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Chemistry

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Also known as: Ivermectin, Dihydroavermectin b1a, 70288-86-7, 22,23-dihydroavermectin b1a, 70161-11-4, Ivermectin component b1a
Molecular Formula
C48H74O14
Molecular Weight
875.1  g/mol
InChI Key
AZSNMRSAGSSBNP-XPNPUAGNSA-N
FDA UNII
91Y2202OUW

Ivermectin
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
1 2D Structure

Ivermectin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
2.1.2 InChI
InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
2.1.3 InChI Key
AZSNMRSAGSSBNP-XPNPUAGNSA-N
2.1.4 Canonical SMILES
CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C
2.1.5 Isomeric SMILES
CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C
2.2 Other Identifiers
2.2.1 UNII
91Y2202OUW
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Eqvalan

2. Ivermectin

3. Ivomec

4. Mectizan

5. Mk 933

6. Mk-933

7. Mk933

8. Stromectol

2.3.2 Depositor-Supplied Synonyms

1. Ivermectin

2. Dihydroavermectin B1a

3. 70288-86-7

4. 22,23-dihydroavermectin B1a

5. 70161-11-4

6. Ivermectin Component B1a

7. 71827-03-7

8. Avermectin H2b1a

9. 5-o-demethyl-22,23-dihydroavermectin A1a

10. Chebi:63941

11. 91y2202ouw

12. (2ae,4e,5's,6s,6'r,7s,8e,11r,13r,15s,17ar,20r,20ar,20bs)-6'-[(2s)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2h,7h-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-l-arabino-hexopyranosyl)-3-o-methyl-alpha-l-arabino-hexopyranoside

13. Mk-933

14. (1r,4s,5's,6r,6'r,8r,10e,12s,13s,14e,16e,20r,21r,24s)-6'-[(2s)-butan-2-yl]-21,24-dihydroxy-12-[(2r,4s,5s,6s)-5-[(2s,4s,5s,6s)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one

15. Ivermectin B1a-d2

16. C48h74o14

17. Unii-91y2202ouw

18. 22,23-dihydroavermectin B(1)a

19. Ncgc00163233-01

20. Ivermectin (ivm)

21. Ivm

22. Einecs 276-046-2

23. Dihydro Avermectin Bla

24. Brn 4643153

25. 22,23-dihydro-5-o-demethylavermectin A1a

26. H2b1a

27. Prestwick3_000156

28. Dsstox_cid_3181

29. Ivermectin (mk-0933)

30. Dsstox_rid_76909

31. Dsstox_gsid_23181

32. Bspbio_000292

33. Schembl312795

34. Bpbio1_000322

35. Chembl263291

36. Dtxsid8023181

37. Chebi:94551

38. Hms2089m09

39. Hms2095o14

40. Hms3712o14

41. Wca82703

42. Tox21_112034

43. Bdbm50409816

44. Mfcd30496678

45. S1351

46. Akos027470116

47. Ivermectin Component B1a [mi]

48. Zinc238808778

49. Zinc252286706

50. Ac-6014

51. Ccg-220156

52. Ncgc00186639-01

53. Ncgc00186639-03

54. As-14167

55. Bi166167

56. Cas-71827-03-7

57. Hy-126937

58. Ab00513813

59. Cs-0108408

60. 22,23-dihydroavermectin B1a; Ivermectin

61. Ab00513813-02

62. Ab00513813-03

63. Ab00513813_04

64. Avermectin A1a, 22,23-dihydro-5-o-demethyl-

65. 288i867

66. Ivermectin, Antibiotic For Culture Media Use Only

67. Q-201262

68. Brd-k24652731-001-02-7

69. Brd-k85554912-001-08-9

70. Q27132923

71. Ivermectin, British Pharmacopoeia (bp) Reference Standard

72. Ivermectin, European Pharmacopoeia (ep) Reference Standard

73. Ivermectin, United States Pharmacopeia (usp) Reference Standard

74. Ivermectin, Pharmaceutical Secondary Standard; Certified Reference Material

75. (2ae,4e,5's,6s,6'r,7s,8e,11r,13r,15s,17ar,20r,20ar,20bs)-6'-[(2s)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17

76. Clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-l-arabino-hexopyranosyl)-3-o-methyl-alpha-l-arabino-hexopyranoside

2.4 Create Date
2005-11-20
3 Chemical and Physical Properties
Molecular Weight 875.1 g/mol
Molecular Formula C48H74O14
XLogP34.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count14
Rotatable Bond Count8
Exact Mass874.50785703 g/mol
Monoisotopic Mass874.50785703 g/mol
Topological Polar Surface Area170 Ų
Heavy Atom Count62
Formal Charge0
Complexity1680
Isotope Atom Count0
Defined Atom Stereocenter Count20
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count3
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Treatment of rosacea


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Antiparasitic Agents

Drugs used to treat or prevent parasitic infections. (See all compounds classified as Antiparasitic Agents.)


