Please Wait
Applying Filters...
menu
    • menu
    Evonik

    Virtual Booth

    Contact Supplier

    Sharp is a global leader in pharmaceutical packaging and clinical trial supply services.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2025-04-21

    Virtual Booth

    Contact Supplier

    Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

    Virtual Booth

    Contact Supplier

    USP reference standards; highly characterized specimens of drug substances, impurities, excipients, degradation products & more.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2025-04-14

    Virtual Booth

    Contact Supplier

    Menu

    Tripelennamine Citrate

    FINISHED DOSAGE FORMULATIONS

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 6138-56-3, Tripelennamine (citrate), Nsc-757360, 2-(benzyl(2-(dimethylamino)ethyl)amino)pyridine citrate (1:1), 30oc46a3j9, 1,2-ethanediamine, n,n-dimethyl-n'-(phenylmethyl)-n'-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
    Molecular Formula
    C22H29N3O7
    Molecular Weight
    447.5  g/mol
    InChI Key
    GGRBYIUPUOYRLQ-UHFFFAOYSA-N
    FDA UNII
    30OC46A3J9
    A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine;2-hydroxypropane-1,2,3-tricarboxylic acid
    2.1.2 InChI
    InChI=1S/C16H21N3.C6H8O7/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-11H,12-14H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
    2.1.3 InChI Key
    GGRBYIUPUOYRLQ-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN(C)CCN(CC1=CC=CC=C1)C2=CC=CC=N2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
    2.2 Other Identifiers
    2.2.1 UNII
    30OC46A3J9
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Azaron

    2. Histantin

    3. Pyribenzamine

    4. Tripelennamine

    5. Tripelennamine Citrate (1:1)

    6. Tripelennamine Hydrochloride

    7. Tripelennamine Maleate

    8. Tripelennamine Maleate (1:1)

    9. Tripelennamine Monohydrochloride

    10. Vetibenzamin

    2.3.2 Depositor-Supplied Synonyms

    1. 6138-56-3

    2. Tripelennamine (citrate)

    3. Nsc-757360

    4. 2-(benzyl(2-(dimethylamino)ethyl)amino)pyridine Citrate (1:1)

    5. 30oc46a3j9

    6. 1,2-ethanediamine, N,n-dimethyl-n'-(phenylmethyl)-n'-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

    7. Ncgc00095775-01

    8. Dsstox_cid_25989

    9. Dsstox_rid_81276

    10. Dsstox_gsid_45989

    11. N'-benzyl-n,n-dimethyl-n'-pyridin-2-ylethane-1,2-diamine;2-hydroxypropane-1,2,3-tricarboxylic Acid

    12. Pyribenzamine Citrate

    13. Cas-6138-56-3

    14. Einecs 228-121-6

    15. Tripelennamine Citrate [usp]

    16. Unii-30oc46a3j9

    17. Pbz (tn)

    18. Schembl99166

    19. Spectrum1500597

    20. Chembl1200769

    21. Dtxsid8045989

    22. Hms501k16

    23. Hms2092a14

    24. Pharmakon1600-01500597

    25. Tripelennamine Citrate [mi]

    26. Tox21_111518

    27. Ccg-39053

    28. Hy-17428b

    29. Nsc757360

    30. Pyridine, 2-(benzyl(2-(dimethylamino)ethyl)amino)-, Citrate (1:1)

    31. Tripelennamine Citrate [vandf]

    32. Tox21_111518_1

    33. Tripelennamine Citrate [mart.]

    34. Nsc 757360

    35. Tripelennamine Citrate [who-dd]

    36. Ncgc00018125-05

    37. Ncgc00095775-02

    38. Tripelennamine Citrate [orange Book]

    39. Cs-0030834

    40. D06246

    41. Sr-01000003013-4

    42. Q27255968

    43. 1,2-ethanediamine, N,n-dimethyl-n'-(phenylmethyl)-n'-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt)

    44. 1,2-ethanediamine, N1,n1-dimethyl-n2-(phenylmethyl)-n2-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

    45. N\'-benzyl-n,n-dimethyl-n\'-pyridin-2-ylethane-1,2-diamine,2-hydroxypropane-1,2,3-tricarboxylic Acid

    2.4 Create Date
    2005-08-09
    3 Chemical and Physical Properties
    Molecular Weight 447.5 g/mol
    Molecular Formula C22H29N3O7
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count11
    Exact Mass447.20055027 g/mol
    Monoisotopic Mass447.20055027 g/mol
    Topological Polar Surface Area152 Ų
    Heavy Atom Count32
    Formal Charge0
    Complexity464
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Allergic Agents

    Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)

    Histamine H1 Antagonists

    Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)