Please Wait
Applying Filters...
menu
    • menu
    DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

    Virtual Booth

    Contact Supplier

    Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    With Fermion, start the journey of your innovative API.

    Virtual Booth

    Contact Supplier

    Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Menu

    Xylometazoline Hydrochloride

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    GLOBAL SALES INFORMATION

    MARKET PLACE

    REF. STANDARDS & IMPURITIES

    PharmaCompass
    $ API Ref.Price (USD/KG) : 529Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 1218-35-5, Xylometazoline hcl, Xylometazoline (hydrochloride), 2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride, Neo-synephrine ii, Otrivin hydrochloride
    Molecular Formula
    C16H25ClN2
    Molecular Weight
    280.83  g/mol
    InChI Key
    YGWFCQYETHJKNX-UHFFFAOYSA-N
    FDA UNII
    X5S84033NZ
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride
    2.1.2 InChI
    InChI=1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H
    2.1.3 InChI Key
    YGWFCQYETHJKNX-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=CC(=CC(=C1CC2=NCCN2)C)C(C)(C)C.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    X5S84033NZ
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2-(4'-tert-butyl-2',6'-dimethylphenylmethyl)imidazoline

    2. Amidrin

    3. Balkis

    4. Chlorohist-la

    5. Decongest

    6. Espa-rhin

    7. Gelonasal

    8. Idasal

    9. Idril N

    10. Imidin

    11. Nasan

    12. Nasengel Al

    13. Nasengel Ratiopharm

    14. Nasenspray Al

    15. Nasenspray Ratiopharm

    16. Nasentropfen Al

    17. Nasentropfen Ratiopharm

    18. Novorin

    19. Otradrops

    20. Otraspray

    21. Otriven

    22. Otrivin

    23. Otrivin Mentol

    24. Rapako

    25. Schnupfen Endrine

    26. Snup

    27. Stas

    28. Xylometazoline

    29. Xylometazoline Monohydrochloride

    2.3.2 Depositor-Supplied Synonyms

    1. 1218-35-5

    2. Xylometazoline Hcl

    3. Xylometazoline (hydrochloride)

    4. 2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazoline Hydrochloride

    5. Neo-synephrine Ii

    6. Otrivin Hydrochloride

    7. Nsc-757378

    8. Mls000069695

    9. Smr000058526

    10. 2-(4-(tert-butyl)-2,6-dimethylbenzyl)-4,5-dihydro-1h-imidazole Hydrochloride

    11. Dsstox_cid_25223

    12. Dsstox_rid_80760

    13. Dsstox_gsid_45223

    14. 1h-imidazole, 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-, Hydrochloride (1:1)

    15. 2-(4-tert-butyl-2,6-dimethylbenzyl)-4,5-dihydro-1h-imidazole Hydrochloride

    16. X5s84033nz

    17. Xylometazoline Hydrochloride (usp)

    18. 2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazoline Monohydrochloride

    19. 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1h-imidazole;hydrochloride

    20. Sr-01000000230

    21. Ncgc00016101-02

    22. Cas-1218-35-5

    23. Mfcd00238707

    24. Prestwick_574

    25. Opera_id_1744

    26. Neo-synephrine Ii (tn)

    27. Schembl41837

    28. Mls001076518

    29. Spectrum1500614

    30. Chembl1256400

    31. Dtxsid3045223

    32. Regid_for_cid_5282386

    33. Hms1568n07

    34. Hms1921k09

    35. Pharmakon1600-01500614

    36. Xylometazoline Hydrochloride ,(s)

    37. Bcp22148

    38. Hy-b0475

    39. Tox21_110305

    40. Tox21_501269

    41. Ccg-39900

    42. Nsc757378

    43. S2576

    44. Akos015895456

    45. Tox21_110305_1

    46. Ac-8301

    47. Ks-5144

    48. Lp01269

    49. Ncgc00016101-10

    50. Ncgc00094506-01

    51. Ncgc00094506-02

    52. Ncgc00094506-03

    53. Ncgc00094506-04

    54. Ncgc00094506-05

    55. Ncgc00261954-01

    56. Xylometazoline Hydrochloride [mi]

    57. Xylometazoline Hydrochloride [mart.]

    58. Xylometazoline Hydrochloride [vandf]

    59. Eu-0101269

    60. Ft-0603554

    61. Sw196748-3

    62. X0063

    63. Xylometazoline Hydrochloride [usp-rs]

    64. Xylometazoline Hydrochloride [who-dd]

    65. D00757

    66. X 6000

    67. Xylometazoline Hydrochloride, Analytical Standard

    68. 218x355

    69. A804796

    70. Xylometazoline Hydrochloride [ep Monograph]

    71. J-004686

    72. Sr-01000000230-2

    73. Sr-01000000230-7

    74. Xylometazoline Hydrochloride [usp Monograph]

    75. Q27293585

    76. Xylometazoline Hydrochloride, British Pharmacopoeia (bp) Reference Standard

    77. Xylometazoline Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    78. Xylometazoline Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    79. Xylometazoline Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    2.4 Create Date
    2005-10-11
    3 Chemical and Physical Properties
    Molecular Weight 280.83 g/mol
    Molecular Formula C16H25ClN2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count3
    Exact Mass280.1706265 g/mol
    Monoisotopic Mass280.1706265 g/mol
    Topological Polar Surface Area24.4 Ų
    Heavy Atom Count19
    Formal Charge0
    Complexity302
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Nasal Decongestants

    Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993) (See all compounds classified as Nasal Decongestants.)