Insecticides

Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics. (See all compounds classified as Insecticides.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Pediculicide [EPC]; Antiparasitic [EPC]
5.3 ATC Code

D - Dermatologicals

D11 - Other dermatological preparations

D11A - Other dermatological preparations

D11AX - Other dermatologicals

D11AX22 - Ivermectin


P - Antiparasitic products, insecticides and repellents

P02 - Anthelmintics

P02C - Antinematodal agents

P02CF - Avermectines

P02CF01 - Ivermectin


API SUPPLIERS

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01

Centrient Pharmaceuticals

Netherlands

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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LGM Pharma

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
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Virtual BoothLGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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LGM Pharma CB

03

Suanfarma

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSuanfarma, at the Core of a Better Life.

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04

DKSH

Switzerland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

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05

Jai Radhe Sales

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothJai Radhe Sales is your partner for all your sourcing needs.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Jai Radhe Sales

06

Atman Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothAtman Pharmaceuticals: A One Stop Solution Provider to All Your API Needs.

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Atman Pharmaceuticals

07

Zhejiang Hisun Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Zhejiang Hisun Pharmaceutical

China

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08

Industriale Chimica

Italy

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Industriale Chimica

Italy

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09

Hovione

Portugal

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Hovione

Portugal

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10

Delta Synthetic Co. Ltd

Taiwan

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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Delta Synthetic Co. Ltd

Taiwan

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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USDMF

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01

Delta Tech Ltd

Taiwan

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01

Pharma Manufacturing 2024
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GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 17673

Submission : 2004-07-18

Status : Inactive

Type : II

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02

Hovione Pharmascience Ltd

Portugal

USDMF

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Pharma Manufacturing 2024
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GDUFA

DMF Review : Complete

Rev. Date : 2013-01-09

Pay. Date : 2012-12-14

DMF Number : 21395

Submission : 2008-03-05

Status : Active

Type : II

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03

Pharma Manufacturing 2024
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03

Pharma Manufacturing 2024
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GDUFA

DMF Review : Complete

Rev. Date : 2022-04-06

Pay. Date : 2022-01-13

DMF Number : 36494

Submission : 2021-11-15

Status : Active

Type : II

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04

Pharma Manufacturing 2024
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04

Pharma Manufacturing 2024
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GDUFA

DMF Review : Complete

Rev. Date : 2014-02-08

Pay. Date : 2012-12-18

DMF Number : 21624

Submission : 2008-05-08

Status : Active

Type : II

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05

Hebei Meihe Pharmaceutical Co Ltd

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USDMF

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05

Hebei Meihe Pharmaceutical Co Ltd

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GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 38553

Submission : 2023-06-27

Status : Active

Type : II

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Shanghai Tongren Pharmaceutical Co L...

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Shanghai Tongren Pharmaceutical Co L...

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Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 13037

Submission : 1998-06-15

Status : Inactive

Type : II

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Haimen Pharmaceutical Factory

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USDMF

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Haimen Pharmaceutical Factory

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GDUFA

DMF Review : N/A

Rev. Date :

