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    Technical details about Spaglumic Acid, learn more about the structure, uses, toxicity, action, side effects and more

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    Spaglumic Acid

    DOSSIERs // Finished Dosage Forms

    GLOBAL SALES INFORMATION

    PharmaCompass

    Symbiotec: Global API manufacturer, specializing in Cortico-Steroids & Steroid-Hormone APIs.

    Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

    2D Structure
    1. Also known as: N-acetyl-1-aspartylglutamic acid, N-acetyl-asp-glu-oh, Alpha-naag, Spectrum2_001481, Spectrum3_001845, 2-[(2-acetamido-3-carboxy-1-oxopropyl)amino]pentanedioic acid
    Molecular Formula
    C11H16N2O8
    Molecular Weight
    304.25  g/mol
    InChI Key
    OPVPGKGADVGKTG-UHFFFAOYSA-N
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-[(2-acetamido-3-carboxypropanoyl)amino]pentanedioic acid
    2.1.2 InChI
    InChI=1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)
    2.1.3 InChI Key
    OPVPGKGADVGKTG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Isospaglumic Acid

    2. N-(n-acetyl-l-alpha-aspartyl)-l-glutamic Acid

    3. N-acetyl-1-asp-glu

    4. N-acetyl-1-aspartylglutamic Acid

    5. N-acetyl-1-aspartylglutamic Acid, (l)-isomer Ion

    6. N-acetyl-1-aspartylglutamic Acid, Magnesium Salt

    7. N-acetyl-aspartyl-glutamate

    8. N-acetyl-aspartyl-glutamic Acid

    9. N-acetyl-l-alpha-aspartylglutamic Acid

    10. N-acetyl-l-aspartyl-l-glutamate

    11. N-acetylaspartylglutamate

    12. Naaga

    13. Naaga Magnesium Salt

    14. Naaga Sodium Salt

    15. Naaxia

    16. Zy 15106

    17. Zy 15109

    18. Zy-15106

    19. Zy-15109

    20. Zy15106

    21. Zy15109

    2.2.2 Depositor-Supplied Synonyms

    1. N-acetyl-1-aspartylglutamic Acid

    2. N-acetyl-asp-glu-oh

    3. Alpha-naag

    4. Spectrum2_001481

    5. Spectrum3_001845

    6. 2-[(2-acetamido-3-carboxy-1-oxopropyl)amino]pentanedioic Acid

    7. Chembl64966

    8. Schembl288515

    9. Spbio_001461

    10. Schembl21403461

    11. Chebi:95120

    12. Kbio3_002730

    13. Dtxsid10863103

    14. Hms3266k17

    15. Ccg-39200

    16. Pdsp1_000259

    17. Pdsp2_000258

    18. Ncgc00095908-01

    19. Ncgc00095908-02

    20. Db-047960

    21. Ft-0774474

    22. N-acetyl-asp-glu, >=97% (tlc), Powder

    23. L000426

    24. Q27166900

    2.3 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 304.25 g/mol
    Molecular Formula C11H16N2O8
    XLogP3-2.1
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count9
    Exact Mass304.09066547 g/mol
    Monoisotopic Mass304.09066547 g/mol
    Topological Polar Surface Area170 Ų
    Heavy Atom Count21
    Formal Charge0
    Complexity448
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count2
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Neuroprotective Agents

    Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids. (See all compounds classified as Neuroprotective Agents.)

    Histamine H1 Antagonists

    Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)

    Anti-Allergic Agents

    Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)

    Bronchodilator Agents

    Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)

    Neurotoxins

    Toxic substances from microorganisms, plants or animals that interfere with the functions of the nervous system. Most venoms contain neurotoxic substances. Myotoxins are included in this concept. (See all compounds classified as Neurotoxins.)

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