Please Wait
Applying Filters...
menu
    • menu
    Moehs Iberica-PSE
    News
    Moehs & EUROAPI Sign Agreement For Production Of Metamizole In EU

    07 Oct 2024

    // PRESS RELEASE

    Grants From Centro Para El Desarrollo Tecnológico Y La Innovación

    18 Jun 2024

    // PRESS RELEASE

    Moehs Group member of CataloniaBio & HealthTech

    15 May 2024

    // PRESS RELEASE

    Data Compilation
    #PharmaFlow

    Moehs Iberica

    Contact Supplier

    Website

    CPhI WW Frankfurt

    Booth #11.0C6

    Book a meeting

    envelop Contact Supplier

    Latest Content by PharmaCompass

    radio-compass-blog/india-continues-to-top-fda-registered-generics-facilities-sets-up-20-new-units-for-fy24
    Menu

    Moehs Iberica

    EVENTS

    • Webinars & Exhibitions

    PRESENTATION(s)

    VIDEO(s)

    DIGITAL CONTENT

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    Key Products KEY PRODUCTS

    INSPECTIONS & REGISTRATIONS

    PharmaCompass

    Filters

    clear-filterReset all filters
    Left Arrow
    Right Arrow

    Digital content

    Explore the latest content creation from this company

    CORPORATE CONTENT #SupplierSpotlight

    Product List 2023

    read-more

      https://www.pharmacompass.com/pdf/party/content/moehs-iberica-party-content-11386.pdf

      Open PDFOpen PDF
      UploadUpload
      Key ShareShare

    Corporate Presentation

    read-more

      https://www.pharmacompass.com/pdf/party/content/moehs-iberica-party-content-32351.pdf

      Open PDFOpen PDF
      UploadUpload
      Key ShareShare

    GMP Certificate 2024

    read-more

      https://www.pharmacompass.com/pdf/party/content/moehs-iberica-party-content-83409.pdf

      Open PDFOpen PDF
      UploadUpload
      Key ShareShare

    DATA COMPILATION #PharmaFlow

    read-more
    read-more
    Chinese FDA-registered generic facilities gain steam, India maintains lead with 396 facilities

    Chinese FDA-registered generic facilities gain steam, India maintains lead with 396 facilities

