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    Chemistry

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    Also known as: Xanax, 28981-97-7, Trankimazin, Niravam, Tafil, Tranquinal
    Molecular Formula
    C17H13ClN4
    Molecular Weight
    308.8  g/mol
    InChI Key
    VREFGVBLTWBCJP-UHFFFAOYSA-N
    FDA UNII
    YU55MQ3IZY
    Alprazolam
    A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
    Alprazolam is a Benzodiazepine.
    1 2D Structure

    Alprazolam

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
    2.1.2 InChI
    InChI=1S/C17H13ClN4/c1-11-20-21-16-10-19-17(12-5-3-2-4-6-12)14-9-13(18)7-8-15(14)22(11)16/h2-9H,10H2,1H3
    2.1.3 InChI Key
    VREFGVBLTWBCJP-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4
    2.2 Other Identifiers
    2.2.1 UNII
    YU55MQ3IZY
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Alprazolan

    2. Alprox

    3. Apo Alpraz

    4. Apo-alpraz

    5. Cassadan

    6. D-65mt

    7. D65mt

    8. Esparon

    9. Kalma

    10. Novo Alprazol

    11. Novo-alprazol

    12. Nu Alpraz

    13. Nu-alpraz

    14. Ralozam

    15. Tafil

    16. Trankimazin

    17. U-31,889

    18. U31,889

    19. Xanax

    2.3.2 Depositor-Supplied Synonyms

    1. Xanax

    2. 28981-97-7

    3. Trankimazin

    4. Niravam

    5. Tafil

    6. Tranquinal

    7. Alplax

    8. Constan

    9. Frontal

    10. Solanax

    11. Xanor

    12. Apo-alpraz

    13. 8-chloro-1-methyl-6-phenyl-4h-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

    14. Xanax Xr

    15. Alcelam

    16. Anpress

    17. Relaxol

    18. Tricalma

    19. Valeans

    20. Xanagis

    21. Zolarem

    22. Alpaz

    23. Alpram

    24. Alzam

    25. Panix

    26. Prinox

    27. Zoldac

    28. Zotran

    29. Alprazolam Intensol

    30. Tus-1

    31. Xanolam

    32. Zolam

    33. Zopax

    34. Zopic

    35. Tafil D

    36. Xanax Ts

    37. D 65mt

    38. Alprazolam Civ

    39. 8-chloro-1-methyl-6-phenyl-4h-s-triazolo(4,3-a)(1,4)benzodiazepine

    40. U-31,889

    41. Cassadan

    42. Esparon

    43. Neurol

    44. U 31889

    45. U-31889

    46. Alpronax

    47. Alzolam

    48. Bestrol

    49. Ralozam

    50. Alprox

    51. Restyl

    52. Yu55mq3izy

    53. Chembl661

    54. Nsc-760140

    55. Novo-alprazol

    56. 8-chloro-1-methyl-6-phenyl-4h-s-triazolo[4,3-a][1,4]benzodiazepine

    57. Nu-alpraz

    58. Chebi:2611

    59. Alprazolamum

    60. Pharnax

    61. Prazolan

    62. Tensivan

    63. Zacetin

    64. Zanapam

    65. Alprax

    66. Ksalol

    67. Mialin

    68. Prazam

    69. Unilan

    70. Zoldax

    71. Algad

    72. Alzon

    73. Helex

    74. Zaxan

    75. Zenax

    76. Gen-alprazolan

    77. 4h-s-triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-1-methyl-6-phenyl-

    78. 4h-(1,2,4)triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-1-methyl-6-phenyl-

    79. 4h-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, 8-chloro-1-methyl-6-phenyl-

    80. Ncgc00159466-02

    81. Alprazolamum [inn-latin]

    82. U 31,889

    83. Tus 1

    84. Panistat

    85. Alprazolam Extended Release Tablets

    86. Staccato-alprazolam

    87. Smr000149316

    88. Xanax (tn)

    89. Hsdb 7207

    90. Einecs 249-349-2

    91. Unii-yu55mq3izy

    92. Az-002

    93. Tgar01p

    94. Brn 1223125

    95. Dea No. 2882

    96. 08h

    97. Alprazolam [usan:usp:inn:ban:jan]

    98. Ap-1002

    99. 3u5j

    100. Alprazolam [mi]

    101. Alprazolam [inn]

    102. Alprazolam [jan]

    103. Alprazolam [hsdb]

    104. Alprazolam [usan]

    105. Dsstox_cid_2577

    106. Alprazolam [vandf]

    107. Alprazolam [mart.]

    108. Schembl8398

    109. Alprazolam [who-dd]

    110. Dsstox_rid_76639

    111. Bidd:pxr0150

    112. Dsstox_gsid_22577

    113. Zinc903

    114. Mls000559000

    115. Mls000759485

    116. Mls001423979

    117. Bidd:gt0475

    118. Alprazolam (jp17/usp/inn)

    119. Gtpl7111

    120. Alprazolam [ep Impurity]

    121. Alprazolam [orange Book]

    122. Dtxsid4022577

    123. Alprazolam [ep Monograph]

    124. Alprazolam [usp Monograph]

    125. Hms2051a10

    126. Hms3393a10

    127. Pharmakon1600-01502395

    128. Alprazolam 0.1 Mg/ml In Methanol

    129. Alprazolam 1.0 Mg/ml In Methanol

    130. Bcp28608

    131. Tox21_111692

    132. Bbl028160

    133. Bdbm50001728

    134. Nsc760140

    135. Stk590494

    136. Akos005066050

    137. Ccg-100855

    138. Db00404

    139. Nc00105

    140. Nsc 760140

    141. 4h-(1,2,4)triazolo(4,3-alpha)(1,4)benzodiazepine, 8-chloro-1-methyl-6-phenyl-

    142. Ncgc00159466-03

    143. 51339-48-1

    144. Ac-18721

    145. Cas-28981-97-7

    146. C06817

    147. D00225

    148. 981a977

    149. A819702

    150. Q319877

    151. W-107015

    152. Brd-k32398298-001-01-4

    153. Alprazolam, European Pharmacopoeia (ep) Reference Standard

    154. 8-chloro-1-methyl-6-phenyl-4h-s-triazolo [4,3-a] [1,4] Benzodiazepine

    155. 8-chloro-1-methyl-6-phenyl-4h-s-triazolo [4,3-a][1,4] Benzodiazepine

    156. 8-chloro-6-phenyl-1-methyl-4h-s-triazolo-[4,3-a][1,4]benzodiazepine

    157. (z)-8-chloro-1-methyl-6-phenyl-4h-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine

    158. 4h-(1,2,4)triazolo(4,3-.alpha.)(1,4)benzodiazepine, 8-chloro-1-methyl-6-phenyl-

    159. 8-chloranyl-1-methyl-6-phenyl-4h-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

    160. 8-chloro-1-methyl-6-phenyl-4h-s-triazolo(4,3-.alpha.)(1,4)benzodiazepine

    161. Alprazolam Solution, 1 Mg/ml In Methanol, Analytical Standard, For Drug Analysis

    162. Alprazolam Solution, 1.0 Mg/ml In Methanol, Ampule Of 1 Ml, Certified Reference Material

    163. 12-chloro-3-methyl-9-phenyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene

