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2D Structure
Also known as: 71-27-2, Suxamethonium chloride, Succinyldicholine chloride, Anectine, Suxamethonii chloridum, Lysthenon
Molecular Formula
C14H30Cl2N2O4
Molecular Weight
361.3  g/mol
InChI Key
YOEWQQVKRJEPAE-UHFFFAOYSA-L
FDA UNII
I9L0DDD30I

A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium;dichloride
2.1.2 InChI
InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
2.1.3 InChI Key
YOEWQQVKRJEPAE-UHFFFAOYSA-L
2.1.4 Canonical SMILES
C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.[Cl-].[Cl-]
2.2 Other Identifiers
2.2.1 UNII
I9L0DDD30I
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Anectine

2. Bromide, Suxamethonium

3. Celocurine

4. Dibromide, Succinylcholine

5. Dichloride, Succinylcholine

6. Dicholine Succinate

7. Diiodide, Succinylcholine

8. Diperchlorate, Succinylcholine

9. Ditilin

10. Listenon

11. Lysthenon

12. Myorelaxin

13. Quelicin

14. Succicuran

15. Succinate, Dicholine

16. Succinylcholine

17. Succinylcholine Dibromide

18. Succinylcholine Dichloride

19. Succinylcholine Dichloride, Di H2o

20. Succinylcholine Dichloride, Di-h2o

21. Succinylcholine Diiodide

22. Succinylcholine Diperchlorate

23. Succinylcholine Iodide

24. Succinyldicholine

25. Suxamethonium

26. Suxamethonium Bromide

27. Suxamethonium Chloride

2.3.2 Depositor-Supplied Synonyms

1. 71-27-2

2. Suxamethonium Chloride

3. Succinyldicholine Chloride

4. Anectine

5. Suxamethonii Chloridum

6. Lysthenon

7. Midarine

8. Quelicin

9. Scoline

10. Pantolax

11. Suxamethonium Dichloride

12. Chlorsuccinylcholin

13. Succinylcholine Dichloride

14. Succinylforte

15. Lysthenone

16. Succicuran

17. Sucostrin

18. Suxcert

19. Suxinyl

20. Bis(succinyldichlorocholine)

21. Choline Chloride Succinate (2:1)

22. Succinyl-asta

23. Scoline Chloride

24. Cloruro De Suxametonio

25. Anectine Chloride

26. Quelicin Chloride

27. Sucostrin Chloride

28. Chlorure De Succinilcoline

29. 2-dimethylaminoethyl Succinate Dimethochloride

30. Suxamethionium Chloride

31. Listenon

32. Succinoylcholine Chloride

33. Choline, Chloride Succinate

34. Choline Succinate Dichloride

35. Succinyl Bischoline Chloride

36. Succinylbischoline Dichloride

37. (2-hydroxyethyl)trimethylammonium Chloride Succinate

38. I9l0ddd30i

39. Bis(2-dimethylaminoethyl)succinate Bis(methochloride)

40. Suxamethonium Chloride [inn]

41. Chebi:61219

42. Nsc-49132

43. Succinic Acid, Diester With Choline Chloride

44. Ncgc00094357-01

45. Myoplegine

46. Sukolin

47. Succin

48. Dsstox_cid_3603

49. Diacetylcholine Dichloride

50. Dsstox_rid_77103

51. Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(n,n,n-trimethyl-), Dichloride

52. Trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium;dichloride

53. Dsstox_gsid_23603

54. Suxamethonium Chloride (inn)

55. Succinyldicholine Dichloride

56. Succamethonium Chloratum

57. Quelicin Preservative Free

58. 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(n,n,n-trimethylethanaminium) Dichloride

59. Cas-71-27-2

60. Chlorsuccinylcholin [german]

61. Sukcinylcholinchlorid [czech]

62. Sukcinylcholinchlorid

63. Succinilcolina Cloruro [dcit]

64. Choline, Succinyl-, Dichloride

65. Succinilcolina Cloruro

66. Succinylcholine Chloride [usan]

67. Chlorure De Succinilcoline [french]

68. Cloruro Di Succinilcolina

69. Cloruro Di Succinilcolina [italian]

70. Suxamethonii Chloridum [inn-latin]

71. Einecs 200-747-4

72. Nsc 49132

73. Cloruro De Suxametonio [inn-spanish]

74. Unii-i9l0ddd30i

75. Ai3-51679

76. Anectine (tn)

77. Quelicin (tn)

78. Choline, Chloride, Succinate (2:1)

79. Mfcd00038725

80. Succinylcholine Chloride [usan:usp]

81. Suxamethone

82. Choline, Hydroxide, Succinate (2:1), Dihydrochloride

83. Succinyl-bis(n-(2-oxyethyl)trimethylammonium)-dichlorid

84. 3,8-dioxa-4,7-dioxodercan-1,10-bis(trimethylammonium)dichlorid

85. Succinic Acid, Bis(beta-dimethylaminoethyl) Ester, Dimethochloride

86. Chembl983

87. Schembl41536

88. Anhydrous Suxamethonium Chloride

89. Succinylcholine Chloride (usp)

90. Dtxsid1023603

91. Anhydrous Succinylcholine Chloride

92. Suxamethonium Chloride (anhydrous)

93. Hms3263g22

94. Anhydrous Succinylcholine Dichloride

95. Succinylcholine Chloride (anhydrous)

96. Tox21_111268

97. Tox21_501080

98. Anhydrous Succinyldicholine Dichloride

99. Succinylcholine Chloride [mi]

100. Succinylcholine Dichloride (anhydrous)

101. Akos015961173

102. Suxamethonium Chloride [mart.]

103. Tox21_111268_1

104. Ac-4688

105. Ccg-222384

106. Lp01080

107. Suxamethonium Chloride [who-dd]

108. Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(n,n,n-trimethyl-, Dichloride

109. Succinylcholine Chloride [vandf]

110. Succinyldicholine Dichloride (anhydrous)

111. Ncgc00015971-05

112. Ncgc00261765-01

113. Succinylcholine Chloride [usp-rs]

114. Db-055512

115. Eu-0101080

116. Suxamethonium Chloride [ep Monograph]

117. Succinylcholine Chloride [orange Book]

118. D00766

119. S 8251

120. Succinylcholine Chloride [usp Monograph]

121. Sr-01000075346

122. Q-201750

123. Sr-01000075346-2

124. Q12455154

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 361.3 g/mol
Molecular Formula C14H30Cl2N2O4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count11
Exact Mass360.1582628 g/mol
Monoisotopic Mass360.1582628 g/mol
Topological Polar Surface Area52.6 Ų
Heavy Atom Count22
Formal Charge0
Complexity284
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameQuelicin preservative free
Active IngredientSuccinylcholine chloride
Dosage FormInjectable
RouteInjection
Strength20mg/ml; 100mg/ml
Market StatusPrescription
CompanyHospira

2 of 2  
Drug NameQuelicin preservative free
Active IngredientSuccinylcholine chloride
Dosage FormInjectable
RouteInjection
Strength20mg/ml; 100mg/ml
Market StatusPrescription
CompanyHospira

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Neuromuscular Depolarizing Agents

Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation. (See all compounds classified as Neuromuscular Depolarizing Agents.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Neuromuscular Depolarizing Blockade [PE]; Depolarizing Neuromuscular Blocker [EPC]