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2D Structure
Also known as: 2-hydroxyethyl stearate, Glycol stearate, 2-hydroxyethyl octadecanoate, 111-60-4, 9004-99-3, Polyoxyl 40 stearate
Molecular Formula
C20H40O3
Molecular Weight
328.5  g/mol
InChI Key
RFVNOJDQRGSOEL-UHFFFAOYSA-N
FDA UNII
0324G66D0E

1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-hydroxyethyl octadecanoate
2.1.2 InChI
InChI=1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3
2.1.3 InChI Key
RFVNOJDQRGSOEL-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCCCCCCCCCCCCCCCC(=O)OCCO
2.2 Other Identifiers
2.2.1 UNII
0324G66D0E
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 2-hydroxyethyl Stearate

2. Glycol Stearate

3. 2-hydroxyethyl Octadecanoate

4. 111-60-4

5. 9004-99-3

6. Polyoxyl 40 Stearate

7. Cremophor A

8. Glycol Monostearate

9. Monthybase

10. Parastarin

11. Monthyle

12. Sedetol

13. Ivorit

14. Prodhybase Ethyl

15. Prodhybas N

16. Cerasynt M

17. Clearate G

18. Cerasynt Mn

19. Cithrol Ps

20. Clindrol Seg

21. Octadecanoic Acid, 2-hydroxyethyl Ester

22. Lipo Egms

23. Cithrol 10ms

24. Polystate

25. Lactine

26. Cerasynt 660

27. Myrj

28. Tego-stearate

29. Akyporox S 100

30. Prodhybase P

31. Polystate B

32. Peg Stearate

33. Emerest 2350

34. Emerest 2640

35. Empilan 2848

36. Lamacit Ca

37. Soromin-sg

38. Emanon 3113

39. Myrj 45

40. Stearoks 6

41. Stearoxa-6

42. Nikkol Mys

43. Ethylene Glycol Stearate

44. Pegosperse S 9

45. Stearox 6

46. Emcol H 35-a

47. Arosurf 1855e40

48. Stenol 8

49. Peg-8 Stearate

50. Peg-40 Stearate

51. Prodhybase 4000

52. Stearoks 920

53. Nikkol Mys 4

54. Nonion S 2

55. Nonion S 4

56. Nissan Nonion S-2

57. Stearox 920

58. Lipal 15s

59. Nonex 28

60. Nonex 29

61. Nonex 36

62. Nonex 53

63. Nonex 54

64. Nonex 63

65. Peg-150 Stearate

66. Lipo-peg 4-s

67. Nikkol Mys 40

68. Nikkol Mys 45

69. Nikkol Mys-25

70. Nonion S 15

71. Polyoxyl 50 Stearate

72. Trydet Sa 40

73. Empilan Cp-100

74. Empilan Cq-100

75. Nissan Nonion S 15

76. Myrj 52s

77. Kessco X-211

78. Emunon 3115

79. Ethofat 60/15

80. Ethofat 60/20

81. Ethofat 60/25

82. Myrj 51

83. Myrj 53

84. Ethoxylated Stearic Acid

85. Perphinol 45/100

86. Polyoxyethylene-8-monostearate

87. Polyethylene Oxide Monostearate

88. Lipal 400-s

89. Stearic Acid, 2-hydroxyethyl Ester

90. Tegin G

91. Ionet Ms-1000

92. Emery 15393

93. Poly(oxyethylene) Stearate

94. Polyoxyethylene(8)stearate

95. Polyethylene Glycol 8 Monostearate

96. Polyethylene Glycol Stearate

97. Polyoxyl 8 Stearate

98. Polyoxyethylene 50 Stearate

99. Carbowax 1000 Monostearate

100. Carbowax 4000 Monostearate

101. Usaf Ke-11

102. Ethylene Glycol, Monostearate

103. Myrj 49

104. Myrj 52

105. Poly(oxyethylene) Stearic Acid Ester

106. Peg 100ms

107. Peg 600ms

108. Myrj 59

109. Polyethylene Glycol Monostearate #200

110. Polyethylene Glycol Monostearate #400

111. Polyethylene Glycol (100) Monostearate

112. Polyethylene Glycol Monostearate #1000

113. Polyethylene Glycol Monostearate #6000

114. Glycol, Polyethylene Monostearate #6000

115. Glycols, Polyethylene, Monostearate

116. Polyoxyethylene 40 Stearate

117. Stearic Acid, Monoester With Ethylene Glycol

118. Glycol Stearate Se

119. Poly(oxyethylene) Monostearate

120. Polyoxyethylene Stearate (mol. Wt. 600-2000)

121. Ethylene Glycol Monostearate Se

122. Polyoxyethylene 40 Monostearate

123. Glycol Monostearate Se

124. Macrogol Ester (inn)

125. S 151

126. Myrj 52 (tn)

127. Glycol, Polyethylene Monostearate #200

128. Polyoxyl 8 Stearate (usan)

129. Nsc31811

130. 0324g66d0e

131. Ncgc00188435-01

132. Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy-

133. Poly(oxy-1,2-ethanediyl), Alpha-hydro-omega-hydroxy-, Octadecanoate