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DMF Number : 12755

Submission : 1997-11-21

Status : Inactive

Type : II

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API Reference Price

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LIMITED","customerCountry":"INDIA","quantity":"3.06","actualQuantity":"3.06","unit":"KGS","unitRateFc":"100","totalValueFC":"309.1","currency":"USD","unitRateINR":"8445","date":"15-Jul-2024","totalValueINR":"25841.7","totalValueInUsd":"309.1","indian_port":"JNPT","hs_no":"29419090","bill_no":"4519422","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15\/F, HODO INTERNATIONAL PLAZA,531 ZHONGSHAN ROAD,WUXI 214002 CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720981800,"product":"IVERMECTIN EP","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"CIDIC CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"4.16","actualQuantity":"4.16","unit":"KGS","unitRateFc":"100","totalValueFC":"420.3","currency":"USD","unitRateINR":"8445","date":"15-Jul-2024","totalValueINR":"35131.2","totalValueInUsd":"420.3","indian_port":"JNPT","hs_no":"29419090","bill_no":"4519422","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15\/F, HODO INTERNATIONAL PLAZA,531 ZHONGSHAN ROAD,WUXI 214002 CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720981800,"product":"IVERMECTIN EP","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"CIDIC CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"5.10","actualQuantity":"5.1","unit":"KGS","unitRateFc":"100","totalValueFC":"515.2","currency":"USD","unitRateINR":"8445","date":"15-Jul-2024","totalValueINR":"43069.5","totalValueInUsd":"515.2","indian_port":"JNPT","hs_no":"29419090","bill_no":"4519422","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15\/F, HODO INTERNATIONAL PLAZA,531 ZHONGSHAN ROAD,WUXI 214002 CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720981800,"product":"IVERMECTIN EP","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"CIDIC CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"10.50","actualQuantity":"10.5","unit":"KGS","unitRateFc":"100","totalValueFC":"1060.8","currency":"USD","unitRateINR":"8445","date":"15-Jul-2024","totalValueINR":"88672.5","totalValueInUsd":"1060.8","indian_port":"JNPT","hs_no":"29419090","bill_no":"4519422","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15\/F, HODO INTERNATIONAL PLAZA,531 ZHONGSHAN ROAD,WUXI 214002 CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720981800,"product":"IVERMECTIN EP","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"CIDIC CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"10.50","actualQuantity":"10.5","unit":"KGS","unitRateFc":"97.5","totalValueFC":"1034.3","currency":"USD","unitRateINR":"8233.9","date":"15-Jul-2024","totalValueINR":"86455.69","totalValueInUsd":"1034.3","indian_port":"JNPT","hs_no":"29419090","bill_no":"4519422","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15\/F, HODO INTERNATIONAL PLAZA,531 ZHONGSHAN ROAD,WUXI 214002 CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720981800,"product":"IVERMECTIN EP","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"CIDIC CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"21.00","actualQuantity":"21","unit":"KGS","unitRateFc":"100","totalValueFC":"2121.6","currency":"USD","unitRateINR":"8445","date":"15-Jul-2024","totalValueINR":"177345","totalValueInUsd":"2121.6","indian_port":"JNPT","hs_no":"29419090","bill_no":"4519422","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15\/F, HODO INTERNATIONAL PLAZA,531 ZHONGSHAN ROAD,WUXI 214002 CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720981800,"product":"IVERMECTIN EP","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"CIDIC CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"26.25","actualQuantity":"26.25","unit":"KGS","unitRateFc":"97.5","totalValueFC":"2585.7","currency":"USD","unitRateINR":"8233.9","date":"15-Jul-2024","totalValueINR":"216139.22","totalValueInUsd":"2585.7","indian_port":"JNPT","hs_no":"29419090","bill_no":"4519422","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15\/F, HODO INTERNATIONAL PLAZA,531 ZHONGSHAN ROAD,WUXI 214002 CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720981800,"product":"IVERMECTIN EP","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"CIDIC CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"81.60","actualQuantity":"81.6","unit":"KGS","unitRateFc":"100","totalValueFC":"8243.8","currency":"USD","unitRateINR":"8445","date":"15-Jul-2024","totalValueINR":"689112","totalValueInUsd":"8243.8","indian_port":"JNPT","hs_no":"29419090","bill_no":"4519422","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15\/F, HODO INTERNATIONAL PLAZA,531 ZHONGSHAN ROAD,WUXI 214002 CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721845800,"product":"IVERMECTIN VET IP","address":"601, 6TH FLR, MORYA LAND MARK,","city":"MALL ANDHERI [W], MUMBAI","supplier":"HEBEI MEIHE PHARMACEUTICAL CO.LTD.","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"EASTERN CHEMICALS MUMBAI ","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"99","totalValueFC":"50623.2","currency":"USD","unitRateINR":"8463.3","date":"25-Jul-2024","totalValueINR":"4231646","totalValueInUsd":"50623.2","indian_port":"JNPT","hs_no":"29339990","bill_no":"4685293","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO.8, XINGYUAN ROAD, BIOLOGICAL INDUSTRY PARK, NANBAISHE TOWN, ZHAO COUNTY, HEBEI PROVINCE CHINA China","customerAddress":"601, 6TH FLR, MORYA LAND MARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726770600,"product":"IVERMECTIN","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"HEBEI VEYONG PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"26.20","actualQuantity":"26.2","unit":"KGS","unitRateFc":"100.5","totalValueFC":"2662.7","currency":"USD","unitRateINR":"8516.5","date":"20-Sep-2024","totalValueINR":"223133.52","totalValueInUsd":"2662.7","indian_port":"JNPT","hs_no":"29419090","bill_no":"5709522","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO. 68 GANJIANG ROAD, SHIJIAZHUANG HEBEI CHINA 052165 SDNF CN","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726857000,"product":"IVERMECTIN VET IP","address":"ROOM NO.34\/B, MANGALDAS BLDG NO.1","city":"MARINE LINES, MUMBAI, M.S.","supplier":"APELOA PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"MINERVA BIOGENIX PRIVATE LIMITED","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"95","totalValueFC":"96190.3","currency":"USD","unitRateINR":"8060.9","date":"21-Sep-2024","totalValueINR":"8060860.77","totalValueInUsd":"96190.3","indian_port":"JNPT","hs_no":"29419090","bill_no":"5716986","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"FLAT \/RM 2914 29 F HO KING COMMERCIAL CENTRE,2-16 FA YUEN STREET MONGKONG KL CN","customerAddress":"ROOM NO.34\/B, MANGALDAS BLDG NO.1"}]
01-Jan-2021
26-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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FDA Orange Book