    Every year, the US Food and Drug Administration (FDA) publishes the user fee amounts it will collect from manufacturers of pharmaceuticals, generic drugs, biosimilars and medical devices in the coming financial year. The fee for fiscal year 2025 under the Generic Drug User Fee Act (GDUFA) was published on July 31, 2024.The GDUFA, established in 2012, authorizes FDA to assess and collect fees from drug manufacturers to expedite the delivery of safe, high-quality, and affordable generic drugs to the American public.The FDA’s facility payments list under GDUFA reveals that as of November 14, 2024, 1,397 facilities had paid their registration fees for financial year 2025. Of these facilities, 707 or 50.6 percent are active pharmaceutical ingredients (API) facilities, 405 or 29 percent are finished dosage forms (FDF) facilities, 69 (4.9 percent) are facilities that produce both APIs and FDFs, and 216 (15.5 percent) are contract manufacturing services (CMO) sites.Teva Pharmaceuticals, with 29 facility registrations, led the list of companies, followed by Aurobindo Pharma, Sun Pharma, and Dr. Reddy's Laboratories. Fiscal year Facility Registrations 2016 1,425 2017 1,442 2018 1,269 2019 1,286 2020 1,300 2021 1,340 2022 1,385 2023 1,394 2024 1,447 2025 1,397  Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available)India continues to lead with 396 facilities, US and China follow India maintains its dominance in total facility registrations with the FDA, registering 396 facilities for FY2025. This includes 214 API facilities, 135 FDF facilities, 21 facilities engaged in both API and FDF activities, and 26 CMO facilities.The United States holds the second position with 328 facilities, while China strengthened its third position with 197 facilities.With 214 API facilities, India continues to have the largest share of API manufacturing sites, outmatching the combined total of China (128) and the US (83), which together account for 211 facilities. Among European manufacturers, Italy leads with 59 API manufacturing sites, followed by Spain (30) and Germany (25).The US has maintained its lead in FDF facilities with 143 sites, followed closely by India with 135 sites and China with 45 sites. Country API FDF Both CMO Total India 214 135 21 26 396 US 83 143 13 89 328 China 128 45 12 12 197 Italy 59 3 2 19 83 Germany 25 4 1 15 45 Spain 30 9 1 4 44 Canada 7 17   13 37 Taiwan 9 6 5 4 24 Switzerland 15 4   4 23 France 16     6 22 Japan 18   1   19 United Kingdom 12 1   2 15 Mexico 9 1   1 11 Ireland 5 5   1 11   Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) GDUFA III user fee rates increase across categories for FY25The GDUFA, which was reauthorized on September 30, 2022 (as GDUFA III), continues with provisions that will last until September 30, 2027. In July 2024, the FDA published updated user fee rates for FY2025.The facility fees have seen increases across all categories. API facility fees increased by 3 percent for domestic sites (to US$ 41,580) and 2 percent for foreign sites (to US$ 56,580). FDF facility fees rose by 5 percent for both domestic (to US$ 231,952) and foreign sites (to US$ 246,952). CMO facility fees increased by 5 percent for domestic sites (to US$ 55,668) and 4 percent for foreign sites (to US$ 70,668).Additionally, the fee for large-, medium- and small-sized drug applicants has increased by over 9 percent, compared to the 7 percent increase seen in 2023. Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) China leads new facility registrations as FDA records 41 new units in FY25Out of the total 1,397 facilities registered for FY2025, 41 were new registrations (going by Facility FDA Establishment Identifier numbers). China led the way with 13 new facilities, followed closely by India with 11 new facilities, while the US secured the third position with eight new facilities.The new registrations included 15 API facilities, 13 CMO facilities, 12 FDF facilities, and one facility engaged in both API and FDF activities. Chinese companies dominated the new FDF registrations with six facilities: Chengdu Shuode Pharma, Chengdu Suncadia Medicine, Cipla (Jiangsu), GE Healthcare (Shanghai), Luoxin Aurovitas Pharma (Chengdu), and Zhejiang Xianju Pharma.India added two new FDF facilities through Eugia Steriles and Zydus Pharma. Malaysia registered two FDF facilities through Novugen Pharma and Novugen Oncology, while Turkey’s Insud Pharma subsidiary Exeltis and US’ RK Pharma registered one FDF facility each.The 13 new CMO facilities included, Acme Generics, Emcure, Esjay Pharma, Fordoz Pharma, Fourrts Laboratories, Laboratoires KABS, PharmaMax, Quality Packaging Specialists International, Ritsa Pharma, Shanghai Aucyun Pharma, Sichuan Huiyu Pharma, Taejoon Pharm, and Tubilux Pharma.In the API category, the 15 new registrations included Acharya Chemicals, Hainan Poly Pharma, CBL Patras, EUROAPI, Hybio Pharma, Medilux Laboratories, Metrochem API, Purolite, Chengdu Easton Biopharma, Sionc Pharma, Smithfield Bioscience, Xttrium Laboratories, Zhejiang Hengkang Pharma, Moehs Iberica and Shilpa Pharma. Armstrong Pharmaceuticals registered the sole facility for both APIs and FDFs.So far, 92 facilities have not renewed their registration. Among these was a facility owned by Sandoz subsidiary Eon Labs in Wilson, North Carolina (US), which is permanently closed. In fact, the geographical distribution of non-renewals shows that 30 facilities were from the US, while India and China accounted for 14 and nine non-renewals respectively. Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) Our viewThe FY 2025 GDUFA facility registration data indicates a continued strong presence of Indian manufacturers in the US generic drug market, particularly in API production. However, China's leadership in new facility registrations, especially in FDF manufacturing, suggests that the global generic drug supply chain landscape may evolve considerably in the coming years. 
    subscribeSubscribe
    ExcelExcel Download