    164. 1246182-61-5

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 308.8 g/mol
    Molecular Formula C17H13ClN4
    XLogP32.1
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count1
    Exact Mass308.0828741 g/mol
    Monoisotopic Mass308.0828741 g/mol
    Topological Polar Surface Area43.1 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity434
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 10  
    Drug NameAlprazolam
    PubMed HealthAlprazolam (By mouth)
    Drug ClassesAntianxiety
    Drug LabelAlprazolamextended-release tabletscontain alprazolam USP, which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-] [...
    Active IngredientAlprazolam
    Dosage FormTablet, extended release; Tablet, orally disintegrating; Tablet; Concentrate
    RouteOral
    Strength1mg/ml; 0.5mg; 2mg; 1mg; 0.25mg; 3mg
    Market StatusPrescription
    CompanyCorepharma; Vintage Pharms; Anchen Pharms; Mylan Pharms; Amneal Pharms Ny; Actavis Elizabeth; Ani Pharms; Aurobindo Pharma Usa; Actavis Labs Fl; Apotex; Vintage; Dava Intl; Zydus Pharms Usa; Sandoz; Sun Pharma Global; Par Pharm; Mylan; Impax Labs; Roxane

    2 of 10  
    Drug NameAzor
    PubMed HealthAmlodipine/Olmesartan (By mouth)
    Drug ClassesAntihypertensive
    Active Ingredientolmesartan medoxomil; Amlodipine besylate
    Dosage FormTablet
    RouteOral
    Strengtheq 5mg base; eq 10mg base; 40mg; 20mg
    Market StatusPrescription
    CompanyDaiichi Sankyo

    3 of 10  
    Drug NameNiravam
    PubMed HealthAlprazolam (By mouth)
    Drug ClassesAntianxiety
    Drug LabelNIRAVAM (alprazolam orally disintegrating tablets) contains alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds. NIRAVAM is an orally administered formulation of alprazolam which rapidl...
    Active IngredientAlprazolam
    Dosage FormTablet, orally disintegrating
    RouteOral
    Strength0.5mg; 1mg; 0.25mg; 2mg
    Market StatusPrescription
    CompanyUcb

    4 of 10  
    Drug NameXanax
    PubMed HealthAlprazolam (By mouth)
    Drug ClassesAntianxiety
    Drug LabelXANAX XR Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-] [1,4] benzodiazepine. The m...
    Active IngredientAlprazolam
    Dosage FormTablet
    RouteOral
    Strength0.5mg; 1mg; 0.25mg; 2mg
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    5 of 10  
    Drug NameXanax xr
    Drug LabelXANAX XR Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-] [1,4] benzodiazepine. The m...
    Active IngredientAlprazolam
    Dosage FormTablet, extended release
    RouteOral
    Strength0.5mg; 1mg; 2mg; 3mg
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    6 of 10  
    Drug NameAlprazolam
    PubMed HealthAlprazolam (By mouth)
    Drug ClassesAntianxiety
    Drug LabelAlprazolamextended-release tabletscontain alprazolam USP, which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-] [...
    Active IngredientAlprazolam
    Dosage FormTablet, extended release; Tablet, orally disintegrating; Tablet; Concentrate
    RouteOral
    Strength1mg/ml; 0.5mg; 2mg; 1mg; 0.25mg; 3mg
    Market StatusPrescription
    CompanyCorepharma; Vintage Pharms; Anchen Pharms; Mylan Pharms; Amneal Pharms Ny; Actavis Elizabeth; Ani Pharms; Aurobindo Pharma Usa; Actavis Labs Fl; Apotex; Vintage; Dava Intl; Zydus Pharms Usa; Sandoz; Sun Pharma Global; Par Pharm; Mylan; Impax Labs; Roxane

    7 of 10  
    Drug NameAzor
    PubMed HealthAmlodipine/Olmesartan (By mouth)
    Drug ClassesAntihypertensive
    Active Ingredientolmesartan medoxomil; Amlodipine besylate
    Dosage FormTablet
    RouteOral
    Strengtheq 5mg base; eq 10mg base; 40mg; 20mg
    Market StatusPrescription
    CompanyDaiichi Sankyo

    8 of 10  
    Drug NameNiravam
    PubMed HealthAlprazolam (By mouth)
    Drug ClassesAntianxiety
    Drug LabelNIRAVAM (alprazolam orally disintegrating tablets) contains alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds. NIRAVAM is an orally administered formulation of alprazolam which rapidl...
    Active IngredientAlprazolam
    Dosage FormTablet, orally disintegrating
    RouteOral
    Strength0.5mg; 1mg; 0.25mg; 2mg
    Market StatusPrescription
    CompanyUcb

    9 of 10  
    Drug NameXanax
    PubMed HealthAlprazolam (By mouth)
    Drug ClassesAntianxiety
    Drug LabelXANAX XR Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-] [1,4] benzodiazepine. The m...
    Active IngredientAlprazolam
    Dosage FormTablet
    RouteOral
    Strength0.5mg; 1mg; 0.25mg; 2mg
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    10 of 10  
    Drug NameXanax xr
    Drug LabelXANAX XR Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-] [1,4] benzodiazepine. The m...
    Active IngredientAlprazolam
    Dosage FormTablet, extended release
    RouteOral
    Strength0.5mg; 1mg; 2mg; 3mg
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    4.2 Therapeutic Uses

    Anti-Anxiety Agents; GABA Modulators; Hypnotics and Sedatives

    National Library of Medicine's Medical Subject Headings. Alprazolam. Online file (MeSH, 2016). Available from, as of October 28, 2016: https://www.nlm.nih.gov/mesh/2016/mesh_browser/MBrowser.html

    Xanax Tablets (alprazolam) are indicated for the management of anxiety disorder (a condition corresponding most closely to the APA Diagnostic and Statistical Manual (DSM-IIIR) diagnosis of generalized anxiety disorder) or the short-term relief of symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. /Included in US product labeling/

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    Xanax is also indicated for the treatment of panic disorder, with or without agoraphobia. /Included in US product labeling/

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    VET: /Alprazolam/ may be useful in cats to treat anxiety disorders and unlike oral diazepam in cats, has not been implicated in causing liver failure.

    Plumb D.C. Veterinary Drug Handbook. 8th ed. (pocket). Ames, IA: Wiley-Blackwell, 2015., p. 45

    VET: Alprazolam may be useful for adjunctive therapy in anxious, aggressive dogs or in those demonstrating panic reactions. It is mose effective when used in advance of a triggering event. (NOTE: Some clinicians believe that benzodiazepines are contraindicated in aggressive dogs as anxiety may actually restrain the animal from aggressive tendencies.)

    Plumb D.C. Veterinary Drug Handbook. 8th ed. (pocket). Ames, IA: Wiley-Blackwell, 2015., p. 45

    4.3 Drug Warning

    Episodes of mania and hypomania have been reported in depressed patients receiving alprazolam.

    McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 2381

    Pregnancy risk category: D /POSITIVE EVIDENCE OF RISK. Studies in humans, or investigational or post-marketing data, have demonstrated fetal risk. Nevertheless, potential benefits from the use of the drug may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective./

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    Benzodiazepines can potentially cause fetal harm when administered to pregnant women. If Xanax is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus. Because of experience with other members of the benzodiazepine class, Xanax is assumed to be capable of causing an increased risk of congenital abnormalities when administered to a pregnant woman during the first trimester. Because use of these drugs is rarely a matter of urgency, their use during the first trimester should almost always be avoided. The possibility that a woman of childbearing potential may be pregnant at the time of institution of therapy should be considered. Patients should be advised that if they become pregnant during therapy or intend to become pregnant they should communicate with their physicians about the desirability of discontinuing the drug.

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    Safety and efficacy of alprazolam have not been established in children younger than 18 years of age.

    McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 2381

    For more Drug Warnings (Complete) data for ALPRAZOLAM (16 total), please visit the HSDB record page.

    4.4 Drug Indication

    Alprazolam is indicated for the acute treatment of generalized anxiety disorder in adults. Alprazolam is also indicated, either as a standard or extended-release formulation, for the treatment of panic disorder with or without agoraphobia in adults. Alprazolam may also be prescribed off-label for insomnia, premenstrual syndrome, and depression.

