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    Terbutaline Sulphate

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    DIGITAL CONTENT

    GLOBAL SALES INFORMATION

    MARKET PLACE

    REF. STANDARDS & IMPURITIES

    PharmaCompass
    $ API Ref.Price (USD/KG) : 400Xls

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    2D Structure
    Also known as: Bricanyl, Terbutaline hemisulfate, Tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium;sulfate, Bricanyl turbuhaler, 576pu70y8e, 1,3-benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, sulfate (2:1) (salt)
    Molecular Formula
    C24H40N2O10S
    Molecular Weight
    548.6  g/mol
    InChI Key
    KFVSLSTULZVNPG-UHFFFAOYSA-N
    A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium;sulfate
    2.1.2 InChI
    InChI=1S/2C12H19NO3.H2O4S/c2*1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8;1-5(2,3)4/h2*4-6,11,13-16H,7H2,1-3H3;(H2,1,2,3,4)
    2.1.3 InChI Key
    KFVSLSTULZVNPG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)(C)[NH2+]CC(C1=CC(=CC(=C1)O)O)O.CC(C)(C)[NH2+]CC(C1=CC(=CC(=C1)O)O)O.[O-]S(=O)(=O)[O-]
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Arubendol

    2. Asthmoprotect

    3. Brethine

    4. Bricanyl

    5. Bricanyl Sa

    6. Butaliret

    7. Butalitab

    8. Contimit

    9. Kwd 2019

    10. Kwd-2019

    11. Kwd2019

    12. Monovent

    13. Taziken

    14. Tedipulmo

    15. Terbasmin

    16. Terbul

    17. Terbutalin Al

    18. Terbutalin Ratiopharm

    19. Terbutalin Stada

    20. Terbutalin Von Ct

    21. Terbutalin-ratiopharm

    22. Terbutaline

    23. Terbutaline Sulfate

    24. Terbuturmant

    2.2.2 Depositor-Supplied Synonyms

    1. Bricanyl

    2. Terbutaline Hemisulfate

    3. Tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium;sulfate

    4. Bricanyl Turbuhaler

    5. 576pu70y8e

    6. 1,3-benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, Sulfate (2:1) (salt)

    7. Einecs 245-386-3

    8. Unii-576pu70y8e

    9. 1-(3,5-dihydroxyphenyl)-2-tert-butylaminoethanol Sulphate

    10. Terbutaline Sulfate [usan:usp:jan]

    11. Nsc 757336

    12. (+-)-alpha-((tert-butylamino)methyl)-3,5-dihydroxybenzyl Alcohol Sulfate (2:1) (salt)

    13. Benzyl Alcohol, Alpha-((tert-butylamino)methyl)-3,5-dihydroxy-, Sulfate (2:1)

    2.3 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 548.6 g/mol
    Molecular Formula C24H40N2O10S
    Hydrogen Bond Donor Count8
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count8
    Exact Mass548.24036665 g/mol
    Monoisotopic Mass548.24036665 g/mol
    Topological Polar Surface Area243 Ų
    Heavy Atom Count37
    Formal Charge0
    Complexity267
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count2
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameTerbutaline sulfate
    Drug LabelTerbutaline Sulfate, USP, the active ingredient of Terbutaline Sulfate Injection, USP, is a betaadrenergic agonist bronchodilator available as a sterile, nonpyrogenic, aqueous solution in vials, for subcutaneous administration. Each milliliter of...
    Active IngredientTerbutaline sulfate
    Dosage FormTablet; Injectable
    RouteInjection; Oral
    Strength2.5mg; 1mg/ml; 5mg
    Market StatusPrescription
    CompanyBedford; Hikma Farmaceutica; United Biomedcl; Fresenius Kabi Usa; Lannett; Impax Labs; Akorn

    2 of 2  
    Drug NameTerbutaline sulfate
    Drug LabelTerbutaline Sulfate, USP, the active ingredient of Terbutaline Sulfate Injection, USP, is a betaadrenergic agonist bronchodilator available as a sterile, nonpyrogenic, aqueous solution in vials, for subcutaneous administration. Each milliliter of...
    Active IngredientTerbutaline sulfate
    Dosage FormTablet; Injectable
    RouteInjection; Oral
    Strength2.5mg; 1mg/ml; 5mg
    Market StatusPrescription
    CompanyBedford; Hikma Farmaceutica; United Biomedcl; Fresenius Kabi Usa; Lannett; Impax Labs; Akorn

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Adrenergic beta-2 Receptor Agonists

    Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS. (See all compounds classified as Adrenergic beta-2 Receptor Agonists.)

    Sympathomimetics

    Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

    Tocolytic Agents

    Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete. (See all compounds classified as Tocolytic Agents.)

    Bronchodilator Agents

    Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)