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    Xylazine Hydrochloride

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

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    2D Structure
    Also known as: 23076-35-9, Xylazine hcl, N-(2,6-dimethylphenyl)-5,6-dihydro-4h-1,3-thiazin-2-amine hydrochloride, Celactal, Rompun, Bay 1470 hydrochloride
    Molecular Formula
    C12H17ClN2S
    Molecular Weight
    256.80  g/mol
    InChI Key
    QYEFBJRXKKSABU-UHFFFAOYSA-N
    FDA UNII
    NGC3S0882S
    An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine;hydrochloride
    2.1.2 InChI
    InChI=1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H
    2.1.3 InChI Key
    QYEFBJRXKKSABU-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=C(C(=CC=C1)C)NC2=NCCCS2.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    NGC3S0882S
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Bay Va 1470

    2. Bay-va 1470

    3. Bayva 1470

    4. Rompun

    5. Xylaxine

    6. Xylazin

    7. Xylazine

    8. Xylazine Monohydrochloride

    9. Xylazine Phosphate (1:1)

    2.3.2 Depositor-Supplied Synonyms

    1. 23076-35-9

    2. Xylazine Hcl

    3. N-(2,6-dimethylphenyl)-5,6-dihydro-4h-1,3-thiazin-2-amine Hydrochloride

    4. Celactal

    5. Rompun

    6. Bay 1470 Hydrochloride

    7. Xylazine Chloride

    8. Bay Va 1470

    9. Tranquived

    10. Xylamed

    11. Xylazin Hydrochloride

    12. Anased

    13. Xylazine (hydrochloride)

    14. Bay-va 1470

    15. Xylazine.hcl

    16. N-(2,6-dimethylphenyl)-5,6-dihydro-4h-1,3-thiazin-2-amine;hydrochloride

    17. Mfcd00058196

    18. 5,6-dihydro-2-(2,6-xylidino)-4h-1,3-thiazine Hydrochloride

    19. 5,6-dihydro-2-(2,6-xylidino)-4h-1,3-thiazine Monohydrochloride

    20. Ngc3s0882s

    21. Bay-va-1470

    22. 2-(2,6-dimethylphenylamino)-4h-5,6-dihydro-1,3-thiazine Hydrochloride

    23. Rometar

    24. 4h-1,3-thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, Monohydrochloride

    25. (5,6-dihydro-4h-[1,3]thiazin-2-yl)-(2,6-dimethyl-phenyl)-amine . Hcl;n-(2,6-dimethylphenyl)-5,6-dihydro-4h-1,3-thiazin-2-amine . Hcl

    26. Xylazine Hydrochloride [usan]

    27. Ccris 8685

    28. Einecs 245-417-0

    29. Unii-ngc3s0882s

    30. Xylazine . Hcl

    31. Xylazine Hydrochloride [usan:usp]

    32. Rompun (tn)

    33. 4h-1,3-thiazine, 5,6-dihydro-2-(2,6-xylidino)-, Monohydrochloride

    34. Schembl38986

    35. Xylazine Hydrochloride (usp)

    36. Chembl1256022

    37. Dtxsid6040248

    38. Xylazine Hydrochloride, >=99%

    39. Hy-b0443a

    40. Chebi:149566

    41. Xylazine Hydrochloride [mi]

    42. Bcp17326

    43. Tox21_501249

    44. 2-(2,6-dimethylphenylamino)-5,6-dihydro-4h-thiazine Hydrochloride

    45. S2516

    46. Akos016003892

    47. Xylazine Hydrochloride [mart.]

    48. Ccg-222553

    49. Lp01249

    50. Xylazine Hydrochloride [usp-rs]

    51. 4h-1,3-thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, Hydrochloride (1:1)

    52. Ncgc00094489-01

    53. Ncgc00261934-01

    54. As-13725

    55. Sy012023

    56. Xylazine Hydrochloride [green Book]

    57. Eu-0101249

    58. Ft-0675880

    59. Sw197048-3

    60. X0059

    61. Xylazine Hydrochloride [usp Monograph]

    62. C74190

    63. D06344

    64. X 1251

    65. A856144

    66. Xylazine Hydrochloride 1000 Microg/ml In Ethanol

    67. J-014976

    68. Sr-01000075296-1

    69. Q27284859

    70. Xylazine Hydrochloride, Vetranal(tm), Analytical Standard

    71. 2-[(2,6-dimethylphenyl)amino]-5,6-dihydro-4h-1,3-thiazine Hydrochloride

    72. Bay1470 Hydrochloride;bay-1470 Hydrochloride;bay 1470 Hydrochloride

    73. N-(2,6-dimethylphenyl)-5,6-dihydro-4h-1,3-thiazin-2-aminehydrochloride

    74. Xyalzine Hcl; Xylazine Hydrochloride Salt; Propofol Impurity; 23076-35-9

    75. Xylazine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    76. Xylazine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    77. 2-[2-(allyloxy)-1,1,2,2-tetrafluoroethoxy]tetrafluoroethanesulfonylfluoride

    78. N-(2,6-dimethylphenyl)-5,6-dihydro-4h-1,3-thiazin-2-amine Hydrochloride (1:1)

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 256.80 g/mol
    Molecular Formula C12H17ClN2S
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count2
    Exact Mass256.0800974 g/mol
    Monoisotopic Mass256.0800974 g/mol
    Topological Polar Surface Area49.7 Ų
    Heavy Atom Count16
    Formal Charge0
    Complexity230
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Analgesics

    Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)

    Muscle Relaxants, Central

    A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358) (See all compounds classified as Muscle Relaxants, Central.)

    Adrenergic alpha-2 Receptor Agonists

    Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Agonists.)

    Hypnotics and Sedatives

    Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)