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Technical details about Sulforidazine, learn more about the structure, uses, toxicity, action, side effects and more

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2D Structure
1. Also known as: Imagotan, Psychoson, Inofal, 14759-06-9, Thioridazine 2-sulfone, Thioridazine-2-sulfone
Molecular Formula
C21H26N2O2S2
Molecular Weight
402.6  g/mol
InChI Key
FLGCRGJDQJIJAW-UHFFFAOYSA-N
FDA UNII
B7599I244X

sulforidazine is a natural product found in Aspergillus fumigatus with data available.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfonylphenothiazine
2.1.2 InChI
InChI=1S/C21H26N2O2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)26-21-11-10-17(15-19(21)23)27(2,24)25/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
2.1.3 InChI Key
FLGCRGJDQJIJAW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)C
2.2 Other Identifiers
2.2.1 UNII
B7599I244X
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Imagotan

2. Psychoson

3. Inofal

4. 14759-06-9

5. Thioridazine 2-sulfone

6. Thioridazine-2-sulfone

7. Tpn-12

8. Thioridazine Sulfone

9. Thioridazine Sulphone

10. 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonylphenothiazine

11. 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfonylphenothiazine

12. 10h-phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-

13. B7599i244x

14. Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonyl-

15. Solforidazina [dcit]

16. Solforidazina

17. Sulforidazina

18. Sulforidazinum

19. Tpn 12

20. Sulforidazine [inn:dcf]

21. 10h-phenothiazine, 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfonyl)-

22. Sulforidazinum [inn-latin]

23. Sulforidazina [inn-spanish]

24. Einecs 238-818-7

25. Brn 1230366

26. 2-methylsulfonyl-10-[2-(1-methyl-2-piperidyl)ethyl]phenothiazine

27. (+/-)-thioridazine-2-sulfone

28. 2-methylsulfonyl-10-(2-(1-methyl-2-piperidyl)ethyl)phenothiazine

29. Unii-b7599i244x

30. 2-methylsulfonyl-10-(2-(1-methyl-2-piperidyl)ethyl)phenothiazin

31. Sulforidazine [mi]

32. Sulforidazine [inn]

33. Schembl145025

34. Sulforidazine [mart.]

35. Sulforidazine [who-dd]

36. Chembl2107268

37. Bdbm86723

38. Dtxsid30864531

39. Chebi:135644

40. Nsc_31765

41. Akos030239787

42. Cas_14759-06-9

43. Ft-0675190

44. Thioridazine Impurity E [ep Impurity]

45. L000789

46. J-008369

47. Q7636215

48. Thioridazine Hydrochloride Impurity E [ep Impurity]

49. 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-methylsulfonylphenothiazine

50. 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfonyl)-10h-phenothiazine

51. 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-10h-phenothiazine #

52. 2-methanesulfonyl-10-[2-(1-methylpiperidin-2-yl)ethyl]-10h-phenothiazine

53. Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylsulfonyl)-

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 402.6 g/mol
Molecular Formula C21H26N2O2S2
XLogP34.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass402.14357042 g/mol
Monoisotopic Mass402.14357042 g/mol
Topological Polar Surface Area74.3 Ų
Heavy Atom Count27
Formal Charge0
Complexity606
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antidepressive Agents

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)


Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


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