134. Trydet Sa Series

135. Peg-10 Stearate

136. Slovasol Mks 16

137. Usaf Ke-9

138. Emulphor Vt-650

139. Usaf Ke-12

140. Usaf Ke-14

141. Polyoxyethylene Stearate

142. Magi 45

143. Emanon 3199

144. Stabilisant Delta-118

145. Polyethylene Oxide Stearate

146. Polyoxyethylene Monostearate

147. Pms No. 1

148. Pms No. 2

149. Polyethyleneglycols Monstearate

150. Polyethyleneglycols Monostearate

151. Lx 3

152. Mys 40

153. Mys 45

154. Peg 1000ms

155. Peg 42

156. Polyoxyethylate (9) Stearic Acid

157. Polyoxyethylene-(40)-monostearate

158. Polyoxyl 8 Stearate [usan:ban]

159. Glycol Polyethylene Monostearate #200

160. Unii-6yly96tql6

161. X-489-r

162. Macrogol Ester

163. S 541

164. Schercemol Egms

165. Alkamuls Seg

166. Ablunol Egms

167. S 1004

168. S 1012

169. S 1054

170. S 1116

171. Stearic Acid, Monoester With Polyethylene Glycol

172. Alkamuls Egms/c

173. Peg40 Stearate

174. Einecs 203-886-9

175. Pegosperse 50 Ms

176. Polyethylene Glycol Monostearate #40

177. Mfcd00051465

178. Glycols, Monostearate

179. Brn 1794033

180. Polyoxyl 40 Stearate [usan:ban:jan]

181. Peg-200 Monostearate

182. Peg-300 Monostearate

183. Peg-400 Monostearate

184. Peg-600 Monostearate

185. Polyoxyl Stearate (nf)

186. Cerasynt M (salt/mix)

187. Ethyleneglycol Monostearate

188. Polyoxyl (40) Stearate

189. Cerasynt Mn (salt/mix)

190. Peg-1000 Monostearate

191. Peg-2000 Monostearate

192. Peg-4000 Monostearate

193. Polyoxyethylene 8 Stearate

194. Dsstox_cid_6881

195. Stabilisant .delta.-118

196. 6yly96tql6

197. Dsstox_rid_78236

198. Dsstox_gsid_26881

199. Schembl10412

200. Glycol Stearate [ii]

201. Crill 20,22,23

202. Polyethylene Glycol Monosterate

203. Glycol Stearate [inci]

204. Glycol Stearate [vandf]

205. Chembl2355383

206. Dtxsid5026881

207. Unii-0324g66d0e

208. Chebi:32027

209. Chebi:167626

210. 17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl Octadecanoate

211. Polyoxyl 40 Stearate (jp15/nf)

212. Polyoxyl 40 Stearate (jp17/nf)

213. Crill 20,21,22, 23

214. Tox21_113036

215. Nsc-31811

216. Zinc56897528

217. Akos015843173

218. Octadecanoic Acid 2-hydroxyethyl Ester

219. 86418-55-5

220. Bs-48654

221. Cas-111-60-4

222. Cs-0440899

223. Ethylene Glycol Monostearate [who-dd]

224. Ft-0626337

225. N,n-bis-(1-phenyl-ethyl)-malonamide

226. S-151

227. D01542

228. F71203

229. F71256

230. L001305

231. Q5572621

232. W-109413

233. Poly(oxy-1, .alpha.-(1-oxooctadecyl)-.omega.-hydroxy-

234. Polyoxyethylene Monostearate Ester, Poe(14) Monostearate

235. Polyoxyethylene Monostearate Ester, Poe(23) Monostearate

236. Polyoxyethylene Monostearate Ester, Poe(46) Monostearate

237. Polyoxyethylene Monostearate Ester, Poe(7) Monostearate

238. Polyoxyethylene Monostearate Ester, Poe(9) Monostearate

239. Polyoxyethylene Monostearate Ester, Poe(90) Monostearate

240. Poly(oxy-1, .alpha.-hydro-.omega.-hydroxy-, Octadecanoate

241. Poly(oxy-1, 2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, Octadecanoate

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 328.5 g/mol
Molecular Formula C20H40O3
XLogP37.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count19
Exact Mass328.29774513 g/mol
Monoisotopic Mass328.29774513 g/mol
Topological Polar Surface Area46.5 Ų
Heavy Atom Count23
Formal Charge0
Complexity241
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Absorption, Distribution and Excretion

THESE ESTERS ARE HYDROLYZED IN THE BOWEL. THE FATTY ACID IS ABSORBED & METABOLIZED; AT LEAST THE SHORTER POLYOXYETHYLENE RESIDUES ARE ALSO ABSORBED, BUT THEY ARE EXCRETED UNCHANGED IN THE URINE (NO DETECTABLE METABOLISM TO OXALIC ACID IN MAN).

Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-277