    Impressions: 11520

    https://www.pharmacompass.com/radio-compass-blog/chinese-fda-registered-generic-facilities-gain-steam-india-maintains-lead-with-396-facilities

    #PharmaFlow by PHARMACOMPASS
    21 Nov 2024
    Share Share
    DMF filings hit all-time high in Q3 2024; China tops list with 58% increase in Type II submissions

    DMF filings hit all-time high in Q3 2024; China tops list with 58% increase in Type II submissions

    Drug Master Files, or DMFs, are confidential documents that play a crucial role in the pharmaceutical industry. These files, submitted to the US Food and Drug Administration (FDA), contain detailed information about ingredients, manufacturing processes, and packaging of medicines. They help the FDA oversee drug quality. Of the four types, Type II DMFs involve active pharmaceutical ingredients (APIs) for both branded and generic drugs. The third quarter (Q3) of 2024 saw Type II DMF submissions set a new record. A total of 309 Type II DMFs were submitted to the FDA during this period, a substantial 24.6 percent increase over Q3 2023 (with 248 submissions). The second quarter of 2024 too saw a remarkable increase, with 237 Type II DMFs being submitted compared to 178 in Q2 2023. View FDA DMF Filings in Q3 2024 (Power BI Dashboard, Free Excel Available) China witnesses steep rise in DMF submissions, beats India with maximum filings In Q3 2024, China filed 153 DMFs submissions, marking a substantial 57.7 percent increase from the 97 submissions filed in Q3 2023. India maintained its strong position but fell to the number two spot with 110 DMFs, representing a modest 3.8 percent increase from 106 in Q3 2023. The US, which came a distant third, saw a slight decline in DMF submissions, with 13 filed in Q3 2024, as compared to 18 in Q3 2023. For several years, India had a lead in Type II DMFs. Since 2020, which marked the start of the pandemic, we have noticed a gradual increase in DMFs filed by China. This year, China has surpassed India considerably in the first three quarters. During the first nine months of 2024, China submitted 372, while India filed 286 DMFs. If this lead is maintained in Q4, DMFs from China will surpass that of India in 2024.  Amongst European countries, Spain led with seven DMFs, followed by Italy at four, and Germany and the Netherlands at three each. Among other nations, Japan contributed six while Israel submitted four DMFs. In company-wise tally, China’s Jiangsu East-Mab Biomedical Technology topped the list with an impressive 14 DMFs. On its heels were Indian companies — MSN at 13 DMFs, and Vamsi Labs and Hetero Drugs at nine DMFs each. China’s Porton Pharma and Wuxi AppTec filed five, while Shanghai Keze Yongxin Biotechnology, and Qingdao Glycogene Pharmaceutical contributed four submissions each. India's Maithri Drugs also submitted four. Japanese company Santeja filed five. Overall, Asia accounted for nearly 90 percent, with China contributing a dominant 49.5 percent of all DMF submissions. India was at 35.6 percent, the US at 4.2 percent, while Europe contributed 6.5 percent.  