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2D Structure
Also known as: 10163-15-2, Sodium fluorophosphate, Disodium monofluorophosphate, Disodium fluorophosphate, Sodium phosphorofluoridate, 7631-97-2
Molecular Formula
FNa2O3P
Molecular Weight
143.950  g/mol
InChI Key
BFDWBSRJQZPEEB-UHFFFAOYSA-L
FDA UNII
C810JCZ56Q

Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
disodium;fluoro-dioxido-oxo-5-phosphane
2.1.2 InChI
InChI=1S/FH2O3P.2Na/c1-5(2,3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
2.1.3 InChI Key
BFDWBSRJQZPEEB-UHFFFAOYSA-L
2.1.4 Canonical SMILES
[O-]P(=O)([O-])F.[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
C810JCZ56Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ammonium Monofluorophosphate

2. Calcium Fluorophosphate

3. Calcium Monofluorophosphate

4. Fluorophosphate

5. Fluorophosphate Hydrate, Calcium Salt

6. Fluorophosphate, Barium Salt

7. Fluorophosphate, Calcium Salt

8. Fluorophosphate, Diammonium Salt

9. Fluorophosphate, Disodium Salt

10. Fluorophosphate, Monoammonium Salt

11. Fluorophosphate, Potassium Salt

12. Fluorophosphate, Sodium Salt

13. Fluorophosphate, Tin Salt

14. Fluorophosphate, Vanadium Salt

15. Mono-tridin

16. Monofluorophosphate

17. Na-mfp

2.3.2 Depositor-Supplied Synonyms

1. 10163-15-2

2. Sodium Fluorophosphate

3. Disodium Monofluorophosphate

4. Disodium Fluorophosphate

5. Sodium Phosphorofluoridate

6. 7631-97-2

7. Phosphorofluoridic Acid, Disodium Salt

8. Disodium Phosphorofluoridate

9. Acorea

10. Sodium Fluorophosphate (na2po3f)

11. Phosphorofluoridic Acid, Sodium Salt

12. C810jcz56q

13. 12331-99-6

14. Disodium;fluoro-dioxido-oxo-lambda5-phosphane

15. Chebi:86431

16. Sodium Monofluorophosphate [usp]

17. Nsc-248

18. Phosphorofluoridic Acid, Disodium Salt (8ci,9ci)

19. Mfcd00014248

20. Extra-strength Aim

21. Sodium Monofluorophosphate (usp)

22. Sodium Monofluorophosphate (inci)

23. Sodium Monofluorophosphate [inci]

24. Ccris 9129

25. Nsc 248

26. Disodiummonofluorophosphate

27. Einecs 233-433-0

28. Colgate Anticavity Toothpaste

29. Unii-c810jcz56q

30. F-o3-p.2na

31. Ai3-16931

32. Fluorophosphoric Acid, Sodium Salt

33. Sodium Fluophosphate

34. Einecs 231-552-2

35. Phoskadent Na211

36. Sodiumphosphorofluoridate

37. Sodium Phosphorofluridate

38. Aim (tn)

39. Disodium Phosphofluoridate

40. Disodiumphosphorofluoridate

41. Disodium Fluoro-dioxido-oxo-$l^{5}-phosphane

42. Ec 233-433-0

43. Na2-p-f-o3

44. Sodium Fluorophosphate, 95%

45. Sodiumfluorophosphate(na2po3f)

46. Sodium Monofluorphosphate

47. Phosphorofluoridicacid,sodiumsalt

48. Sodium Monofluorophosphate, Usp

49. Chembl1908359

50. F-h2-o3-p

51. Dtxsid70872554

52. Hms3264b14

53. Phosphorofluoridic Acid,sodium Salt

54. Phosphorofluoridicacid, Sodium Salt

55. Amy37031

56. Fluoridophosphoric Acid Disodium Salt

57. Phosphorofluoridic Acid Disodium Salt

58. S4013

59. Akos015916166

60. Akos015960447

61. Ccg-213673

62. Db09484

63. Sodium Fluorophosphate [who-dd]

64. Superlist Name Sodium Monofluorophosphate

65. Sodium Monofluorophosphate [mart.]

66. Sy061225

67. Sodium Monofluorophosphate [usp-rs]

68. Phosphorofluoridic Acid, Disodium Salt Smfp

69. Disodium;fluoro-dioxido-oxo-$l^{5-phosphane

70. Ft-0688148

71. Phosphorofluoridic Acid, Sodium Salt (1:?)

72. D05864

73. Sodium Monofluorophosphate [orange Book]

74. A838673

75. Sodium Monofluorophosphate [usp Monograph]

76. Q3498849

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 143.950 g/mol
Molecular Formula FNa2O3P
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass143.93644758 g/mol
Monoisotopic Mass143.93644758 g/mol
Topological Polar Surface Area63.2 Ų
Heavy Atom Count7
Formal Charge0
Complexity49.8
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Indication

Sodium monofluorophosphate is indicated for the treatment of cavities


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Cariostatic Agents

Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed) (See all compounds classified as Cariostatic Agents.)


5.2 ATC Code

A - Alimentary tract and metabolism

A01 - Stomatological preparations

A01A - Stomatological preparations

A01AA - Caries prophylactic agents

A01AA02 - Sodium monofluorophosphate


A - Alimentary tract and metabolism

A12 - Mineral supplements

A12C - Other mineral supplements

A12CD - Fluoride

A12CD02 - Sodium monofluorophosphate