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    Sulthiame

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

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    2D Structure
    Also known as: Sulthiame, 61-56-3, Ospolot, Trolone, Sultiam, Sulphenyltame
    Molecular Formula
    C10H14N2O4S2
    Molecular Weight
    290.4  g/mol
    InChI Key
    HMHVCUVYZFYAJI-UHFFFAOYSA-N
    FDA UNII
    I00Q766CZ2
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide
    2.1.2 InChI
    InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16)
    2.1.3 InChI Key
    HMHVCUVYZFYAJI-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CCS(=O)(=O)N(C1)C2=CC=C(C=C2)S(=O)(=O)N
    2.2 Other Identifiers
    2.2.1 UNII
    I00Q766CZ2
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Ospolot

    2. P-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide, S,s-dioxide

    3. Sulthiame

    4. Sultiam

    2.3.2 Depositor-Supplied Synonyms

    1. Sulthiame

    2. 61-56-3

    3. Ospolot

    4. Trolone

    5. Sultiam

    6. Sulphenyltame

    7. Sulthiamine

    8. Conadil

    9. Contravul

    10. Riker 594

    11. Sultiamum

    12. Elisal

    13. Bayer A-168

    14. Sulthiame [usan]

    15. 4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide

    16. 4-(1,1-dioxido-1,2-thiazinan-2-yl)benzenesulfonamide

    17. Sultiame [inn]

    18. Rp-10284

    19. P-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide, S,s-dioxide

    20. Benzenesulfonamide, 4-(tetrahydro-2h-1,2-thiazin-2-yl)-, S,s-dioxide

    21. R-594

    22. Riker-594

    23. Chembl328560

    24. 2-(p-sulfamoylphenyl)-tetrahydro-2h-1,2-thiazine 1,1-dioxide

    25. Chebi:32171

    26. 2h-1,2-thiazine, Tetrahydro-2-(p-sulfamoylphenyl)-, 1,1-dioxide

    27. I00q766cz2

    28. Sulthiame (usan)

    29. Benzenesulfonamide, P-(tetrahydro-2h-1,2-thiazin-2-yl)-, Dioxide

    30. Sultiamo

    31. Sultiamum [inn-latin]

    32. Sultiamo [inn-spanish]

    33. Einecs 200-511-0

    34. Brn 1222219

    35. Rp 10284

    36. Unii-i00q766cz2

    37. Sulthiame, 2

    38. Sulthiame (slt)

    39. 2-(4-sulfamoylphenyl)-1,2-thiazixan 1,1-dioxid

    40. Ospolot (tn)

    41. Sultiame (jp17)

    42. 2q1q

    43. Sulthiame [mi]

    44. Sultiame [jan]

    45. Dsstox_cid_3626

    46. Sultiame [mart.]

    47. Sultiame [who-dd]

    48. Dsstox_rid_97552

    49. Dsstox_gsid_23626

    50. Oprea1_326703

    51. Schembl38898

    52. Zinc2119

    53. Dtxsid4023626

    54. Bdbm26999

    55. Hms3746a19

    56. Bcp30158

    57. Tox21_113683

    58. 4-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide S,s-dioxide

    59. Cs-7868

    60. Db08329

    61. Cas-61-56-3

    62. Sultiame 100 Microg/ml In Acetonitrile

    63. Ncgc00249907-01

    64. As-83082

    65. Hy-108316

    66. Ft-0674777

    67. D01787

    68. Q2364943

    69. 4-(1,1-dioxido-1,2-thiazinan-2-yl)benzenesulfonamide #

    70. 4-(1,1-dioxo-1i>>6-[1,2]thiazinan-2-yl)-benzenesulfonamide

    71. P-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide Dioxide

    72. 4-(1,1-dioxo-1$l^{6},2-thiazinan-2-yl)benzene-1-sulfonamide

    73. 4-(tetrahydro-1,1-dioxido-2h-1,2-thiazin-2-yl)benzenesulfonamide

    74. 4-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide, S,s-dioxide

    75. Osp

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 290.4 g/mol
    Molecular Formula C10H14N2O4S2
    XLogP30.1
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count2
    Exact Mass290.03949928 g/mol
    Monoisotopic Mass290.03949928 g/mol
    Topological Polar Surface Area114 Ų
    Heavy Atom Count18
    Formal Charge0
    Complexity481
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anticonvulsants

    Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)

    4.2 ATC Code

    N - Nervous system

    N03 - Antiepileptics

    N03A - Antiepileptics

    N03AX - Other antiepileptics

    N03AX03 - Sultiame