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    Technical details about Terizidone, learn more about the structure, uses, toxicity, action, side effects and more

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    Terizidone

    APIs // Active Pharmaceutical Ingredients

    PRICE INFORMATION

    DOSSIERs // Finished Dosage Forms

    MARKET PLACE

    PharmaCompass

    Farmhispania Group, a leading European CDMO in HPAPI Technologies & High Potency Fermentation.

    One Pharma aims to be one of the leading generic companies in Europe.

    2D Structure
    1. Also known as: 25683-71-0, Terizidonum, Terizidone [inn], 1199lex5n8, Terizidone (inn), 4,4'-(((1e,1'e)-1,4-phenylenebis(methanylylidene))bis(azanylylidene))bis(isoxazolidin-3-one)
    Molecular Formula
    C14H14N4O4
    Molecular Weight
    302.29  g/mol
    InChI Key
    ODKYYBOHSVLGNU-UHFFFAOYSA-N
    FDA UNII
    1199LEX5N8
    Terizidone is a broad spectrum antibiotic used as a second-line antitubercular drug, effective against pulmonary and extrapulmonary tuberculosis. Terizidone has activity against Mycobacterium strains that are resistant to first-line drugs.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[[4-[(3-oxo-1,2-oxazolidin-4-yl)iminomethyl]phenyl]methylideneamino]-1,2-oxazolidin-3-one
    2.1.2 InChI
    InChI=1S/C14H14N4O4/c19-13-11(7-21-17-13)15-5-9-1-2-10(4-3-9)6-16-12-8-22-18-14(12)20/h1-6,11-12H,7-8H2,(H,17,19)(H,18,20)
    2.1.3 InChI Key
    ODKYYBOHSVLGNU-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1C(C(=O)NO1)N=CC2=CC=C(C=C2)C=NC3CONC3=O
    2.2 Other Identifiers
    2.2.1 UNII
    1199LEX5N8
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 4,4'-(p-phenylenebis(methyleneimino))bis-3-isoxazolidone

    2. Terazolidone

    3. Terivalidin

    4. Terivalidine

    5. Terizidon

    6. Terizidone, Calcium Salt, (r-(r*,r*))-isomer

    2.3.2 Depositor-Supplied Synonyms

    1. 25683-71-0

    2. Terizidonum

    3. Terizidone [inn]

    4. 1199lex5n8

    5. Terizidone (inn)

    6. 4,4'-(((1e,1'e)-1,4-phenylenebis(methanylylidene))bis(azanylylidene))bis(isoxazolidin-3-one)

    7. 4-[[4-[(3-oxo-1,2-oxazolidin-4-yl)iminomethyl]phenyl]methylideneamino]-1,2-oxazolidin-3-one

    8. Terizidona

    9. 4,4'-(p-phenylenebis(methyleneamino))di-(isoxazolidin-3-one)

    10. Terizidonum [inn-latin]

    11. Terizidona [inn-spanish]

    12. Unii-1199lex5n8

    13. Terivalidin (tn)

    14. Einecs 247-186-1

    15. D-terizidone

    16. Terizidone [mart.]

    17. Terizidone [who-dd]

    18. Schembl193690

    19. Fmoc-d-3-(2-furyl)-alanine

    20. Chembl2107553

    21. Dtxsid30865245

    22. Dtxsid70905098

    23. Chebi:135278

    24. 4,4'-[1,4-phenylenebis(methylidynenitrilo)]bis-3-isoxazolidinone

    25. Bcp15839

    26. Mfcd00866818

    27. Akos025311219

    28. Db12954

    29. As-16056

    30. Hy-112324

    31. Cs-0045228

    32. Ft-0674867

    33. C13574

    34. D07247

    35. A911347

    36. Q1318344

    37. 4,4'-[1,4-phenylenebis(methanylylideneazanylylidene)]di(1,2-oxazolidin-3-one)

    38. 4,4'-((1e,1'e)-(1,4-phenylenebis(methanylylidene))bis(azanylylidene))bis(isoxazolidin-3-one)

    39. 4,4'-(1e,1'e)-(1,4-phenylenebis(methan-1-yl-1-ylidene))bis(azan-1-yl-1-ylidene)diisoxazolidin-3-one

    40. 6819-23-4

    2.4 Create Date
    2005-08-01
    3 Chemical and Physical Properties
    Molecular Weight 302.29 g/mol
    Molecular Formula C14H14N4O4
    XLogP3-0.2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count4
    Exact Mass302.10150494 g/mol
    Monoisotopic Mass302.10150494 g/mol
    Topological Polar Surface Area101 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity441
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count2
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 ATC Code

    J - Antiinfectives for systemic use

    J04 - Antimycobacterials

    J04A - Drugs for treatment of tuberculosis

    J04AK - Other drugs for treatment of tuberculosis

    J04AK03 - Terizidone

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