View FDA DMF Filings in Q3 2024 (Power BI Dashboard, Free Excel Available) Diabetes, obesity, cancer, women’s health drugs emerge as hot molecules in Q3 2024 In terms of molecules, semaglutide (used for the treatment of type 2 diabetes and weight management) and relugolix (to treat prostate cancer and uterine fibroids) saw six DMF filings each in Q3 2024, indicating significant industry interest in these compounds. Following closely behind were semaglutide’s competitor tirzepatide and overactive bladder therapy vibegron, garnering four DMFs each. Finerenone (a non-steroidal drug for chronic kidney disease associated with type 2 diabetes) and voclosporin (an immunosuppressant for lupus nephritis) saw three DMFs each.  The last quarter also witnessed the introduction of 14 molecules with first-time DMFs. Among them were acetoxy empagliflozin, cabozantinib fumarate, tivozanib hydrochloride monohydrate, diosmetin, trilaciclib, clenbuterol hydrochloride, fenoterol hydrobromide, tapinarof and fezolinetant. Fezolinetant, with a DMF from Spain’s Moehs Iberica, is the active ingredient in Astellas’ Veozah, which is the first non-hormonal treatment for menopausal symptoms approved by the FDA. Tapinarof, filed by India’s Maithri Drugs, is used in Vtama, a novel steroid-free psoriasis cream. Other compounds that made their DMF debut include berotralstat, calcium phosphoryl choline chloride, phloroglucinol dihydrate, belumosudil mesylate and trimethylphloroglucinol. During Q2 2024, there were 19 drugs that saw DMF submissions for the first time, including molecules like triptorelin, sorafenib, pralsetinib, trilaciclib dihydrochloride, resmetirom (hepatology) and teneligliptin hydrochloride hydrate (metabolic disorders).  View FDA DMF Filings in Q3 2024 (Power BI Dashboard, Free Excel Available)    GDUFA fee for FY 2025: The FDA’s Generic Drug User Fee Amendments (GDUFA) is a law designed to speed access to safe and effective generic drugs to the public and reduce costs to the industry. The fiscal year 2025 fee rates were published on July 31, 2024. The FDA has revised fees under GDUFA III for all categories. While there is a slight increase in the DMF fee from US$ 94,682 in 2024 to US$ 95,084 in 2025, the ANDA fee has witnessed a significant jump — from US$ 252,453 in 2024 to US$ 321,920 in 2025. FY 2024 and FY 2025 User Fee Rates Generic drug fee category Fees rates for FY 2024 Fees rates for FY 2025 Applications: Abbreviated New Drug Application (ANDA) US$ 2,52,453   US$ 3,21,920   Drug Master File (DMF) US$ 94,682 US$ 95,084 Facilities: Active Pharmaceutical Ingredient (API)—Domestic US$ 40,464 US$ 41,580 API—Foreign US$ 55,464 US$ 56,580 Finished Dosage Form (FDF)—Domestic US$ 2,20,427   US$ 2,31,952 FDF—Foreign US$ 2,35,427   US$ 2,46,952 Contract Manufacturing Organization (CMO)—Domestic US$ 52,902 US$ 55,668 CMO—Foreign US$ 67,902 US$ 70,668 GDUFA Program: Large size operation generic drug applicant US$ 17,29,629   US$ 18,91,664 Medium size operation generic drug applicant US$ 6,91,852   US$ 7,56,666 Small business generic drug applicant US$ 1,72,963   US$ 1,89,166 Our view The highlight of the last few quarters has been the sharp rise in Type II DMF filings from China. The submission of a DMF is not required by law or any FDA regulation. FDA’s DMF guideline offers guidance on acceptable approaches to meeting regulatory requirements. Moreover, DMFs establish trust in APIs from lesser-known companies. With a growing emphasis on compliance and quality assurance, it appears that Chinese drug companies are eager to demonstrate their commitment to high standards and build trust in the US market. And that’s good news for the pharmaceutical industry.   
    subscribeSubscribe
    ExcelExcel Download

