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2D Structure
Also known as: Myolastan, Musaril, Clinoxan, 10379-14-3, Cb 4261, Ro 06-6657
Molecular Formula
C16H17ClN2O
Molecular Weight
288.77  g/mol
InChI Key
IQWYAQCHYZHJOS-UHFFFAOYSA-N
FDA UNII
FO92091VP8

1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one
2.1.2 InChI
InChI=1S/C16H17ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h5,7-9H,2-4,6,10H2,1H3
2.1.3 InChI Key
IQWYAQCHYZHJOS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CCCCC3
2.2 Other Identifiers
2.2.1 UNII
FO92091VP8
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4621 Cb

2. Mobiforton

3. Mtw-tetrazepam

4. Musapam

5. Musaril

6. Myolastan

7. Myospasmal

8. Panos

9. Rilex

10. Tethexal

11. Tetra-saar

12. Tetramdura

13. Tetrarelax

14. Tetrazep 1a Pharma

15. Tetrazep Abz

16. Tetrazep Von Ct

2.3.2 Depositor-Supplied Synonyms

1. Myolastan

2. Musaril

3. Clinoxan

4. 10379-14-3

5. Cb 4261

6. Ro 06-6657

7. 4261 Cb

8. 7-chloro-5-(cyclohexen-1-yl)-1,3-dihydro-1-methyl-2h-1,4-benzodiazepin-2-one

9. 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(1-cyclohexen-1-yl)-1,3-dihydro-1-methyl-

10. Fo92091vp8

11. Tetrazepam (inn)

12. 7-chloro-5-(1-cyclohexenyl)-1-methyl-2-oxo-2,3-dihydro-1h-(1,4)-benzo(f)diazepine

13. Cb-4261

14. Tetrazepam [inn]

15. 7-chloro-5-(cyclohexen-1-yl)-1-methyl-3h-1,4-benzodiazepin-2-one

16. Tetrazepamum

17. Tetrazepamum [inn-latin]

18. Tetrazepam [inn:ban:dcf]

19. Einecs 233-837-7

20. Brn 0890548

21. Unii-fo92091vp8

22. Dea No. 2886

23. Myolastan (tn)

24. Tetrazepam [mi]

25. Tetrazepam [mart.]

26. Tetrazepam [who-dd]

27. 5-24-04-00064 (beilstein Handbook Reference)

28. Schembl157998

29. Zinc2144

30. Chembl2105527

31. Dtxsid00146058

32. Tetrazepam [ep Monograph]

33. Chebi:135198

34. Tetrazepam 0.1 Mg/ml In Methanol

35. Cs-6656

36. Db13324

37. 7-chloro-5-(1-cyclohexen-1- Yl)-1,3-dihydro-1-methyl-2h-1,4-benzodiazepin-2-one

38. Hy-101615

39. D07277

40. Q421104

41. 7-chloro-5-(1-cyclohexen-1-yl)-1-methyl-1,3-dihydro-2h-1,4-benzodiazepin-2-one #

42. 7-chloro-5-(cyclohex-1-en-1-yl)-1-methyl-1,3-dihydro-2h-benzo[e][1,4]diazepin-2-one

43. 7-chloro-5-(cyclohex-1-en-1-yl)-1-methyl-2,3-dihydro-1h-1,4-benzodiazepin-2-one

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 288.77 g/mol
Molecular Formula C16H17ClN2O
XLogP33.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass288.1029409 g/mol
Monoisotopic Mass288.1029409 g/mol
Topological Polar Surface Area32.7 Ų
Heavy Atom Count20
Formal Charge0
Complexity457
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Muscle Relaxants, Central

A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358) (See all compounds classified as Muscle Relaxants, Central.)


4.2 ATC Code

M - Musculo-skeletal system

M03 - Muscle relaxants

M03B - Muscle relaxants, centrally acting agents

M03BX - Other centrally acting agents

M03BX07 - Tetrazepam