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Florfenicol

Suanfarma Florfenicol

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Fishfa Biogenics: Renowned Manufacturer, & Exporter of Tacrolimus & Mupirocin API.

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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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Transo-Pharm GmbH works globally to supply Active Pharmaceutical Ingredients adhering to the highest quality & GMP standards.

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12 API Suppliers, 1 EU WC, 3 NDC API, 11 VMF, 11 Listed Suppliers, $ API Reference Price

12 API Suppliers
1 EU WC
3 NDC API
11 VMF
11 Listed Suppliers
$ API Reference Price

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9 Canada
10 Listed Dossiers

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12 APIs

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Suanfarma Florfenicol

Synopsis

ACTIVE PHARMA INGREDIENTS

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3

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11

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11

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API REF. PRICE (USD/KG)

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$ 203

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19

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Europe

9

Canada

0

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10

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Chemistry

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Also known as: 73231-34-2, Nuflor, (-)-florfenicol, Sch-25298, 76639-94-6, Sch 25298

Molecular Formula

C₁₂H₁₄Cl₂FNO₄S

Molecular Weight

358.2 g/mol

InChI Key

AYIRNRDRBQJXIF-NXEZZACHSA-N

FDA UNII

9J97307Y1H

Florfenicol

Florfenicol is a fluorinated synthetic analog of thiamphenicol.

1 2D Structure

Florfenicol

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

2.1.2 InChI

InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

2.1.3 InChI Key

AYIRNRDRBQJXIF-NXEZZACHSA-N

2.1.4 Canonical SMILES

CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)NC(=O)C(Cl)Cl)O

2.1.5 Isomeric SMILES

CS(=O)(=O)C1=CC=C(C=C1)[C@H]([C@@H](CF)NC(=O)C(Cl)Cl)O

2.2 Other Identifiers

2.2.1 UNII

9J97307Y1H

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 3-fluorothiamphenicol

2. Chloramphen

3. Florphenicol

4. Sch 25298

5. Sch-25298

6. Thiamphenicol, 3-fluoro

2.3.2 Depositor-Supplied Synonyms

1. 73231-34-2

2. Nuflor

3. (-)-florfenicol

4. Sch-25298

5. 76639-94-6

6. Sch 25298

7. Nuflor Gold

8. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

9. Chebi:87185

10. D-threo-2,2-dichloro-n-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

11. 9j97307y1h

12. Nsc-759287

13. Acetamide, 2,2-dichloro-n-((1s,2r)-1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-

14. Aquafen

15. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)acetamide

16. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide

17. Dsstox_cid_25500

18. Dsstox_rid_80918

19. Dsstox_gsid_45500

20. Acetamide, 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-, (r-(r*,s*))-

21. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl]acetamide

22. D-(-)-threo-2-dichloroacetamido-3-fluoro-1-(4-methylsulfonylphenyl)-1-propanol

23. Florfenicol [usan:inn:ban]

24. 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide

25. Unii-9j97307y1h

26. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl)acetamide

27. Ncgc00016922-01

28. Cas-73231-34-2

29. Mfcd00864834

30. Nuflor (tn)

31. Florfenicol [mi]

32. Prestwick0_000955

33. Prestwick1_000955

34. Prestwick2_000955

35. Prestwick3_000955

36. Florfenicol [inn]

37. Florfenicol [jan]

38. Florfenicol (usan/inn)

39. Florfenicol [usan]

40. Florfenicol [mart.]

41. Schembl49425

42. Bspbio_000950

43. Mls002154071

44. Spbio_003099

45. Bpbio1_001046

46. Chembl1241590

47. Dtxsid9045500

48. Florfenicol [green Book]

49. Schembl21835523

50. (-)-florfenicol;sch-25298

51. Hms1570p12

52. Hms2090i10

53. Hms2097p12

54. Hms2230k18

55. Hms3714p12

56. Zinc537733

57. Act06682

58. Hy-b1374

59. Osurnia Component Florfenicol

60. Zeleris Component Florfenicol

61. Tox21_110683

62. S4201

63. Akos015889457

64. Tox21_110683_1

65. Ac-4340

66. Ccg-220955

67. Cs-4857

68. Db11413

69. Florfenicol Component Of Osurnia

70. Florfenicol Component Of Zeleris

71. Ks-5028

72. Nsc 759287

73. 2,2-dichloro-n-[(1s,2r)-1-(fluoromethyl)-2-hydroxy-2-(4-methylsulfonylphenyl)ethyl]acetamide

74. Florfenicol [ema Epar Veterinary]

75. Ncgc00179366-01

76. Ncgc00179366-03

77. Ncgc00179366-04

78. 2,2-dichloro-n-((alphas,betar)-alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

79. Benzenesulfonic Acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-, Methyl Ester, (r-(r*,s*))-

80. Bf166386

81. Smr001233384

82. (methylsulfonyl)phenyl)propan-2-yl)acetamide

83. Ab00513976

84. F0811

85. Sw197224-3

86. D04194

87. T72886

88. Ab00513976_09

89. 231f342

90. A838774

91. Q408400

92. Florfenicol, Analytical Standard, For Drug Analysis

93. Brd-k11298197-001-03-9

94. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-

95. (1r,2s)-2-dichloroacetamido-3-fluoro-1-[4-(methylsulfonyl) Phenyl]-1-propanol

