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    Pinazepam

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    GLOBAL SALES INFORMATION

    PharmaCompass
    $ API Ref.Price (USD/KG) : 2,222Xls

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    2D Structure
    Also known as: Domar, 52463-83-9, Pinazepam [inn], Zami 905, Duna, Z-905
    Molecular Formula
    C18H13ClN2O
    Molecular Weight
    308.8  g/mol
    InChI Key
    MFZOSKPPVCIFMT-UHFFFAOYSA-N
    FDA UNII
    5286RBZ882
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    7-chloro-5-phenyl-1-prop-2-ynyl-3H-1,4-benzodiazepin-2-one
    2.1.2 InChI
    InChI=1S/C18H13ClN2O/c1-2-10-21-16-9-8-14(19)11-15(16)18(20-12-17(21)22)13-6-4-3-5-7-13/h1,3-9,11H,10,12H2
    2.1.3 InChI Key
    MFZOSKPPVCIFMT-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C#CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
    2.2 Other Identifiers
    2.2.1 UNII
    5286RBZ882
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 7-chloro-5-phenyl-1-propargyl-1,4-benzodiazepin-2- One

    2. Domar

    3. Duna

    4. Propazepam

    5. Z-905

    2.3.2 Depositor-Supplied Synonyms

    1. Domar

    2. 52463-83-9

    3. Pinazepam [inn]

    4. Zami 905

    5. Duna

    6. Z-905

    7. 7-chloro-1-propargyl-5-phenyl-2h-1,4-benzodiazepin-2-one

    8. 7-chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-2h-1,4-benzodiazepin-2-one

    9. 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-

    10. Pinazepam (inn)

    11. 7-chloro-2,3-dihydro-5-phenyl-1-propargyl-1h-1,4-benzodiazepin-2-one

    12. 2h-1,4-benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-1-(2-propynyl)-

    13. 5286rbz882

    14. Pinazepamum

    15. Pinazepamum [inn-latin]

    16. Einecs 257-934-9

    17. Brn 0758533

    18. Dea No. 2883

    19. Unii-5286rbz882

    20. Domar (tn)

    21. 7-chloro-5-phenyl-1-prop-2-ynyl-3h-1,4-benzodiazepin-2-one

    22. Pinazepam [mi]

    23. Pinazepam [mart.]

    24. Pinazepam [who-dd]

    25. Schembl155928

    26. Chembl1213352

    27. Dtxsid3023475

    28. Chebi:135315

    29. Db13335

    30. D07314

    31. Q7194856

    32. 7-chloro-5-phenyl-1-prop-2-ynyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

    33. 7-chloro-5-phenyl-1-(2-propynyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one #

    34. 7-chloro-5-phenyl-1-(prop-2-yn-1-yl)-2,3-dihydro-1h-1,4-benzodiazepin-2-one

    35. 7-chloro-5-phenyl-1-prop-2-yn-1-yl-1,3-dihydro-2h-1,4-benzodiazepin-2-one

    2.4 Create Date
    2005-03-27
    3 Chemical and Physical Properties
    Molecular Weight 308.8 g/mol
    Molecular Formula C18H13ClN2O
    XLogP33.1
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count2
    Exact Mass308.0716407 g/mol
    Monoisotopic Mass308.0716407 g/mol
    Topological Polar Surface Area32.7 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity501
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Anxiety Agents

    Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)

    4.2 ATC Code

    N - Nervous system

    N05 - Psycholeptics

    N05B - Anxiolytics

    N05BA - Benzodiazepine derivatives

    N05BA14 - Pinazepam