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ACTIVE PHARMA INGREDIENTS

1 NDC API, 1 VMF, $ API Reference Price

1 NDC API
1 VMF
$ API Reference Price

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1 Canada
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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 2971-90-6, 3,5-dichloro-2,6-dimethylpyridin-4-ol, Meticlorpindol, Coyden, Lerbek, Coccidiostat c

Molecular Formula

C₇H₇Cl₂NO

Molecular Weight

192.04 g/mol

InChI Key

ZDPIZLCVJAAHHR-UHFFFAOYSA-N

FDA UNII

8J763HFF5N

A very effective anticoccidial agent used in poultry.

1 2D Structure

Clopidol

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3,5-dichloro-2,6-dimethyl-1H-pyridin-4-one

2.1.2 InChI

InChI=1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)

2.1.3 InChI Key

ZDPIZLCVJAAHHR-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC1=C(C(=O)C(=C(N1)C)Cl)Cl

2.2 Other Identifiers

2.2.1 UNII

8J763HFF5N

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 3,5-dichloro-2,6-dimethyl-4-pyridinol

2. Clopindol

3. Meticlorpindol

2.3.2 Depositor-Supplied Synonyms

1. 2971-90-6

2. 3,5-dichloro-2,6-dimethylpyridin-4-ol

3. Meticlorpindol

4. Coyden

5. Lerbek

6. Coccidiostat C

7. Metichlorpindol

8. Methylchlorpindol

9. Methylchloropindol

10. 4-pyridinol, 3,5-dichloro-2,6-dimethyl-

11. Clopindol

12. Coyden 25

13. 3,5-dichloro-2,6-dimethyl-4-pyridinol

14. Rigekokcin (rigecoccin)

15. 3,5-dichloro-2,6-dimethyl-1h-pyridin-4-one

16. 2,6-dimethyl-3,5-dichloro-4-pyridinol

17. Nsc 253479

18. 3,5-dichloro-4-hydroxy-2,6-dimethylpyridine

19. Brn 1527826

20. Nsc-253479

21. 8j763hff5n

22. 3,5-dichloro-2,6-dimethylpyridin-4(1h)-one

23. Ncgc00095166-01

24. 3,5-dichloro-2,6-dimethyl-4-hydroxypyridine

25. Clopidol 100 Microg/ml In Acetonitrile/methanol

26. Dsstox_cid_21793

27. Dsstox_rid_79844

28. Dsstox_gsid_41793

29. Clopidolo [dcit]

30. Clopidolum

31. Farmcoccid

32. Pharmcoccid

33. Pharmcoccide

34. Clopidolo

35. Caswell No. 306aa

36. Clopidolum [inn-latin]

37. Clopidol [usan:inn:ban]

38. Cas-2971-90-6

39. Einecs 221-008-2

40. Epa Pesticide Chemical Code 306200

41. Unii-8j763hff5n

42. Hsdb 7907

43. 3,6-dimethylpyridine

44. Clopidol [usan]

45. Clopidol (usan/inn)

46. Clopidol [inn]

47. Clopidol [mi]

48. Spectrum2_000018

49. Spectrum3_001952

50. Clopidol [mart.]

51. 3,6-dimethyl-4-pyridinol

52. Bspbio_003552

53. Clopidol [green Book]

54. Schembl661598

55. Spectrum1505319

56. Spbio_000055

57. Chembl446918

58. Dtxsid8041793

59. Schembl11480048

60. Kbio3_002866

61. Chebi:183853

62. Hms1922d10

63. Hms2090o19

64. Hms2093b15

65. Pharmakon1600-01505319

66. Hy-b1088

67. Zinc8830661

68. Tox21_111465

69. 3,5-dichloro-2,6-dimethylpyridinol

70. Bbl011029

71. Ccg-40048

72. Clopidol 100 Microg/ml In Methanol

73. Mfcd00867211

74. Nsc253479

75. Nsc758964

76. S4142

77. Stk802181

78. Stl032651

79. Akos005622703

80. Akos005642292

81. Tox21_111465_1

82. Cs-4655

83. Ks-1254

84. Nsc-758964

85. 4-pyridinol,5-dichloro-2,6-dimethyl-

86. Clopidol 100 Microg/ml In Acetonitrile

87. Ncgc00095166-02

88. Ncgc00095166-03

89. Ncgc00095166-04

90. Ac-24199

91. Wr-61112

92. 3,5-dichloro-2,6-dimethyl-pyridin-4-ol

93. Sbi-0206752.p001

94. Db-047634

95. Ft-0603199

96. Clopidol, Vetranal(tm), Analytical Standard

97. A16464

98. D03559

99. Ab01563058_01

100. 971c906

101. 971d906

102. A820023

103. Sr-05000002003

104. J-017612

105. Q5135111

106. Sr-05000002003-1

107. Brd-k80036624-001-03-2

2.4 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₇H₇Cl₂NO
Molecular Weight	192.04 g/mol
XLogP3	2.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	190.9904692 g/mol
Monoisotopic Mass	190.9904692 g/mol
Topological Polar Surface Area	29.1 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	252
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Therapeutic Uses

THERAPEUTIC CATEGORY (VETERINARY): Coccidiostat

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 403

Used as an anticoccidiostat in poultry.

American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and BEI's with Other World Wide Occupational Exposure Values. CD-ROM Cincinnati, OH 45240-4148 2010.

Clopidol is mainly coccidiostatic and is active only against the sporozoite stage of Eimeria.

Sams R; Ullmann's Encyclopedia of Industrial Chemistry 7th ed. (2010). NY, NY: John Wiley & Sons; Veterinary Drugs. Online Posting Date: June 15, 2000

MEDICATION (VET): Turkeys grown for meat purposes only: As an aid in the prevention of leucocytozoonosis caused by Leucocytozoon smithi.

US Natl Inst Health; DailyMed. Current Medication Information for COYDEN (clopidol) powder (March 2010). Available from, as of March 8, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=16475&CFID=55487510&CFTOKEN=245e1f8f4d81dce0-5FF4B3EE-CC3A-992F-5E755E9D27611217&jsessionid=ca3047782f012955657f

MEDICATION (VET): Broiler and replacement chickens: As an aid in the prevention of coccidiosis in broilers and replacements for caged layers caused by E. tenella, Eimeria necatrix, Eimeria Acervulina, Eimeria maxima, Eimeria brunetti, Eimeria mivati.

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Coccidiostats

Agents useful in the treatment or prevention of COCCIDIOSIS in man or animals. (See all compounds classified as Coccidiostats.)

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API Reference Price

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