    FDA Label

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Alprazolam is a benzodiazepine that binds -aminobutyric acid (GABA) type-A receptors (GABAARs) to enhance their inhibitory effect on neurotransmission, specifically in the brain. Concomitant use with opioids may result in profound sedation, respiratory depression, coma, and death; patients taking benzodiazepines and opioids concurrently may require lower doses of one or both medications, depending on their clinical situation. Patients with pre-existing impaired respiratory function are at increased risk of adverse effects including death during treatment with benzodiazepines. In addition, due to its CNS depressant effects, patients taking alprazolam should avoid operating heavy machinery or driving and should avoid other CNS depressants such as alcohol. As with other benzodiazepines, alprazolam carries a risk of abuse, misuse, and addiction, which is higher in predisposed individuals and may require strict monitoring. Cessation of therapy may result in acute or protracted withdrawal symptoms, which may be life-threatening; the patient dose should be gradually tapered whenever discontinuation or reduced dosage are necessary. Newborns born to mothers using alprazolam later in pregnancy may suffer from sedation and withdrawal symptoms. As CYP3A is required for the initial step in alprazolam metabolism, alprazolam is contraindicated in patients taking strong CYP3A inhibitors, such as ketoconazole and itraconazole; milder CYP3A inhibitors still necessitate alprazolam dosage adjustments. Lastly, benzodiazepines may have negative effects, such as panic disorders, increased suicide incidence, and episodes of mania/hypomania, in patients suffering from depression.

    5.2 MeSH Pharmacological Classification

    GABA Modulators

    Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here. (See all compounds classified as GABA Modulators.)

    Hypnotics and Sedatives

    Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)

    Anti-Anxiety Agents

    Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)

    5.3 FDA Pharmacological Classification
    5.3.1 Active Moiety
    ALPRAZOLAM
    5.3.2 FDA UNII
    YU55MQ3IZY
    5.3.3 Pharmacological Classes
    Benzodiazepines [CS]; Benzodiazepine [EPC]
    5.4 ATC Code

    N05BA12

    S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

    N - Nervous system

    N05 - Psycholeptics

    N05B - Anxiolytics

    N05BA - Benzodiazepine derivatives

    N05BA12 - Alprazolam

    5.5 Absorption, Distribution and Excretion

    Absorption

    Alprazolam administered orally is rapidly absorbed in the gastrointestinal tract, reaching Cmax in about 1.8 (1-2) hours. Absorption is high, resulting in an oral bioavailability of 84-91%. A 1 mg oral dose results in a Cmax of 12-22 g/L. The extended-release formulation of alprazolam (XANAX XR) has similar absorption, bioavailability, and pharmacokinetics as the standard release, with the exception that the Tmax is ~10 hours compared to 1-2 hours. Temporal dosing alters these parameters, with Cmax increasing by 30% and Tmax decreasing by one hour when dosed at night as opposed to in the morning. Food has an effect on alprazolam absorption; a high-fat meal up to two hours before dosing increases the Cmax by ~25% and either a reduction (food consumed immediately prior to dosing) or increase (food consumed after dosing) of ~1/3 in Tmax. Neither the AUC nor half-life are appreciably affected by eating.

    Route of Elimination

    Alprazolam is mainly eliminated in the urine. A large portion of the dose is eliminated as unmetabolized alprazolam. <10% of the dose is eliminated as alpha-hydroxy-alprazolam and 4-hydroxy-alprazolam.

    Volume of Distribution

    Alprazolam has a volume of distribution following oral administration of 0.8-1.3L/kg. Alprazolam crosses the blood-brain barrier.

    Clearance

    A 0.8 mg oral dose of alprazolam had a clearance of 0.90 0.21 mL/min/kg, which increased to 2.13 0.54 mL/min/kg when coadministered with the strong CYP3A4 inducer carbamazepine. Other studies have demonstrated a clearance of 0.70-1.5mL/min/kg.

    In vitro, alprazolam is bound (80 percent) to human serum protein. Serum albumin accounts for the majority of the binding.

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    Alprazolam and its metabolites are excreted primarily in the urine.

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    Following oral administration, alprazolam is readily absorbed. Peak concentrations in the plasma occur in 1 to 2 hours following administration. Plasma levels are proportionate to the dose given; over the dose range of 0.5 to 3.0 mg, peak levels of 8.0 to 37 ng/mL were observed.

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    The newborn of a mother reporting alprazolam use during pregnancy presented with respiratory distress and clinical features consistent with neonatal withdrawal syndrome or neonatal sepsis of vertical transmission. Alprazolam and its main metabolite (alpha-hydroxyalprazolam) were detected in cord serum, neonatal urine and also in neonatal hair, meconium and placenta, accounting for both acute and chronic exposure to this benzodiazepine during intrauterine life. ...

    PMID:17453885 Garcia-Algar O et al; Clin Toxicol (Phila) 45 (3): 295-8 (2007)

    5.6 Metabolism/Metabolites

    Alprazolam is metabolized to less effective metabolites by various CYPs including CYP3A4, CYP3A5, CYP3A7, and CYP2C9. The majority of alprazolam metabolism is mediated by hydroxylation via CYP3As. 4-hydroxyalprazolam has 20% the binding affinity of the parent drug, alpha-hydroxyalprazolam has 66% the affinity, and the benzophenone metabolite has <1% the affinity.

    Alprazolam, an anti-anxiety agent, is metabolized in rat and human liver by P4503A1 and P4503A4 respectively, to 4-hydroxy alprazolam (4-OHALP, pharmacologically less active) and alpha-hydroxy alprazolam (alpha-OHALP, pharmacologically more active). We examined P450 mediated metabolism of alprazolam by rat and human brain microsomes and observed that the relative amount of alpha-OHALP formed in brain was higher than liver. This biotransformation was mediated by a P450 isoform belonging to P4503A subfamily, which is constitutively expressed in neuronal cells in rat and human brain. The formation of larger amounts of alpha-OHALP in neurons points to local modulation of pharmacological activity in brain, at the site of action of the anti-anxiety drug. Since hydroxy metabolites of alprazolam are hydrophilic and not easily cleared through blood-CSF barrier, alpha-OHALP would potentially have a longer half-life in brain.

    PMID:12196913 Pai HV et al; Pharmacogenomics J 2 (4): 243-58 (2002)

    Alprazolam is extensively metabolized in humans, primarily by cytochrome P450 3A4 (CYP3A4), to two major metabolites in the plasma: 4-hydroxyalprazolam and a-hydroxyalprazolam. A benzophenone derived from alprazolam is also found in humans. Their half-lives appear to be similar to that of alprazolam. The plasma concentrations of 4-hydroxyalprazolam and a-hydroxyalprazolam relative to unchanged alprazolam concentration were always less than 4%. The reported relative potencies in benzodiazepine receptor binding experiments and in animal models of induced seizure inhibition are 0.20 and 0.66, respectively, for 4-hydroxyalprazolam and a-hydroxyalprazolam. Such low concentrations and the lesser potencies of 4-hydroxyalprazolam and a-hydroxyalprazolam suggest that they are unlikely to contribute much to the pharmacological effects of alprazolam. The benzophenone metabolite is essentially inactive.

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    Alprazolam has known human metabolites that include 4-Hydroxyalprazolam and Beta-Hydroxyalprazolam.

    S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560

    5.7 Biological Half-Life

    Alprazolam has a mean plasma elimination half-life of 11.2 hours in healthy patients (range 6.3-26.9 hours). The mean half-life is 16.3 hours (range 9.0-26.9 hours) in the elderly, 21.8 hours (range 9.9-40.4 hours) in obese patients, and 19.7 hours (range 5.8-65.3 hours) in patients with alcoholic liver disease. The half-life is 25% higher in Asian patients compared to Caucasians. Other studies have shown the half-life to be 9-16h. The extended-release formulation has a half-life of 10.7-15.8 hours in healthy adult patients.

