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    Romifidine

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

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    2D Structure
    Also known as: 65896-16-4, N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1h-imidazol-2-amine, Romifidinum, Sedivet, 2-(2-bromo-6-fluoroanilino)-2-imidazoline, Romifidine (inn)
    Molecular Formula
    C9H9BrFN3
    Molecular Weight
    258.09  g/mol
    InChI Key
    KDPNLRQZHDJRFU-UHFFFAOYSA-N
    FDA UNII
    876351L05K
    Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species. This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved for use in humans.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine
    2.1.2 InChI
    InChI=1S/C9H9BrFN3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)
    2.1.3 InChI Key
    KDPNLRQZHDJRFU-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CN=C(N1)NC2=C(C=CC=C2Br)F
    2.2 Other Identifiers
    2.2.1 UNII
    876351L05K
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. N-(2-bromo-6-fluorophenyl)-4,5-dihydro-(1h)-imidazol-2-amine

    2. Romifidine Monohydrochloride

    3. Sedivet

    4. Sth 2130

    2.3.2 Depositor-Supplied Synonyms

    1. 65896-16-4

    2. N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1h-imidazol-2-amine

    3. Romifidinum

    4. Sedivet

    5. 2-(2-bromo-6-fluoroanilino)-2-imidazoline

    6. Romifidine (inn)

    7. Romifidine [inn]

    8. 876351l05k

    9. Romifidinum [latin]

    10. Romifidina [spanish]

    11. Romifidina

    12. Romifidine [inn:ban]

    13. Unii-876351l05k

    14. Sedivet (tn)

    15. Romifidine [mi]

    16. Romifidine [mart.]

    17. Mls006010405

    18. Schembl246009

    19. Chembl2105424

    20. Dtxsid40216103

    21. Mfcd00868606

    22. Zinc56898821

    23. Akos026348206

    24. Db11543

    25. Ncgc00532499-01

    26. Smr004701406

    27. Hy-119456

    28. Cs-0068423

    29. R0120

    30. 2-(2-bromo-6-fluorophenylamino)-2-imidazoline

    31. D08487

    32. Methyl4-chloro-3-cyclohexene-1-carboxylate

    33. Q747850

    34. Sr-01000945279

    35. Sr-01000945279-1

    36. Z1849014130

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 258.09 g/mol
    Molecular Formula C9H9BrFN3
    XLogP31.4
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count2
    Exact Mass256.99639 g/mol
    Monoisotopic Mass256.99639 g/mol
    Topological Polar Surface Area36.4 Ų
    Heavy Atom Count14
    Formal Charge0
    Complexity234
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Adrenergic alpha-2 Receptor Agonists

    Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Agonists.)

    Anesthetics

    Agents capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site. (See all compounds classified as Anesthetics.)