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Technical details about Technetium-99, learn more about the structure, uses, toxicity, action, side effects and more

Technetium-99

Synopsis, Chemistry

DOSSIERs // Finished Dosage Forms

14 Dossiers, 13 FDA Orange Book, 1 Canada

DRUG PRODUCT COMPOSITION

INJECTABLE;INJECTION - N/A, INJECTABLE;INJECTION - N/A

PATENTS

2 US Patents, 1 US Exclusivities

1. Also known as: Technetium-99, Technetium-99m, Technetium-99mtc, Technetium, isotope of mass 99, 99tc, Technetium 99m

Molecular Formula

Molecular Weight

98.906250 g/mol

InChI Key

GKLVYJBZJHMRIY-OUBTZVSYSA-N

FDA UNII

6EW75241VU

Technetium TC-99m is one of the radioactive isotopes of technetium, a gamma/beta-emitter with a half life of 6 hours.

1 2D Structure

2D Structure

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

technetium-99

2.1.2 InChI

InChI=1S/Tc/i1+1

2.1.3 InChI Key

GKLVYJBZJHMRIY-OUBTZVSYSA-N

2.1.4 Canonical SMILES

[Tc]

2.1.5 Isomeric SMILES

[99Tc]

2.2 Other Identifiers

2.2.1 UNII

6EW75241VU

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 99tc Radioisotope

2. Tc-99 Radioisotope

3. Technetium-99

2.3.2 Depositor-Supplied Synonyms

1. Technetium-99

2. Technetium-99m

3. Technetium-99mtc

4. Technetium, Isotope Of Mass 99

5. 99tc

6. Technetium 99m

7. 14133-76-7

8. Tc 99

9. Technetium Tc 99m

10. Technetium (99mtc)

11. Technetium, Tc-99m

12. Technetium (tc 99m)

13. 6ew75241vu

14. Cea-scan

15. Arcitumomab Technetium-99m

16. Technetium-99m Arcitumomab

17. Unii-029jf1scu8

18. Technegas

19. Technetium Tc 99m Arcitumomab

20. Unii-6ew75241vu

21. Cea Scan

22. Technetium,tc-99m

23. Tc-99m Arcitumomab

24. Arcitumomab 99mtc-labeled Form [mi]

25. Technetium-99m Arcitumomab [who-dd]

26. Technetium 99m Metal

27. 029jf1scu8

28. Arcitumomab 99mtc-labeled Form

29. Technetium (99mtc) Arcitumomab

30. (99)tc

31. Chebi:33371

32. Dtxsid00874006

33. Technetium Tc 99m [vandf]

34. Technetium,tc-99m [vandf]

35. Arcitumomab, Technetium-99m Labeled

36. (99)43tc

37. Technetium Tc 99m [who-dd]

38. Technetium (99mtc) Technegas

39. Db14227

40. Technetium (tc 99m) [vandf]

41. 154361-49-6

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	Tc
Molecular Weight	98.906250 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	0
Rotatable Bond Count	0
Exact Mass	98.906250 g/mol
Monoisotopic Mass	98.906250 g/mol
Topological Polar Surface Area	0 Å²
Heavy Atom Count	1
Formal Charge	0
Complexity	0
Isotope Atom Count	1
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

CEA-Scan is indicated only in patients with histologically-demonstrated carcinoma of the colon or rectum for imaging of recurrence and/or metastases. CEA-Scan is employed for diagnostic use only, in the above mentioned patients, as an adjunct to standard non-invasive imaging techniques, such as ultrasonography or CT scan, in the following situations:

- Patients with evidence of recurrence and/or metastatic carcinoma of the colon or rectum, who are undergoing an evaluation for extent of disease, such as prior to surgical resection and/or other therapy, or

- Patients with suspected recurrence and/or metastatic carcinoma of the colon or rectum in association with rising levels of carcinoembryonic antigen (CEA).

5 Pharmacology and Biochemistry

5.1 ATC Code

V09IA01

V - Various

V09 - Diagnostic radiopharmaceuticals

V09E - Respiratory system

V09EA - Technetium (99mtc), inhalants

V09EA02 - Technetium (99mTc) technegas

V - Various

V09 - Diagnostic radiopharmaceuticals

V09I - Tumour detection

V09IA - Technetium (99mtc) compounds

V09IA06 - Technetium (99mTc) arcitumomab

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