    Using a specific assay methodology, the mean plasma elimination half-life of alprazolam has been found to be about 11.2 hours (range: 6.3-26.9 hours) in healthy adults.

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    5.8 Mechanism of Action

    Neurotransmission relies on excitatory and inhibitory signalling. -aminobutyric acid (GABA) type-A receptors (GABAARs) are members of the pentameric ligand-gated ion channel (PLGIC) superfamily located synaptically and perisynaptically to mediate phasic inhibition and extrasynaptically to mediate tonic inhibition. GABAARs comprise a variety of subunits from a homologous family whose members are named based on sequence identity as one of 1-6, 1-3, 1-3, , , , , and 1-3. Each subunit possesses an extracellular (ECD), transmembrane (TMD), and intracellular (ICD) domain; inter-subunit interfaces are the primary points of neurotransmitter and modulator binding, described by coordination of the principal (+) and complementary (-) sites in each subunit. Binding of GABA to GABAARs induces pore opening, rapid flow of chloride ions, and synaptic hyperpolarization, which in turn manifests as an inhibitory signal. The most prevalent GABAARs _in vivo_ are the 122 receptors, which contain both GABA (+/-) and benzodiazepine (BZD, +/-) binding sites in the intersubunit interfaces of the relevant subunits. In general, any receptors containing an x/z interface, where x = 1-3,5 and z = 1-3, have potential high-affinity BZD binding sites, although small sequence differences between subunits may alter binding affinity to individual molecules. The 4 and 6 subunits, in which an otherwise conserved histidine is replaced by arginine, do not bind traditional BZD ligands such as diazepam and hence are considered "diazepam-insensitive". GABA binding results in a series of conformational changes in the ECDs of GABAAR subunits, "locking" each to its neighbouring - interface. The binding of alprazolam in the high-affinity BZD site stabilizes the +/- interface and facilitates the conformational changes that lead to pore opening, hence functioning as a positive allosteric modulator. The exact manner in which GABAAR allosteric modulation mediates the therapeutic and unwanted effects of benzodiazepines remains unclear. Earlier studies suggested that the primary factor was the subunit composition, with 1-containing receptors mediating the sedative effects, 2/3-containing receptors the anxiolytic effects, and 5-containing receptors the memory effects of benzodiazepines. More recent studies suggest a more complex set of factors including subunit composition, physiological location, neuronal circuit, and nerve cell type. To further complicate matters, there may be up to five distinct BZD binding sites on GABAARs, with site 1 corresponding to the classical high-affinity +/- interface. The effects of binding at sites 2-4 are not fully understood and likely impart greater complexity to benzodiazepine pharmacological action.

    In animals, benzodiazepines protect against seizures induced by electrical stimulation and by pentylenetetrazol; benzodiazepines appear to act, at least partly, by augmenting presynaptic inhibition. The drugs suppress the spread of seizure activity but do not abolish the abnormal discharge from a focus in experimental models of epilepsy. In usual doses, benzodiazepines appear to have very little effect on the autonomic nervous system, respiration, or the cardiovascular system. /Benzodiazepines/

    McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 2379

    CNS agents of the 1,4 benzodiazepine class presumably exert their effects by binding at stereo specific receptors at several sites within the central nervous system. Their exact mechanism of action is unknown. Clinically, all benzodiazepines cause a dose-related central nervous system depressant activity varying from mild impairment of task performance to hypnosis.

    NIH; DailyMed. Current Medication Information for Xanax (Alprazolam) Tablet (Updated: October 2016). Available from, as of October 28, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388e249d-b9b6-44c3-9f8f-880eced0239f

    Anxiolytic and possibly paradoxical CNS stimulatory effects of benzodiazepines are postulated to result from release of previously suppressed responses (disinhibition). After usual doses of benzodiazepines for several days, the drugs cause a moderate decrease in rapid eye movement (REM) sleep. REM rebound does not occur when the drugs are withdrawn. Stage 3 and 4 sleep are markedly reduced by usual doses of the drugs; the clinical importance of these sleep stage alterations has not been established. /Benzodiazepines/

    McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 2379

    Benzodiazepines appear to produce skeletal muscle relaxation predominantly by inhibiting spinal polysynaptic afferent pathways, but the drugs may also inhibit monosynaptic afferent pathways. The drugs may inhibit monosynaptic and polysynaptic reflexes by acting as inhibitory neuronal transmitters or by blocking exitatory synaptic transmission. The drugs may also directly depress motor nerve and muscle function. /Benzodiazepines/

    McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 2379

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    Alprazolam (Ph. Eur.)

    Date of Issue : 2022-06-22

    Valid Till : 2025-07-28

    Written Confirmation Number : WC-0117

    Address of the Firm : Unit-VII, Plot No. 14, 99, &100, IDA, Pashamylaram, Phase-II, Patancheru,Sangare...

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    KDMF

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    Malladi Drugs & Pharmaceuticals Lim...

    India
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    Virtual BoothMalladi is a leader in Ephedrine, Pseudoephedrine Salts & Phenylephrine HCl // USFDA, EDQM, ANSM, KFDA, and TGA inspected.

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    Alprazolam

    Registrant Name : Kukjeon Pharmaceutical Co., Ltd.

    Registration Date : 2021-06-14

    Registration Number : 20210614-209-J-1016

    Manufacturer Name : Malladi Drugs & Pharmaceutic...

    Manufacturer Address : Unit-III, 7B&7C, Sipcot Industrial Complex, Ranipet-632 403, Ranipet District, India

    Malladi

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    Cambrex Corporation

    U.S.A
    Pharma, Lab & Chemical Expo
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    Cambrex Corporation

    U.S.A
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    Alprazolam

    Registrant Name : Samoh Pharmaceutical Co., Ltd.

    Registration Date : 2018-10-28

    Registration Number : 20181028-209-J-268

    Manufacturer Name : Cambrex Profarmaco Milano Sr...

    Manufacturer Address : Via Curiel, 34 - 20067 Paullo, Milano, Italy

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    Centaur Pharmaceuticals

    India
    Pharma, Lab & Chemical Expo
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    Centaur Pharmaceuticals

    India
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    Alprazolam

    Registrant Name : Hana Pharmaceutical Co., Ltd.

    Registration Date : 2021-03-10

    Registration Number : 20180820-209-J-39(1)

    Manufacturer Name : Centaur Pharmaceuticals Priv...

    Manufacturer Address : Plot No. 75/76 & 76/1, Chikhloli MIDC, Ambernath (west). Dist.-Thane-421 501, Maharas...

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    Centaur Pharmaceuticals

    India
    Pharma, Lab & Chemical Expo
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    Centaur Pharmaceuticals

    India
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    Alprazolam

    Registrant Name : Aging Life Science Co., Ltd.

    Registration Date : 2018-08-20

    Registration Number : 20180820-209-J-39

    Manufacturer Name : Centaur Pharmaceuticals Priv...

    Manufacturer Address : Plot No. 75/76 & 76/1, Chikhloli MIDC, Ambernath (west). Dist.-Thane-421 501, Maharas...

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    Lake Chemicals

    India
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Lake Chemicals

    India
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    Alprazolam

    Registrant Name : Unimed Pharmaceutical Co., Ltd.

    Registration Date : 2021-12-03

    Registration Number : 20210518-209-J-715(1)

    Manufacturer Name : Lake Chemicals Pvt Ltd

    Manufacturer Address : No. 21M, Attibele Industrial Area, Anekal Taluk Bangalore-562 107, India

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    Lake Chemicals

    India
    Pharma, Lab & Chemical Expo
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    Lake Chemicals

    India
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    Alprazolam

    Registrant Name : Kwangdong Pharmaceutical Co., Ltd.

