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    Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

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    SCI PHARMTECH Pimobendan

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    Pimobendan

    ACTIVE PHARMA INGREDIENTS

    INTERMEDIATES

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    2D Structure
    Also known as: 74150-27-9, Pimobendane, Acardi, Dl-pimobendan, Vetmedin, D-pimobendan
    Molecular Formula
    C19H18N4O2
    Molecular Weight
    334.4  g/mol
    InChI Key
    GLBJJMFZWDBELO-UHFFFAOYSA-N
    FDA UNII
    9HTU209Z0N
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one
    2.1.2 InChI
    InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)
    2.1.3 InChI Key
    GLBJJMFZWDBELO-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OC
    2.2 Other Identifiers
    2.2.1 UNII
    9HTU209Z0N
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 4,5-dihydro-6-(2-(4-methoxyphenyl)-1h-benzimidazole-5-yl)-5-methyl-3(2h)-pyridazinone

    2. Pimobendane

    3. Ud Cg 115

    4. Ud-cg 115

    5. Ud-cg115

    2.3.2 Depositor-Supplied Synonyms

    1. 74150-27-9

    2. Pimobendane

    3. Acardi

    4. Dl-pimobendan

    5. Vetmedin

    6. D-pimobendan

    7. (-)-pimobendan

    8. Pimobendan, (-)-

    9. (+)-pimobendan

    10. Pimobendanum

    11. Ud-cg 115 Bs

    12. Ud-cg 115

    13. 118428-37-8

    14. Pimobendan, (+)-

    15. Pimobendan (vetmedin)

    16. Ud-cg-115bs

    17. Racemic Pimobendan

    18. 118428-38-9

    19. Udcg-115

    20. 6-(2-(4-methoxyphenyl)-1h-benzo[d]imidazol-5-yl)-5-methyl-4,5-dihydropyridazin-3(2h)-one

    21. Ud-cg-115

    22. 3-[2-(4-methoxyphenyl)-3h-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1h-pyridazin-6-one

    23. Brn 4207330

    24. 34ap3bbp9t

    25. Chembl24646

    26. 613jxv89su

    27. 9htu209z0n

    28. Chebi:32003

    29. 3(2h)-pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1h-benzimidazol-5-yl)-5-methyl-, (+)-

    30. 3(2h)-pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1h-benzimidazol-5-yl)-5-methyl-, (-)-

    31. L-pimobendan

    32. Racemic Pinobendan

    33. 6-(2-(4-methoxyphenyl)-1h-benzo[d]imidazol-6-yl)-5-methyl-4,5-dihydropyridazin-3(2h)-one

    34. 6-[2-(4-methoxyphenyl)-1h-benzimidazol-5-yl]-5-methyl-4,5-dihydropyridazin-3(2h)-one

    35. Pimobendan [inn-spanish]

    36. Pimobendane [inn-french]

    37. Pimobendanum [inn-latin]

    38. (+)-ud-cg 115bs

    39. (-)-ud-cg 115bs

    40. Ncgc00274063-01

    41. Unii-34ap3bbp9t

    42. Unii-613jxv89su

    43. Unii-9htu209z0n

    44. Pimobendan [usan:inn:ban]

    45. Ud-cg115

    46. 3-[2-(4-methoxyphenyl)-1h-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1h-pyridazin-6-one

    47. Acardi (tn)

    48. Pimobendan - Vetmedin

    49. Pimobendan [mi]

    50. Pimobendan [inn]

    51. Pimobendan [jan]

    52. Pimobendan [usan]

    53. Pimobendan [mart.]

    54. (+)-4,5-dihydro-6-(2-(4-methoxyphenyl)-1h-benzimidazol-5-yl)-5-methyl-3(2h)-pyridazinone

    55. (-)-4,5-dihydro-6-(2-(4-methoxyphenyl)-1h-benzimidazol-5-yl)-5-methyl-3(2h)-pyridazinone

    56. 4,5-dihydro-6-[2-(4-methoxyphenyl)-1h-benzimidazol-5-yl]-5-methyl-3(2h)-pyridazinone

    57. 6-(2-(4-methoxyphenyl)-4,5-dihydro-1h-benzimidazol-5-yl)-5-methyl-3(2h)-pyridazinone

    58. Pimobendan [usp-rs]

    59. Pimobendan [who-dd]

    60. Schembl27623

    61. Mls006010188

    62. Pimobendan (jan/usan/inn)

    63. Pimobendan [green Book]

    64. Dtxsid8048280

    65. Pimobendan [ep Impurity]

    66. Pimobendan, >=98% (hplc)

    67. Hms3655i03

    68. Hms3884c21

    69. Kuc109647n

    70. Pimobendan [usp Monograph]

    71. Bcp02958

    72. Hy-b0204

    73. Ac-689

    74. Bdbm50282617

    75. Mfcd00761648

    76. S1550

    77. Akos015851937

    78. Akos015967705

    79. Ccg-267853

    80. Db11450

    81. Ks-1280

    82. 3(2h)-pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1h-benzimidazol-5-yl)-5-methyl-

    83. 6-[2-(4-methoxy-phenyl)-1h-benzoimidazol-5-yl]-5-methyl-4,5-dihydro-2h-pyridazin-3-one

    84. Ksc-210-009

    85. Pimobendan [ema Epar Veterinary]

    86. Fortekor Plus Component Pimobendan

    87. Ncgc00274063-04

    88. Ncgc00274063-05

    89. 118428-36-7

    90. Pimobendan 100 Microg/ml In Acetonitrile

    91. Smr002530068

    92. Bcp0726000255

    93. Ft-0630830

    94. P2779

    95. Pimobendan Component Of Fortekor Plus

    96. Sw219717-1

    97. D01133

    98. Ab01274800-01

    99. Ab01274800_02

    100. 150p279

    101. Q414351

    102. J-517984

    103. Pimobendan, United States Pharmacopeia (usp) Reference Standard

    104. 4,5-dihydro-6-[2-(4-methoxy-phenyl)-1h-benzimidazol-5-yl]-5-methyl-3 (2h)-pyridazinone

    105. Pimobendan For System Suitability, European Pharmacopoeia (ep) Reference Standard

    106. (+/-)-4,5-dihydro-6-(2-(p-methoxyphenyl)-5-benzimidazolyl)-5-methyl-3(2h)-pyridazinone

    107. 3(2h)-pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1h-benzimidazol-5-yl)-5-methyl-, (+/-)-

    108. 3(2h)-pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1h-benzimidazol-6-yl)-5-methyl-

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 334.4 g/mol
    Molecular Formula C19H18N4O2
    XLogP32.7
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count3
    Exact Mass334.14297583 g/mol
    Monoisotopic Mass334.14297583 g/mol
    Topological Polar Surface Area79.4 Ų
    Heavy Atom Count25
    Formal Charge0
    Complexity530
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Vasodilator Agents

    Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

    Phosphodiesterase Inhibitors

    Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases. (See all compounds classified as Phosphodiesterase Inhibitors.)

    Cardiotonic Agents

    Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)