    Impressions: 6498

    https://www.pharmacompass.com/radio-compass-blog/dmf-filings-hit-all-time-high-in-q3-2024-china-tops-list-with-58-increase-in-type-ii-submissions

    #PharmaFlow by PHARMACOMPASS
    24 Oct 2024
    Share Share

    NEWS #PharmaBuzz

    read-more
    read-more
    Moehs & EUROAPI Sign Agreement For Production Of Metamizole In EU
    Moehs & EUROAPI Sign Agreement For Production Of Metamizole In EU

    07 Oct 2024

    // PRESS RELEASE

    https://moehs.com/moehs-group-and-euroapi-sign-an-exclusive-agreement-for-the-production-of-metamizole-in-europe/

    PRESS RELEASE
    07 Oct 2024
    Share Share
    Grants From Centro Para El Desarrollo Tecnológico Y La Innovación
    Grants From Centro Para El Desarrollo Tecnológico Y La Innovación

    18 Jun 2024

    // PRESS RELEASE

    https://moehs.com/2grants-from-centro-para-el-desarrollo-tecnologico-y-la-innovacion/

    PRESS RELEASE
    18 Jun 2024
    Share Share
    Moehs Group member of CataloniaBio & HealthTech
    Moehs Group member of CataloniaBio & HealthTech

    15 May 2024

    // PRESS RELEASE

    https://moehs.com/member-of-cataloniabio-and-healthtech/

    PRESS RELEASE
    15 May 2024
    Share Share
    Carbon Footprint Certificate 2023
    Carbon Footprint Certificate 2023

    25 Apr 2024

    // PRESS RELEASE

    https://moehs.com/carbon-footprint-certificate-2023/

    PRESS RELEASE
    25 Apr 2024
    Share Share
    Participation In S3 Industry Project
    Participation In S3 Industry Project

    04 Apr 2024

    // PRESS RELEASE

    https://moehs.com/participation-in-s3-industry-project/

    PRESS RELEASE
    04 Apr 2024
    Share Share
    Project Nitroso-Sitagliptin Impurity
    Project Nitroso-Sitagliptin Impurity

    07 Mar 2024

    // PRESS RELEASE

    https://moehs.com/project-nitroso-sitagliptin-impurity/

    PRESS RELEASE
    07 Mar 2024
    Share Share
    Contact Moehs Iberica and get a quotation

    Moehs Iberica is a supplier offers 88 products (APIs, Excipients or Intermediates).

    Find a price of Amlodipine Besylate bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Articaine Hydrochloride bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Bisoprolol Fumarate bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Carvedilol bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Celiprolol Hydrochloride bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Duloxetine Hydrochloride bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Lansoprazole bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Lidocaine bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Lidocaine Hydrochloride bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Mepivacaine Hydrochloride bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Metoprolol Tartrate bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Nifedipine bulk with DMF, CEP, JDMF offered by Moehs Iberica

    Find a price of Acebutolol Hydrochloride bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Acetylcysteine bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Amantadine Hydrochloride bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Amlodipine Besylate bulk with CEP, JDMF offered by Moehs Iberica

    Find a price of Bupivacaine Hydrochloride bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Carbocisteine bulk with CEP, JDMF offered by Moehs Iberica

    Find a price of Fenofibrate bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Metoprolol Succinate bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Pantoprazole Sodium bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Quetiapine Hemifumarate bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Rabeprazole bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Sotalol Hydrochloride bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Triamterene bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Trimebutine Maleate bulk with CEP, JDMF offered by Moehs Iberica

    Find a price of Venlafaxine Hydrochloride bulk with DMF, CEP offered by Moehs Iberica

    Find a price of Abrocitinib bulk with DMF offered by Moehs Iberica

    Find a price of Amlodipine Besylate bulk with JDMF offered by Moehs Iberica

    Find a price of Carbocisteine bulk with JDMF offered by Moehs Iberica

    Find a price of Celiprolol Hydrochloride bulk with JDMF offered by Moehs Iberica

    Find a price of Choline Fenofibrate bulk with DMF offered by Moehs Iberica

    Find a price of Dexmedetomidine Hydrochloride bulk with DMF offered by Moehs Iberica