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01

TARO

U.S.A
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : IVERMECTIN

Dosage Form : LOTION;TOPICAL

Dosage Strength : 0.5%

Approval Date : 2020-05-06

Application Number : 210720

RX/OTC/DISCN : OTC

RLD : No

TE Code :

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02

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : SKLICE

Dosage Form : LOTION;TOPICAL

Dosage Strength : 0.5%

Approval Date : 2012-02-07

Application Number : 202736

RX/OTC/DISCN : OTC

RLD : Yes

TE Code :

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03

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : IVERMECTIN

Dosage Form : TABLET;ORAL

Dosage Strength : 3MG

Approval Date : 2014-10-24

Application Number : 204154

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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04

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : SOOLANTRA

Dosage Form : CREAM;TOPICAL

Dosage Strength : 1%

Approval Date : 2014-12-19

Application Number : 206255

RX/OTC/DISCN : RX

RLD : Yes

TE Code : AB

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05

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : STROMECTOL

Dosage Form : TABLET;ORAL

Dosage Strength : 6MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

Approval Date : 1996-11-22

Application Number : 50742

RX/OTC/DISCN : DISCN

RLD : Yes

TE Code :

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06

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : STROMECTOL

Dosage Form : TABLET;ORAL

Dosage Strength : 3MG

Approval Date : 1998-10-08

Application Number : 50742

RX/OTC/DISCN : RX

RLD : Yes

TE Code : AB

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07

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : IVERMECTIN

Dosage Form : CREAM;TOPICAL

Dosage Strength : 1%

Approval Date : 2020-04-13

Application Number : 210225

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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08

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : IVERMECTIN

Dosage Form : TABLET;ORAL

Dosage Strength : 3MG

Approval Date :

Application Number : 218324

RX/OTC/DISCN :

RLD :

TE Code :

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09

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : IVERMECTIN

Dosage Form : CREAM;TOPICAL

Dosage Strength : 1%

Approval Date : 2019-09-13

Application Number : 210019

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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10

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

IVERMECTIN

Brand Name : IVERMECTIN

Dosage Form : LOTION;TOPICAL

Dosage Strength : 0.5%

Approval Date : 2022-03-21

Application Number : 212485

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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Europe

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01

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Scatol

Dosage Form : Tablet

Dosage Strength : mg

Packaging : Blisterpakning 4item

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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02

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Scatol

Dosage Form : Tablet

Dosage Strength : mg

Packaging : Blisterpakning 12item

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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03

Galderma Nordic AB,

Switzerland
Pharmtech & Ingredients
Not Confirmed
arrow

Galderma Nordic AB,

Switzerland
arrow
Pharmtech & Ingredients
Not Confirmed

ivermectin

Brand Name : Soolantra

Dosage Form : CREAM

Dosage Strength : 10 MG / G

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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04

Galderma Nordic AB

Switzerland
Pharmtech & Ingredients
Not Confirmed
arrow

Galderma Nordic AB

Switzerland
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Soolantra

Dosage Form : Cream

Dosage Strength : 10 mg/g

Packaging : Tube of plastic

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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05