    Registration Date : 2021-05-18

    Registration Number : 20210518-209-J-715

    Manufacturer Name : Lake Chemicals Pvt Ltd

    Manufacturer Address : No. 21M, Attibele Industrial Area, Anekal Taluk Bangalore-562 107, India

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    Pfizer Inc

    U.S.A
    Pharma, Lab & Chemical Expo
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    Pfizer Inc

    U.S.A
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    Alprazolam

    Registrant Name : Beatrice Korea Co., Ltd.

    Registration Date : 2021-03-16

    Registration Number : 20210316-209-J-884

    Manufacturer Name : Pharmacia & Upjohn Company

    Manufacturer Address : 7000 Portage Road, Kalamazoo, Michigan 49001, USA

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    NDC API

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    Malladi Drugs & Pharmaceuticals Lim...

    India
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    Virtual BoothMalladi is a leader in Ephedrine, Pseudoephedrine Salts & Phenylephrine HCl // USFDA, EDQM, ANSM, KFDA, and TGA inspected.

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    ALPRAZOLAM

    NDC Package Code : 57218-312

    Start Marketing Date : 2008-01-01

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    Malladi

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    02

    Fermion Oy

    Finland
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    ALPRAZOLAM

    NDC Package Code : 12780-4630

    Start Marketing Date : 1991-04-04

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

    fermion

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    03

    Cambrex Profarmaco Milano Srl

    U.S.A
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Cambrex Profarmaco Milano Srl

    U.S.A
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    ALPRAZOLAM

    NDC Package Code : 12828-0040

    Start Marketing Date : 1988-04-04

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    Centaur Pharmaceuticals Private Lim...

    India
    Pharma, Lab & Chemical Expo
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    Centaur Pharmaceuticals Private Lim...

    India
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    ALPRAZOLAM

    NDC Package Code : 64330-013

    Start Marketing Date : 2007-08-30

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    05

    Pharmacia and Upjohn Company LLC

    U.S.A
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Pharmacia and Upjohn Company LLC

    U.S.A
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    ALPRAZOLAM

    NDC Package Code : 0009-5144

    Start Marketing Date : 2014-07-03

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    06

    R.L.Fine Chem Private Limited

    India
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    R.L.Fine Chem Private Limited

    India
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    ALPRAZOLAM

    NDC Package Code : 71554-013

    Start Marketing Date : 2019-05-13

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    07

    Tianish Laboratories Private Limite...

    India
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Tianish Laboratories Private Limite...

    India
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    ALPRAZOLAM

    NDC Package Code : 84206-0108

    Start Marketing Date : 2015-01-20

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    Tianish Laboratories Private Limite...

    India
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Tianish Laboratories Private Limite...

    India
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    ALPRAZOLAM

    NDC Package Code : 84206-0005

    Start Marketing Date : 2024-07-30

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    MYLAN LABORATORIES LIMITED

    U.S.A
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    MYLAN LABORATORIES LIMITED

    U.S.A
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    ALPRAZOLAM

    NDC Package Code : 65015-634

    Start Marketing Date : 2015-01-20

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    Listed Suppliers

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    Malladi Drugs & Pharmaceuticals Lim...

    India
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    Virtual BoothMalladi is a leader in Ephedrine, Pseudoephedrine Salts & Phenylephrine HCl // USFDA, EDQM, ANSM, KFDA, and TGA inspected.

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    Alprazolam

    About the Company : Malladi Drugs & Pharmaceuticals Ltd was founded in 1980 by microbiologist Mr. M L N Sastry. Within a few years, Malladi established itself as a leader in manufacturing ephedrine an...

    Malladi Drugs & Pharmaceuticals Ltd was founded in 1980 by microbiologist Mr. M L N Sastry. Within a few years, Malladi established itself as a leader in manufacturing ephedrine and pseudoephedrine salts. Today, it is the leading manufacturer of APIs in the cough and cold segment. It also has a dominant presence in several therapeutic segments like antihistamines, anti-convulsants, anti-depressants and anxiolytics (CNS). Malladi exports its products to around 60 countries and over 85% of its revenue is generated from exports. Its manufacturing facilities have been approved by the FDA, EDQM, KFDA, TGA and various other regulatory agencies.
    Malladi

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    LGM Pharma

    U.S.A
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    Virtual BoothLGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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    Alprazolam

    About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

    LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
    LGM Pharma CB

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    03

    Fermion Oy

    Finland
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    Alprazolam

    About the Company : Fermion is fully owned subsidiary of Orion Corporation & headquartered in Espoo, Finland. Together with Orion we are a fully integrated CDMO & offer services covering both APIs & F...

    Fermion is fully owned subsidiary of Orion Corporation & headquartered in Espoo, Finland. Together with Orion we are a fully integrated CDMO & offer services covering both APIs & Formulations. API portfolio consists of >30 generic APIs & >10 NCEs & 2 mfg. sites as well as R&D facilities are all located in Finland. Fermion has invested & expanded capabilities in the production of HPAPIs. Drug product CMO services include hormonal & non-hormonal semi-solids, cytotoxic oral solids & packaging. We have 3 mfg. sites & one packaging center for drug products at Orion.
    fermion

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    HRV Global Life Sciences

    India
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    Virtual BoothHRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

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    Alprazolam

    About the Company : HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It...

    HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It offers services such as sourcing, manufacturing & supply, helping partners enter new markets worldwide. Its strong partnerships with major players in the pharma and food additive industries help HRV Global effectively promote projects and products. HRV Global represents over 30 large Indian drugmakers, primarily targeting Europe, the US & the Middle East markets. Headquartered in India, HRV Global has offices in the US, Switzerland, Dubai, Lithuania & Turkey.
    HRV Global Life Sciences

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    Biotechnica DWC

    Algeria
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Biotechnica DWC

    Algeria
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    Alprazolam

    About the Company : BIOTECHNICA DWC LLC has carved a niche for itself in providing value added compliance, regulatory qualification, project management and GDP guidance services to pharma companies al...

    BIOTECHNICA DWC LLC has carved a niche for itself in providing value added compliance, regulatory qualification, project management and GDP guidance services to pharma companies all over the world. Biotechnica is an integrated global solution provider from design to implementation of industrial projects in the areas of Pharmaceuticals,Agri-food ,Cosmetics and Nutrition. With more than 25 years of experience in the assembly of plants, particularly in the pharmaceutical sector, we accompany our customers in the various stages of their projects – E-CTD Dossieers – Raw Materiels – Equipements – Accessories – Packaging – Distribution.
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    06

    Cambrex Corporation

    U.S.A
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Cambrex Corporation

    U.S.A
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    Alprazolam

    About the Company : Driven by passion, our pharmaceutical products, expertise and technologies accelerate our customers’ small molecule therapeutics into markets across the world. With over 35 years...

    Driven by passion, our pharmaceutical products, expertise and technologies accelerate our customers’ small molecule therapeutics into markets across the world. With over 35 years of API development and manufacturing expertise, a growing team of more than 1,200 experts and a strong presence in the USA and Europe, we are tried and trusted across branded and generic API markets. We put all of our energy and experience into being your partner of choice. We create value for customers through manufacturing excellence, reliable quality and innovative science. Our people are the experts that our customers enjoy working with.
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    07

    Dishman Carbogen Amcis

    India
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Dishman Carbogen Amcis

    India
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    Alprazolam

    About the Company : We have been supporting the pharmaceutical and biopharmaceutical industries with drug development for over 30 years, assisting our clients in developing and bringing new drugs to m...