96. (1r,2s)-2-dichloroacetamido-3-fluoro-1-[4-(methylsulfonyl)phenyl]-1-propanol

97. 2,2-dichlor-n-((1r,2s)-3-fluor-1-hydroxy- 1-(4-(methylsulfonyl)-phenyl)-propan-2-yl)-ethanamide

98. 2,2-dichloro-n-((.alpha.s,.beta.r)-.alpha.-(fluoromethyl)-.beta.-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

99. 2,2-dichloro-n-[(1r,2r)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

100. 2,2-dichloro-n-{(1r,2s)-3-fluoro-1-hydroxy-1-[4-(methanesulfonyl)phenyl]propan-2-yl}acetamide

101. D-threo-2,2-dichloro-n-(.alpha.-(fluoromethyl)-.beta.-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₄Cl₂FNO₄S
Molecular Weight	358.2 g/mol
XLogP3	0.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	357.0004627 g/mol
Monoisotopic Mass	357.0004627 g/mol
Topological Polar Surface Area	91.8 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	447
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

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API Reference Price

[{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637865000,"product":"FLORFENICOL","address":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB","city":"HYDERABAD,TELANGANA","supplier":"ZHEJIANG HISOAR PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"TAIZHOU","customer":"CRONUS PHARMA SPECIALITIES ","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"280","totalValueFC":"2823.6","currency":"USD","unitRateINR":"21028","date":"26-Nov-2021","totalValueINR":"210280","totalValueInUsd":"2823.6","indian_port":"GMR HYDERABAD AVIATION-SEZ","hs_no":"29414000","bill_no":"1005594","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"TAIZHOU","supplierAddress":"N\/A","customerAddress":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1659033000,"product":"FLORFENICOL (FOR R & D PURPOSE)","address":"5TH FLOOR ENKAY CENTRE A BLOCK,,VA NIJYA NIKUNJ UDYOG VIHAR PHASE V","city":"GURGAON,HARYANA","supplier":"SHANDONG GUOBANG PHARMACEUTICAL ","supplierCountry":"CHINA","foreign_port":"NA","customer":"FELIX GENERICS PRIVATE ","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"325","totalValueFC":"1654.3","currency":"USD","unitRateINR":"26308.8","date":"29-Jul-2022","totalValueINR":"131543.75","totalValueInUsd":"1654.3","indian_port":"DELHI AIR","hs_no":"29329990","bill_no":"9775165","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"5TH FLOOR ENKAY CENTRE A BLOCK,,VA NIJYA NIKUNJ UDYOG VIHAR PHASE V"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1665685800,"product":"FLORFENICOL","address":"PLOT NO-51,MEENAKSHI 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WEST,MAHARASHTRA","supplier":"ZHEJIANG HISOAR CHUANNAN PHARMACEUTICAL CO., LTD.","supplierCountry":"CHINA","foreign_port":"NA","customer":"ALIVIRA ANIMAL HEALTH","customerCountry":"INDIA","quantity":"9.87","actualQuantity":"9.87","unit":"KGS","unitRateFc":"250","totalValueFC":"2472.5","currency":"USD","unitRateINR":"20612.5","date":"20-Oct-2022","totalValueINR":"203445.38","totalValueInUsd":"2472.5","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"2960705","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"3RD FLOOR NO 301 DOSTI PINNACLE,PL OT NO E-7 ROAD NO 22 WAGLE ESTATE"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1671129000,"product":"FLORFENICOL","address":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB","city":"HYDERABAD,TELANGANA","supplier":"ZHEJIANG HISOAR PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"PUDONG\/SHANGHAI","customer":"CRONUS PHARMA SPECIALITIES ","customerCountry":"INDIA","quantity":"147.00","actualQuantity":"147","unit":"KGS","unitRateFc":"230.3","totalValueFC":"34328.2","currency":"USD","unitRateINR":"19244","date":"16-Dec-2022","totalValueINR":"2828861","totalValueInUsd":"34328.2","indian_port":"GMR HYDERABAD AVIATION-SEZ","hs_no":"29414000","bill_no":"1005932","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"PUDONG\/SHANGHAI","supplierAddress":"N\/A","customerAddress":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1683138600,"product":"FLORFENICOL TL NO TL AZ 23 000704 FOR R D PURPOSE NOT FORSALE","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR HIGHWAY SATELLITE CROSS ROADS,","city":"AHMEDABAD","supplier":"ZHEJIANG HISOAR PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"HANGCHOW HANGZHOU","customer":"ZYDUS LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"24.10","actualQuantity":"24.1","unit":"KGS","unitRateFc":"110","totalValueFC":"2678.9","currency":"USD","unitRateINR":"9146.5","date":"04-May-2023","totalValueINR":"220430.65","totalValueInUsd":"2678.9","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"China","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW HANGZHOU","supplierAddress":"","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR HIGHWAY SATELLITE CROSS ROADS,"}]

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