1. Actinospectacin
2. Adspec
3. Ferkel Spectam
4. Kempi
5. Prospec
6. Salmosan T
7. Salmosan-t
8. Spectam
9. Spectam, Ferkel
10. Spectinomycin Dihydrochloride, Anhydrous
11. Spectinomycin Dihydrochloride, Pentahydrate
12. Spectinomycin Hydrochloride
13. Stanilo
14. Trobicin
1. 1695-77-8
2. Actinospectacin
3. Espectinomicina
4. Trobicin
5. Antibiotic 2233wp
6. Spectam
7. Togamycin
8. Spectinomycine
9. Spectinomycinum
10. Spectinomicina [italian]
11. Actinospectacina [italian]
12. Prospec
13. Adspec
14. Spectinomycin Hydrochloride
15. Spectinomycine [inn-french]
16. Spectinomycinum [inn-latin]
17. Espectinomicina [inn-spanish]
18. M-141
19. Spectinomycin Dihydrochloride
20. 93aki1u6qf
21. Chebi:9215
22. Scm
23. Chx-3101
24. Spectinomycin (inn)
25. Actinospectacina
26. Spectinomycin [inn]
27. 22189-32-8
28. (1r,3s,5r,8r,10r,11s,12s,13r,14s)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one
29. (2r,4ar,5ar,6s,7s,8r,9s,9ar,10as)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4h-pyrano[2,3-b][1,4]benzodioxin-4-one
30. 4h-pyrano(2,3-b)(1,4)benzodioxin-4-one, Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-
31. 4h-pyrano[2,3-b][1,4]benzodioxin-4-one, Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2r,4ar,5ar,6s,7s,8r,9s,9ar,10as)-
32. M 141
33. U 18409
34. Spectinomycin [inn:ban]
35. 4h-pyrano(2,3-b)(1,4)benzodioxin-4-one, Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2r,4ar,5ar,6s,7s,8r,9s,9ar,10as)-
36. U 18409 E
37. Xk 43-1
38. U-18409e
39. Einecs 216-911-3
40. Unii-93aki1u6qf
41. Spectinomycin Hcl/ Sulphate
42. Brn 2171701
43. Specitinomycin
44. Sr-05000001868
45. (2r,4ar,5ar,6s,7s,8r,9s,9ar,10as)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-3,5a,6,7,8,9,9a,10a-octahydro-2h-benzo[[?]]pyrano[[?]][1,4]dioxin-4-one
46. Prospec (tn)
47. Adspec (tn)
48. Spcm
49. Nsc132679
50. Spectrum_000954
51. 21736-83-4
52. Prestwick0_000804
53. Prestwick1_000804
54. Prestwick2_000804
55. Prestwick3_000804
56. Spectrum2_001315
57. Spectrum3_000898
58. Spectrum4_000993
59. Spectrum5_001407
60. Spectinomycin [mi]
61. Schembl3533
62. Chembl1167
63. Bspbio_000667
64. Kbiogr_001425
65. Kbioss_001434
66. Spectinomycin [vandf]
67. Divk1c_000137
68. Spectinomycin [mart.]
69. Spbio_001409
70. Spbio_002588
71. Spectinomycin [who-dd]
72. Bpbio1_000735
73. Dtxsid9023592
74. Gtpl11127
75. Kbio1_000137
76. Kbio2_001434
77. Kbio2_004002
78. Kbio2_006570
79. Kbio3_001816
80. Ninds_000137
81. Hms2089c03
82. Spectinomycin [green Book]
83. Hy-b1828
84. Zinc53006806
85. Akos015961272
86. Ccg-208273
87. Db00919
88. Idi1_000137
89. Smp1_000276
90. Ncgc00017354-02
91. Ncgc00017354-03
92. Ncgc00017354-04
93. Ncgc00142531-01
94. Ncgc00142531-02
95. Ac-13570
96. Nci60_000023
97. Sbi-0051514.p003
98. Cs-0013897
99. C02078
100. D08526
101. U18409
102. Ab00642548-10
103. Ab00642548-11
104. Ab00642548_12
105. Ab00642548_13
106. A878657
107. Q416154
108. U-18409
109. Actinospectacin; Espectinomicina; Chx-3101
110. Sr-05000001868-4
111. Ethyl2-anilino-4-chloro-5-formyl-3-thiophenecarboxylate
112. (1r,3s,5r,8r,10r,11s,12s,13r,14s)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.0^{3,8}]tetradecan-7-one
113. (2r,4ar,5ar,6s,7s,8r,9s,9ar,10as)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)octahydro-2h-benzo[b]pyrano[2,3-e][1,4]dioxin-4(3h)-one
114. (2r-(2.alpha.,4a.beta.,5a.beta.,6.beta.,7.beta.,8.beta.,9.alpha.,9a.alpha.,10a.beta.))-decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-4h-pyrano(2,3-b)(1,4)benzodioxin-4-one
| Molecular Weight | 332.35 g/mol |
|---|---|
| Molecular Formula | C14H24N2O7 |
| XLogP3 | -3.1 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 2 |
| Exact Mass | 332.15835111 g/mol |
| Monoisotopic Mass | 332.15835111 g/mol |
| Topological Polar Surface Area | 130 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 478 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For use in the treatment of acute gonorrheal urethritis and proctitis in the male and acute gonorrheal cervicitis and proctitis in the female when due to susceptible strains of Neisseria gonorrhoeae.
Spectinomycin is an aminocyclitol antibiotic produced by a species of soil microorganism designated as Streptomyces spectabilis. In vitro studies have shown spectinomycin to be active against most strains of Neisseria gonorrhoeae (minimum inhibitory concentration <7.5 to 20 mcg/mL). Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure.
Anti-Bacterial Agents
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
J - Antiinfectives for systemic use
J01 - Antibacterials for systemic use
J01X - Other antibacterials
J01XX - Other antibacterials
J01XX04 - Spectinomycin
Absorption
Rapidly and almost completely absorbed after intramuscular injection.
1 to 3 hours in patients with normal renal function and 10 to 30 hours in patients with impaired renal function with a creatinine clearance < 20 mL per minute.
Spectinomycin is an inhibitor of protein synthesis in the bacterial cell; the site of action is the 30S ribosomal subunit. It is bactericidal in its action.
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