    We have been supporting the pharmaceutical and biopharmaceutical industries with drug development for over 30 years, assisting our clients in developing and bringing new drugs to market while improving the lives of their patients across the world. Our objective is to help our customers create a better world as the partner of choice to develop and manufacture complex and challenging substances, highly potent active ingredients, and breaking new ground with innovative vitamin, healthcare, and industrial products.
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    08

    Formil Quimica Ltd

    Brazil
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    Formil Quimica Ltd

    Brazil
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    Alprazolam

    About the Company : Formil QuImica Ltd is a Brazilian company located in BaruerI - SP. We produce through chemical synthesis or extraction and commercialize API (Active Pharmaceutical Ingredient) on l...

    Formil QuImica Ltd is a Brazilian company located in BaruerI - SP. We produce through chemical synthesis or extraction and commercialize API (Active Pharmaceutical Ingredient) on local and external markets focused on Pharmaceuticals, Veterinary and Cosmetic companies. Our expertise is based in constant innovation research, driven through our R&D that works independently and with cooperation with Universities, Research Centers and also with customer's partnership. Formil produces under rigorous GMP procedures that can guarantee the quality and reliability of our product, processes and services.
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    09

    IIQUIAP

    Mexico
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    IIQUIAP

    Mexico
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    Pharma, Lab & Chemical Expo
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    Alprazolam

    About the Company : We are a 100% Mexican company certified in Good Manufacturing Practices (GMP). We have been in the business of manufacturing Active Pharmaceutical Ingredients (API´s) for more tha...

    We are a 100% Mexican company certified in Good Manufacturing Practices (GMP). We have been in the business of manufacturing Active Pharmaceutical Ingredients (API´s) for more than 10 years. We offer Research & Development services to the Pharmaceutical Industry. Research, develop and innovate pharmaceutical ingredients and drugs in compliance with all current national and international health regulations to create products that offer more advantages than those currently available in the market.
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    R L Fine Chem

    India
    Pharma, Lab & Chemical Expo
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    R L Fine Chem

    India
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    Pharma, Lab & Chemical Expo
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    Alprazolam

    About the Company : Established in 1984, R L Fine Chem Pvt. Ltd. is one of the fastest growing API companies, with a leadership position in several APIs such as antihistamines, antidepressants and mus...

