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    Sulforidazine

    INTERMEDIATES

    PharmaCompass
    Xls

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    2D Structure
    Also known as: Imagotan, Psychoson, Inofal, 14759-06-9, Thioridazine 2-sulfone, Thioridazine-2-sulfone
    Molecular Formula
    C21H26N2O2S2
    Molecular Weight
    402.6  g/mol
    InChI Key
    FLGCRGJDQJIJAW-UHFFFAOYSA-N
    FDA UNII
    B7599I244X
    sulforidazine is a natural product found in Aspergillus fumigatus with data available.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfonylphenothiazine
    2.1.2 InChI
    InChI=1S/C21H26N2O2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)26-21-11-10-17(15-19(21)23)27(2,24)25/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
    2.1.3 InChI Key
    FLGCRGJDQJIJAW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)C
    2.2 Other Identifiers
    2.2.1 UNII
    B7599I244X
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Imagotan

    2. Psychoson

    3. Inofal

    4. 14759-06-9

    5. Thioridazine 2-sulfone

    6. Thioridazine-2-sulfone

    7. Tpn-12

    8. Thioridazine Sulfone

    9. Thioridazine Sulphone

    10. 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonylphenothiazine

    11. 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfonylphenothiazine

    12. 10h-phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-

    13. B7599i244x

    14. Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonyl-

    15. Solforidazina [dcit]

    16. Solforidazina

    17. Sulforidazina

    18. Sulforidazinum

    19. Tpn 12

    20. Sulforidazine [inn:dcf]

    21. 10h-phenothiazine, 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfonyl)-

    22. Sulforidazinum [inn-latin]

    23. Sulforidazina [inn-spanish]

    24. Einecs 238-818-7

    25. Brn 1230366

    26. 2-methylsulfonyl-10-[2-(1-methyl-2-piperidyl)ethyl]phenothiazine

    27. (+/-)-thioridazine-2-sulfone

    28. 2-methylsulfonyl-10-(2-(1-methyl-2-piperidyl)ethyl)phenothiazine

    29. Unii-b7599i244x

    30. 2-methylsulfonyl-10-(2-(1-methyl-2-piperidyl)ethyl)phenothiazin

    31. Sulforidazine [mi]

    32. Sulforidazine [inn]

    33. Schembl145025

    34. Sulforidazine [mart.]

    35. Sulforidazine [who-dd]

    36. Chembl2107268

    37. Bdbm86723

    38. Dtxsid30864531

    39. Chebi:135644

    40. Nsc_31765

    41. Akos030239787

    42. Cas_14759-06-9

    43. Ft-0675190

    44. Thioridazine Impurity E [ep Impurity]

    45. L000789

    46. J-008369

    47. Q7636215

    48. Thioridazine Hydrochloride Impurity E [ep Impurity]

    49. 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-methylsulfonylphenothiazine

    50. 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfonyl)-10h-phenothiazine

    51. 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-10h-phenothiazine #

    52. 2-methanesulfonyl-10-[2-(1-methylpiperidin-2-yl)ethyl]-10h-phenothiazine

    53. Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylsulfonyl)-

    2.4 Create Date
    2005-03-27
    3 Chemical and Physical Properties
    Molecular Weight 402.6 g/mol
    Molecular Formula C21H26N2O2S2
    XLogP34.6
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count4
    Exact Mass402.14357042 g/mol
    Monoisotopic Mass402.14357042 g/mol
    Topological Polar Surface Area74.3 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity606
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antidepressive Agents

    Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

    Antipsychotic Agents

    Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)