    51. Rac Pholedrine

    52. Phenol, P-[2-(methylamino)propyl]-

    53. Pholedrinum [inn-latin]

    54. Foledrinio [inn-spanish]

    55. Pholedrine [inn:ban:dcf]

    56. Einecs 206-725-0

    57. Unii-ay28o44jgd

    58. Pholedrin

    59. P-[2-(methylamino)propyl]phenol

    60. 1-(p-oxyphenyl)-2-methylaminopropan [german]

    61. Alpha-(p-hydroxyphenyl)-beta-methylaminopropane

    62. Beta(p-oxy-phenyl)isopropylmethylamin [german]

    63. Beta(p-oxy-phenyl)isopropylmethylamin

    64. Pholedrine [mi]

    65. Pholedrine [who-dd]

    66. Schembl119262

    67. Chembl2008672

    68. Dtxsid70861908

    69. P-[(2-methylamino)propyl]phenol

    70. Chebi:134798

    71. Isodrin (sympathomimetic Compound)

    72. P-[2-(methylamino)propyl]-phenol

    73. P-hydroxy-n,a-dimethylphenethylamine

    74. Akos005216720

    75. Akos017390993

    76. (+)-4-[2-(methylamino)propyl]phenol

    77. (?)-4-[2-(methylamino)propyl]phenol

    78. Nci60_042163

    79. P-hydroxymethamphetamine, (+/-)-

    80. Db-049052

    81. Alpha-(p-hydroxyphenyl-beta-methylaminopropane

    82. D08370

    83. Phenethylamine, P-hydroxy-n,.alpha.-dimethyl-

    84. P-hydroxymethamphetamine, 1.0 Mg/ml In Methanol

    85. .alpha.-(p-oxyphenyl)-.beta.-methyl Aminopropane

    86. Sr-01000944930

    87. Q7187065

    88. Sr-01000944930-1

    89. P-hydroxymethamphetamine, Analytical Standard, For Drug Analysis

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 165.23 g/mol
    Molecular Formula C10H15NO
    XLogP31.7
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count3
    Exact Mass165.115364102 g/mol
    Monoisotopic Mass165.115364102 g/mol
    Topological Polar Surface Area32.3 Ų
    Heavy Atom Count12
    Formal Charge0
    Complexity119
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Central Nervous System Stimulants

    A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)

    Sympathomimetics

    Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

    4.2 Metabolism/Metabolites

    HO-MA is a known human metabolite of p-Methoxymethamphetamine, R-(-)-.

    S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560