    Established in 1984, R L Fine Chem Pvt. Ltd. is one of the fastest growing API companies, with a leadership position in several APIs such as antihistamines, antidepressants and muscle relaxants. Acquired by private equity groups in 2016, it is one of India’s leading manufacturers of psychotropic substances. It supplies over 60 APIs to customers in more than 62 countries from FDA and EU-approved locations. R L Fine Chem is a technology-driven company with a focus on the in-house manufacture of key intermediates for our APIs. The company currently operates out of four facilities in the Indian states of Karnataka and Andhra Pradesh.
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TELANGANA,? 500096, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730745000,"product":"PHARMACEUTICAL RAW MATERIAL ALPRAZOLAM PH EUR BATCH NO.800024012A MFG DATE.AUGUST-2024 EXP DATE.JULY-2029","address":"5TH FLOOR,LAXMINARAYAN COMPLEX","city":"BANGALORE, KARNATAKA","supplier":"LAKE CHEMICALS PRIVATE ","supplierCountry":"INDIA","foreign_port":"TAIPEI","customer":"TO THE ORDER OF","customerCountry":"TAIWAN","quantity":"17.00","actualQuantity":"17","unit":"KGS","unitRateFc":"775","totalValueFC":"12659.5","currency":"USD","unitRateINR":62841.87764705882,"date":"05-Nov-2024","totalValueINR":"1068311.92","totalValueInUsd":"12659.5","indian_port":"Bangalore Air","hs_no":"29339100","bill_no":"5359935","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"5TH FLOOR,LAXMINARAYAN COMPLEX, BANGALORE, KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732213800,"product":"ALPRAZOLAM USP (EXPORT PERMIT NO.P-EXP-16216\/2024 DT.02\/11\/2024,IMPORT PERMIT NO.FP.03.04.SPIP\/IV\/576\/24 DT.26\/09\/2024)","address":"CENTAUR HOUSE, SHANTI NAGAR,","city":"MUMBAI ,MAHARASHTRA","supplier":"CENTAUR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"TO THE ORDER OF","customerCountry":"INDONESIA","quantity":"23.00","actualQuantity":"23","unit":"KGS","unitRateFc":"975","totalValueFC":"21952.4","currency":"USD","unitRateINR":80544.65217391304,"date":"22-Nov-2024","totalValueINR":"1852527","totalValueInUsd":"21952.4","indian_port":"Bombay Air","hs_no":"29339100","bill_no":"5822643","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"CENTAUR HOUSE, SHANTI NAGAR,, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732300200,"product":"PHARMACEUTICAL RAW MATERIAL- ALPRAZOLAMPH EUR , BATCH NO : 800024005C MFG DATE:OCTOBER-2024 EXP DATE:SEPTEMBER-2029","address":"5TH FLOOR,LAXMINARAYAN COMPLEX","city":"BANGALORE, KARNATAKA","supplier":"LAKE CHEMICALS PRIVATE ","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"TO THE ORDER OF","customerCountry":"ARGENTINA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"595","totalValueFC":"57588.1","currency":"USD","unitRateINR":48597.529999999999,"date":"23-Nov-2024","totalValueINR":"4859753","totalValueInUsd":"57588.1","indian_port":"Bangalore Air","hs_no":"29339100","bill_no":"5859028","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"5TH FLOOR,LAXMINARAYAN COMPLEX, BANGALORE, KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732559400,"product":"ALPRAZOLAM USP [EXPORT PERMIT NO.P\/EXP-15959\/2024 DTD.16\/10\/2024,IMPORT PERMIT NO.5684\/24 DTD.19\/09\/2024","address":"CENTAUR HOUSE, SHANTI NAGAR,","city":"MUMBAI ,MAHARASHTRA","supplier":"CENTAUR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"HONG KONG","customer":"TO THE ORDER OF","customerCountry":"HONG KONG","quantity":"3.80","actualQuantity":"3.8","unit":"KGS","unitRateFc":"950","totalValueFC":"3292.9","currency":"USD","unitRateINR":73127.894736842107,"date":"26-Nov-2024","totalValueINR":"277886","totalValueInUsd":"3292.9","indian_port":"Bombay Air","hs_no":"29339100","bill_no":"5908177","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"CENTAUR HOUSE, SHANTI NAGAR,, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1638124200,"product":"ALPRAZOLAM 1MG PLACEBO POWDER (QTY:50 GMS)","address":"PLOT NO.2, MAITRIVIHAR BEHIND MAITRIVANAM, AMEERPET","city":"HYDERABAD","supplier":"VIATRIS","supplierCountry":"AUSTRALIA","foreign_port":"NA","customer":"AUROBINDO PHARMA LIMITED","customerCountry":"INDIA","quantity":"0.05","actualQuantity":"0.05","unit":"KGS","unitRateFc":"500","totalValueFC":"22.4","currency":"AUD","unitRateINR":"33430.6","date":"29-Nov-2021","totalValueINR":"1671.53","totalValueInUsd":"22.4","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"6450757","productDescription":"API","marketType":"REGULATED MARKET","country":"AUSTRALIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO.2, MAITRIVIHAR BEHIND MAITRIVANAM, AMEERPET"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1638556200,"product":"ALPRAZOLAM RELATED COMPOUND A(QTY 1 X 30 MG PRICE: USD 860)(FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"WASHINGTON DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.00003","unit":"KGS","unitRateFc":"28666666.7","totalValueFC":"915.7","currency":"USD","unitRateINR":"2302288333","date":"04-Dec-2021","totalValueINR":"69068.65","totalValueInUsd":"915.7","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"6539094","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON DULLES I","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1643049000,"product":"ALPRAZOLAM","address":"12TH FLOOR, COMMERZ II,,INTERNATIO NAL BUSNESS PARK,OBEROI","city":"GARDEN CITY OFF WESTERN EXPR HIGHWA","supplier":"CAMBREX CORPORATION","supplierCountry":"ITALY","foreign_port":"SEGRATE AIRPRT MILAN","customer":"TEVA PHARMACEUTICAL INDUSTRIES","customerCountry":"INDIA","quantity":"325.00","actualQuantity":"325","unit":"KGS","unitRateFc":"1200","totalValueFC":"394222.6","currency":"USD","unitRateINR":"90360","date":"25-Jan-2022","totalValueINR":"29367000","totalValueInUsd":"394222.6","indian_port":"BOMBAY AIR","hs_no":"29339100","bill_no":"7224295","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"SEGRATE AIRPRT MILAN","supplierAddress":"","customerAddress":"12TH FLOOR, COMMERZ II,,INTERNATIO NAL BUSNESS PARK,OBEROI"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670437800,"product":"ALPRAZOLAM MICRONIZED (PSYCHOTROPIC SUBSTANCE- IMPORT AUTHORIZATION NO. P-IMP-10607\/2022) DTD.23.11.2022 CBN LIC. SR. NO","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"CAMBREX CORPORATION","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"PAR PHARMACEUTICAL","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"4000","totalValueFC":"19901.4","currency":"USD","unitRateINR":"328000","date":"08-Dec-2022","totalValueINR":"1640000","totalValueInUsd":"19901.4","indian_port":"Indore-EPZ\/SEZ","hs_no":"29339100","bill_no":"1008173","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"N\/A","supplierAddress":"VIA.E CURIEL 34-20067 PAULLO MI-IT ALY , , Italy Italy","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1680546600,"product":"ALPRAZOLAM","address":"12TH FLOOR, COMMERZ II,,INTERNATIO NAL BUSNESS PARK,OBEROI","city":"GARDEN CITY OFF WESTERN EXPR HIGHWA","supplier":"CAMBREX CORPORATION","supplierCountry":"ITALY","foreign_port":"NA","customer":"TEVA PHARMACEUTICAL INDUSTRIES","customerCountry":"INDIA","quantity":"293.45","actualQuantity":"293.45","unit":"KGS","unitRateFc":"1200","totalValueFC":"359643.2","currency":"USD","unitRateINR":"100440","date":"04-Apr-2023","totalValueINR":"29474118","totalValueInUsd":"359643.2","indian_port":"BOMBAY AIR","hs_no":"29339100","bill_no":"5374374","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"12TH FLOOR, COMMERZ II,,INTERNATIO NAL BUSNESS PARK,OBEROI"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1685903400,"product":"ALPRAZOLAM MICRONIZED","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"CAMBREX CORPORATION","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"PAR PHARMACEUTICAL","customerCountry":"INDIA","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"6000","totalValueFC":"24351.5","currency":"USD","unitRateINR":"500400","date":"05-Jun-2023","totalValueINR":"2001600","totalValueInUsd":"24351.5","indian_port":"Indore-EPZ\/SEZ","hs_no":"29339100","bill_no":"1003570","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1707417000,"product":"ALPRAZOLAM ,BATCH: 0880112,CAS 28981-97-7","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"CAMBREX PROFARNACO MILANO S.R.L.","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"SANDOZ B2B","customerCountry":"INDIA","quantity":"7.02","actualQuantity":"7.02","unit":"KGS","unitRateFc":"1500","totalValueFC":"10653.9","currency":"USD","unitRateINR":"125925","date":"09-Feb-2024","totalValueINR":"883993.5","totalValueInUsd":"10653.9","indian_port":"Bombay Air","hs_no":"29280010","bill_no":"2062267","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA E.CURLEL, 34-20067 PAULIO MI,ItalySDNF Italy","customerAddress":"SANDOZ HOUSE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1707417000,"product":"ALPRAZOLAM BATCH:0880112 CAS28997-97-7","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"CAMBREX PROFARNACO MILANO S.R.L.","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"SANDOZ B2B","customerCountry":"INDIA","quantity":"10.53","actualQuantity":"10.525","unit":"KGS","unitRateFc":"1500","totalValueFC":"15973.2","currency":"USD","unitRateINR":"125925","date":"09-Feb-2024","totalValueINR":"1325360.63","totalValueInUsd":"15973.2","indian_port":"Bombay Air","hs_no":"29280010","bill_no":"2062267","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA E.CURLEL, 34-20067 PAULIO MI,ItalySDNF Italy","customerAddress":"SANDOZ HOUSE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1707417000,"product":"ALPRAZOLAM BATCH:0880112 CAS28997-97-7","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"CAMBREX PROFARNACO MILANO S.R.L.","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"SANDOZ B2B","customerCountry":"INDIA","quantity":"10.53","actualQuantity":"10.53","unit":"KGS","unitRateFc":"1500","totalValueFC":"15980.8","currency":"USD","unitRateINR":"125925","date":"09-Feb-2024","totalValueINR":"1325990.25","totalValueInUsd":"15980.8","indian_port":"Bombay Air","hs_no":"29280010","bill_no":"2062267","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA E.CURLEL, 34-20067 PAULIO MI,ItalySDNF Italy","customerAddress":"SANDOZ HOUSE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1707935400,"product":"ALPRAZOLAM ,BATCH: 0880112,CAS 28981-97-7","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"CAMBREX PROFARNACO MILANO S.R.L.","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"SANDOZ B2B","customerCountry":"INDIA","quantity":"7.02","actualQuantity":"7.02","unit":"KGS","unitRateFc":"1500","totalValueFC":"10653.9","currency":"USD","unitRateINR":"125925","date":"15-Feb-2024","totalValueINR":"883993.5","totalValueInUsd":"10653.9","indian_port":"Bombay Air","hs_no":"29280010","bill_no":"2151614","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA E.CURLEL, 34-20067 PAULIO MI, ItalySDNF Italy","customerAddress":"SANDOZ HOUSE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709145000,"product":"ALPRAZOLAM BATCH:0880112 CAS28997-97-7","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"CAMBREX PROFARNACO MILANO S.R.L.","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"SANDOZ B2B","customerCountry":"INDIA","quantity":"3.51","actualQuantity":"3.51","unit":"KGS","unitRateFc":"1500","totalValueFC":"5326.9","currency":"USD","unitRateINR":"125925","date":"29-Feb-2024","totalValueINR":"441996.75","totalValueInUsd":"5326.9","indian_port":"Bombay Air","hs_no":"29280010","bill_no":"2365437","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA E.CURLEL, 34-20067 PAULIO MI,ItalySDNF Italy","customerAddress":"SANDOZ HOUSE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1712860200,"product":"ALPRAZOLAM MICRONIZED BATCH NO:0858904","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"CAMBREX CORPORATION","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"PAR PHARMACEUTICAL","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"6000","totalValueFC":"12121.1","currency":"USD","unitRateINR":"506100","date":"12-Apr-2024","totalValueINR":"1012200","totalValueInUsd":"12121.1","indian_port":"Madras Air","hs_no":"29339990","bill_no":"2988992","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"MILAN - MALPENSA","supplierAddress":"34 VIA EUGENIO CURIELPAULLOMILAN 20067 ITALY","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729276200,"product":"ALPRAZOLAM (BATCH 0911324) (CBN PERMIT NO. P\/IMP-10270\/2024DATED 02.05.2024 VALID UPTO 02.11.2024)","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"CAMBREX PROFARNACO MILANO S.R.L.","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"SANDOZ B2B","customerCountry":"INDIA","quantity":"75.00","actualQuantity":"75","unit":"KGS","unitRateFc":"1500","totalValueFC":"113736.4","currency":"USD","unitRateINR":"127425","date":"19-Oct-2024","totalValueINR":"9556875","totalValueInUsd":"113736.4","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"6211666","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"VIA E.CURLEL, 34-20067 PAULIO MI I taly SDNF Italy","customerAddress":"SANDOZ HOUSE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729276200,"product":"ALPRAZOLAM (BATCH 0911324) (CBN PERMIT NO. P\/IMP-13185\/2024DATED 13.09.2024 VALID UPTO 13.03.2025)","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"CAMBREX PROFARNACO MILANO S.R.L.","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"SANDOZ B2B","customerCountry":"INDIA","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"1500","totalValueFC":"227472.7","currency":"USD","unitRateINR":"127425","date":"19-Oct-2024","totalValueINR":"19113750","totalValueInUsd":"227472.7","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"6211666","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"VIA E.CURLEL, 34-20067 PAULIO MI I taly SDNF Italy","customerAddress":"SANDOZ HOUSE"}]
    05-Jan-2021
    26-Nov-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    Europe