Galderma SA

Switzerland
Pharmtech & Ingredients
Not Confirmed
arrow

Galderma SA

Switzerland
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Soolantra

Dosage Form : Cream

Dosage Strength : 10mg/g

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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06

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Ivermectin Medical Valley

Dosage Form : Tablet

Dosage Strength : mg

Packaging : Blisterpakning 4item

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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07

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Ivermectin Medical Valley

Dosage Form : Tablet

Dosage Strength : mg

Packaging : Blisterpakning 10item

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

blank

08

Orifarm AS

Denmark
Pharmtech & Ingredients
Not Confirmed
arrow

Orifarm AS

Denmark
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Ivermectin Orifarm

Dosage Form : Tablet

Dosage Strength : mg

Packaging : Blisterpakning 4item

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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09

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Ivermectin STADA

Dosage Form : Tablet

Dosage Strength : mg

Packaging : Blisterpakning 4item

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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Listed Dossiers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Ivermectin

Brand Name :

Dosage Form : Injection

Dosage Strength : 1%

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info :

Ivermectin

Dosage : Injection

Dosage Strength : 1%

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Supriya

02

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name :

Dosage Form : Granules

Dosage Strength : 12MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

02

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Dosage : Granules

Dosage Strength : 12MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

03

Grupo Chemo

Costa Rica
Pharmtech & Ingredients
Not Confirmed
arrow

Grupo Chemo

Costa Rica
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : ivermectin CHEMO®

Dosage Form : TABLET

Dosage Strength : 6MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generics

Registration Country : Costa Rica

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03

Grupo Chemo

Costa Rica
Pharmtech & Ingredients
Not Confirmed
arrow

Grupo Chemo

Costa Rica
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Dosage : TABLET

Dosage Strength : 6MG

Brand Name : ivermectin CHEMO®

Approval Date :

Application Number :

Registration Country : Costa Rica

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04

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name :

Dosage Form : Tablet

Dosage Strength : 12MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

04

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Dosage : Tablet

Dosage Strength : 12MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

05

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name :

Dosage Form : Tablet

Dosage Strength : 6MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

05

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Dosage : Tablet

Dosage Strength : 6MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

06

Hiral Labs

India
Pharmtech & Ingredients
Not Confirmed
arrow

Hiral Labs

India
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name :

Dosage Form : Uncoated Tablet

Dosage Strength : 6mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

06

Hiral Labs

India
Pharmtech & Ingredients
Not Confirmed
arrow

Hiral Labs

India
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Dosage : Uncoated Tablet

Dosage Strength : 6mg

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

07

Hiral Labs

India
Pharmtech & Ingredients
Not Confirmed
arrow

Hiral Labs

India
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name :

Dosage Form : Uncoated Tablet

Dosage Strength : 12mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

07

Hiral Labs

India
Pharmtech & Ingredients
Not Confirmed
arrow

Hiral Labs

India
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Dosage : Uncoated Tablet

Dosage Strength : 12mg

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

08

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Canimect

Dosage Form : Oral Solution

Dosage Strength : 0.1%

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

08

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Dosage : Oral Solution

Dosage Strength : 0.1%

Brand Name : Canimect

Approval Date :

Application Number :

Registration Country : India

blank

09

Pharmtech & Ingredients
Not Confirmed
arrow
arrow
Pharmtech & Ingredients
Not Confirmed

Ivermectin

Brand Name : Evermec LA

Dosage Form : Liquid Injection

Dosage Strength : 3.15%

Packaging : 100ML,500ML

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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Ivermectin

Dosage : Liquid Injection

Dosage Strength : 3.15%

Brand Name : Evermec LA

Approval Date :

Application Number :

Registration Country : China

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Ivermectin; Clorsulon

Brand Name : Evermec-110 Plus

Dosage Form : Liquid Injection

Dosage Strength : 1%; 10%

Packaging : 50ML,100ML,250ML,500ML

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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10

Pharmtech & Ingredients
Not Confirmed
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Pharmtech & Ingredients
Not Confirmed

Ivermectin; Clorsulon

Dosage : Liquid Injection

Dosage Strength : 1%; 10%

Brand Name : Evermec-110 Plus

Approval Date :

Application Number :

Registration Country : China

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - LOTION;TOPICAL - 0.5%

USFDA APPLICATION NUMBER - 202736

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DOSAGE - CREAM;TOPICAL - 1%

USFDA APPLICATION NUMBER - 206255

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