1. Dithionite
2. Dithionite, Sodium
3. Hyposulfite
1. Sodium Hydrosulfite
2. 7775-14-6
3. Sodium Hydrosulphite
4. Dithionous Acid, Disodium Salt
5. Sodium Sulfoxylate
6. Disodium Dithionite
7. Sodium Hypodisulfite
8. Vatrolite
9. 2k5b8f6es1
10. Chebi:66870
11. Blankit
12. Burmol
13. Hydros
14. Sodiumdithionite
15. Blankit In
16. Hydrosulfite R Conc
17. V-brite B
18. Disodium Hydrosulfite
19. Caswell No. 774
20. Ccris 1428
21. Hsdb 746
22. Sodium Hydrosulfite (na2s2o4)
23. Sodium Dithionite (na2(s2o4))
24. Einecs 231-890-0
25. Un1384
26. Epa Pesticide Chemical Code 078202
27. Unii-2k5b8f6es1
28. Sodium Dithionit
29. Sodiumhydrosulfite
30. Sodiumhydrosulphite
31. Sodium Hydro Sulfite
32. Mfcd00011640
33. Sodium Sodium Hydrosulfite
34. Dithionous Aciddisodiumsalt
35. Na2s2o4
36. Ec 231-890-0
37. Sodium Dithionite (na2s2o4)
38. Sodium Dithionite [ii]
39. Sodium Dithionite [mi]
40. Chembl3410462
41. Dtxsid9029697
42. Na2 (s2 O4)
43. Sodium Dithionite [mart.]
44. Sodium Hydrosulfite [hsdb]
45. Sodium Hydrosulfite [inci]
46. Dithionous Acid, Sodium Salt (1:2)
47. Akos015904498
48. Sodium Dithionite Or Sodium Hydrosulfite
49. Bp-13393
50. Ft-0695294
51. S0562
52. Q414560
53. Sodium Dithionite Or Sodium Hydrosulfite [un1384] [spontaneously Combustible]
| Molecular Weight | 174.11 g/mol |
|---|---|
| Molecular Formula | Na2O4S2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 0 |
| Exact Mass | 173.90333939 g/mol |
| Monoisotopic Mass | 173.90333939 g/mol |
| Topological Polar Surface Area | 119 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 60.5 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 3 |
Sodium thiosulfate is used in humans to lessen some of the side effects of cisplatin (a cancer medicine). It is also used in the emergency treatment of cyanide poisoning. Sodium thiosulfate is assumed to be intrinsically non-toxic.
OECD; SIDS Initial Assessment Reports for Sodium Dithionite (CAS No.: 7775-14-6) for SIAM 19 (October 2004). Available from, as of November 10, 2009: https://www.inchem.org/documents/sids/sids/7775146.pdf
Sulfites such as sodium pyrosulfite and sodium dithionite, applied topically to the skin of cement workers, appear to be effective in prevention of dermatitis. 9 previously proven chrome sensitive individuals were patch tested with aqueous potassium dichromate 0.5 % mixed with sodium dithionite in the proportion of 3 g/L. Not one patient developed a positive reaction to the chromate mixed with sodium dithionite, though all reacted to 0.5 % chromate in water without sodium dithionite.
European Commission, ESIS; IUCLID Dataset, Sodium dithionite (7775-14-6) (April 2006). Available from, as of November 10, 2009: https://esis.jrc.ec.europa.eu/
Probable oral lethal dose (human) 0.5-5 g/kg bw.
European Commission, ESIS; IUCLID Dataset, Sodium dithionite (7775-14-6) (April 2006). Available from, as of November 10, 2009: https://esis.jrc.ec.europa.eu/
3. 3= MODERATELY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 0.5-5 G/KG, BETWEEN 1 OZ & 1 PINT (OR 1 LB) FOR 70 KG PERSON (150 LB). /SULFITES/
Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. II-85
Sodium dithionite is not stable under physiological conditions, with the rate of decomposition increasing with increasing acidity. Upon contact with moisture, it is oxidized to hydrogen sulfite, sulfite and hydrogen sulfate, and under strongly acidic conditions it may liberate sulfur dioxide. Under anaerobic conditions (such as in the lower gastrointestinal tract), hydrogen sulfite and thiosulfate may be formed. Hydrogen sulfite can be absorbed after ingestion. It is efficiently metabolized, and the major part rapidly excreted as sulfate into the urine.
OECD; SIDS Initial Assessment Reports for Sodium Dithionite (CAS No.: 7775-14-6) for SIAM 19 (October 2004). Available from, as of October 19, 2009: https://www.inchem.org/documents/sids/sids/7775146.pdf
As sodium dithionite is chemically unstable in the presence of water and oxygen, in particular under acidic conditions, rapid conversion of sodium dithionite into various related sulfite species is expected to occur under physiological conditions. Therefore, it is justified to take account of toxicological data of sodium sulfite, sodium hydrogen sulfite, and disodium disulfite (= sodium metabisulfite) in the human health assessment of dithionite ... In this context, sodium sulfite and sodium hydrogen sulfite are considered to be the predominant chemicals that are systemically available to the body.
OECD; SIDS Initial Assessment Reports for Sodium Dithionite (CAS No.: 7775-14-6) for SIAM 19 (October 2004). Available from, as of October 19, 2009: https://www.inchem.org/documents/sids/sids/7775146.pdf