    Find a price of Elagolix Sodium bulk with DMF offered by Moehs Iberica

    Find a price of Fenofibrate bulk with DMF offered by Moehs Iberica

    Find a price of Fezolinetant bulk with DMF offered by Moehs Iberica

    Find a price of Lasmiditan bulk with DMF offered by Moehs Iberica

    Find a price of Lemborexant bulk with DMF offered by Moehs Iberica

    Find a price of Mavacamten bulk with DMF offered by Moehs Iberica

    Find a price of Obeticholic Acid bulk with DMF offered by Moehs Iberica

    Find a price of Prilocaine bulk with DMF offered by Moehs Iberica

    Find a price of Prilocaine Hydrochloride bulk with DMF offered by Moehs Iberica

    Find a price of Relugolix bulk with DMF offered by Moehs Iberica

    Find a price of Remimazolam Besylate bulk with DMF offered by Moehs Iberica

    Find a price of Rimegepant Sulfate bulk with DMF offered by Moehs Iberica

    Find a price of Rivaroxaban bulk with CEP offered by Moehs Iberica

    Find a price of Ropivacaine Hydrochloride bulk with DMF offered by Moehs Iberica

    Find a price of Sertraline Hydrochloride bulk with CEP offered by Moehs Iberica

    Find a price of Sitagliptin Phosphate bulk with DMF offered by Moehs Iberica

    Find a price of Sumatriptan bulk with DMF offered by Moehs Iberica

    Find a price of Tirbanibulin bulk with DMF offered by Moehs Iberica

    Find a price of Vericiguat bulk with DMF offered by Moehs Iberica

    Find a price of Amantadine Sulphate bulk offered by Moehs Iberica

    Find a price of Blarcamesine bulk offered by Moehs Iberica

    Find a price of Butalbital bulk offered by Moehs Iberica

    Find a price of Carbocysteine Lysine bulk offered by Moehs Iberica

    Find a price of Chloral Hydrate bulk offered by Moehs Iberica

    Find a price of Daridorexant bulk offered by Moehs Iberica

    Find a price of Deucravacitinib bulk offered by Moehs Iberica

    Find a price of Domiphen Bromide bulk offered by Moehs Iberica

    Find a price of Doxazosin Mesylate bulk offered by Moehs Iberica

    Find a price of Edoxaban Tosylate bulk offered by Moehs Iberica

    Find a price of Empagliflozin bulk offered by Moehs Iberica

    Find a price of Levobupivacaine bulk offered by Moehs Iberica

    Find a price of Levocloperastine Fendizoate bulk offered by Moehs Iberica

    Find a price of Linzagolix bulk offered by Moehs Iberica

    Find a price of Linzagolix Choline bulk offered by Moehs Iberica

    Find a price of Magnesium Lactate Dihydrate bulk offered by Moehs Iberica

    Find a price of Mebeverine bulk offered by Moehs Iberica

    Find a price of Methenamine Hippurate bulk offered by Moehs Iberica

    Find a price of Nifuroxazide bulk offered by Moehs Iberica

    Find a price of Nikethamide bulk offered by Moehs Iberica

    Find a price of Norepinephrine Bitartrate bulk offered by Moehs Iberica

    Find a price of Pentobarbital Sodium bulk offered by Moehs Iberica

    Find a price of Phenobarbital bulk offered by Moehs Iberica

    Find a price of Phenobarbital Sodium bulk offered by Moehs Iberica

    Find a price of Phentermine Hydrochloride bulk offered by Moehs Iberica

    Find a price of Picloxydine Dihydrochloride bulk offered by Moehs Iberica

    Find a price of Propylthiouracil bulk offered by Moehs Iberica

    Find a price of Pyrantel Pamoate bulk offered by Moehs Iberica

    Find a price of SECOBARBITAL SODIUM bulk offered by Moehs Iberica

    Find a price of Sitagliptin Hydrochloride bulk offered by Moehs Iberica

    Find a price of Sotagliflozin bulk offered by Moehs Iberica

    Find a price of Tamoxifen Citrate bulk offered by Moehs Iberica

    Find a price of Thiopental Sodium bulk offered by Moehs Iberica

    Find a price of Vildagliptin bulk offered by Moehs Iberica

    Find a price of Xylometazoline Hydrochloride bulk offered by Moehs Iberica

    Find a price of Zavegepant HCl bulk offered by Moehs Iberica