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    01

    WINTHROP PHARM.ITALIA Srl

    U.S.A
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    Regulatory Info :

    Registration Country : Italy

    Alprazolam

    Brand Name : Alprazolam

    Dosage Form :

    Dosage Strength : Gtt Os 20 Ml 0.75 Mg/Ml  

    Packaging :

    Approval Date :

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    Regulatory Info :

    Registration Country : Italy

    Sanofi

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    02

    Orion Corporation

    Finland
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    Regulatory Info :

    Registration Country : Sweden

    alprazolam

    Brand Name : Alprazolam Orion

    Dosage Form : TABLET

    Dosage Strength : 0.25 MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Sweden

    Fermion Orion Company Banner

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    03

    Orion Corporation

    Finland
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    Regulatory Info :

    Registration Country : Sweden

    alprazolam

    Brand Name : Alprazolam Orion

    Dosage Form : TABLET

    Dosage Strength : 0.5 MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Sweden

    Fermion Orion Company Banner

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    04

    Orion Corporation

    Finland
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    Regulatory Info :

    Registration Country : Sweden

    alprazolam

    Brand Name : Alprazolam Orion

    Dosage Form : TABLET

    Dosage Strength : 1 MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Sweden

    Fermion Orion Company Banner

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    05

    Orion Corporation

    Finland
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    Regulatory Info :

    Registration Country : Sweden

    alprazolam

    Brand Name : Alprazolam Orion

    Dosage Form : TABLET

    Dosage Strength : 2 MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Sweden

    Fermion Orion Company Banner

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    06

    Pfizer

    U.S.A
    Pharma, Lab & Chemical Expo
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    Pfizer

    U.S.A
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    Regulatory Info :

    Registration Country : Sweden

    alprazolam

    Brand Name : Xanax

    Dosage Form : TABLET

    Dosage Strength : 1 MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Sweden

    blank

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    07

    Pfizer AS

    U.S.A
    Pharma, Lab & Chemical Expo
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    Pfizer AS

    U.S.A
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    Flag U.S.A
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Norway

    Alprazolam

    Brand Name : Xanor

    Dosage Form : Antic-calc Tablet

    Dosage Strength : 1 mg

    Packaging : Blister

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

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    08

    SOLVAY PHARMA SpA

    Country
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    SOLVAY PHARMA SpA

    Country
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
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    Regulatory Info :

    Registration Country : Italy

    Alprazolam

    Brand Name : Frontal

    Dosage Form :

    Dosage Strength : 20 Cpr 0.25 Mg  

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Italy

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    09

    SOLVAY PHARMA SpA

    Country
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    SOLVAY PHARMA SpA

    Country
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Country
    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : Italy

    Alprazolam

    Brand Name : Frontal

    Dosage Form :

    Dosage Strength : 20 Cpr 0.50 Mg  

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Italy

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    10

    Country
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Country
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Flag Country
    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : Spain

    Alprazolam

    Brand Name : Alprazolam Ratiopharm 0.25Mg 30 Tablets Efg

    Dosage Form : Tablet

    Dosage Strength : 0.25 Mg/Tablet

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Spain

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    Canada

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    01

    Orion Corporation

    Finland
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Flag Finland
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Generic

    Registration Country : Canada

    Alprazolam

    Brand Name :

    Dosage Form : TABLET

    Dosage Strength : 0.25MG

    Packaging :

    Approval Date :

    Application Number : 74085

    Regulatory Info : Generic

    Registration Country : Canada

    Fermion Orion Company Banner

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    02

    Orion Corporation

    Finland
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
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    Flag Finland
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Generic

    Registration Country : Canada

    Alprazolam

    Brand Name :

    Dosage Form : TABLET

    Dosage Strength : 0.5MG

    Packaging :

    Approval Date :

    Application Number : 78056

    Regulatory Info : Generic

    Registration Country : Canada

    Fermion Orion Company Banner

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    03

    Orion Corporation

    Finland
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Flag Finland
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Generic

    Registration Country : Canada

    Alprazolam

    Brand Name :

    Dosage Form : TABLET

    Dosage Strength : 1MG

    Packaging :

    Approval Date :

    Application Number : 74294

    Regulatory Info : Generic

    Registration Country : Canada

    Fermion Orion Company Banner

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    04

    Orion Corporation

    Finland
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Flag Finland
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Generic

    Registration Country : Canada

    Alprazolam

    Brand Name :

    Dosage Form : TABLET

    Dosage Strength : 2MG

    Packaging :

    Approval Date :

    Application Number : 74085

    Regulatory Info : Generic

    Registration Country : Canada

    Fermion Orion Company Banner

    Portfolio PDF

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    05

    APOTEX INC

    Canada
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    APOTEX INC

    Canada
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Canada
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

    ALPRAZOLAM

    Brand Name : APO-ALPRAZ

    Dosage Form : TABLET

    Dosage Strength : 1MG

    Packaging : 100

    Approval Date :

    Application Number : 2243611

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

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    06

    APOTEX INC

    Canada
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    APOTEX INC

    Canada
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Canada
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

    ALPRAZOLAM

    Brand Name : APO-ALPRAZ TS

    Dosage Form : TABLET

    Dosage Strength : 2MG

    Packaging : 100

    Approval Date :

    Application Number : 2243612

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

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    07

    BGP PHARMA ULC

    Canada
    Pharma, Lab & Chemical Expo
    Not Confirmed
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    BGP PHARMA ULC

    Canada
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Canada
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

    ALPRAZOLAM

    Brand Name : XANAX

    Dosage Form : TABLET

    Dosage Strength : 1MG

    Packaging :

    Approval Date :

    Application Number : 723770

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

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    08

    Natco Pharma Limited

    India
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Natco Pharma Limited

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

    Alprazolam

    Brand Name : NAT-ALPRAZOLAM

    Dosage Form : Tablet

    Dosage Strength : 0.5MG

    Packaging : 100/500/1000

    Approval Date :

    Application Number :

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

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    09

    Natco Pharma Limited

    India
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Natco Pharma Limited

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

    Alprazolam

    Brand Name : NAT-ALPRAZOLAM

    Dosage Form : Tablet

    Dosage Strength : 1MG

    Packaging : 100/500/1000

    Approval Date :

    Application Number :

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

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    Digital Content

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    10

    PRO DOC LIMITEE

    Canada
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    PRO DOC LIMITEE

    Canada
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Canada
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

    ALPRAZOLAM

    Brand Name : PRO-ALPRAZOLAM

    Dosage Form : TABLET

    Dosage Strength : 0.25MG

    Packaging : 100/1000

    Approval Date :

    Application Number : 1908189

    Regulatory Info : Targeted (CDSA IV)

    Registration Country : Canada

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    Australia

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    01

    Aspen Pharmacare Australia Pty Limited

    South Africa
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag South Africa
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Australia

    alprazolam

    Brand Name : Alprax 1

    Dosage Form :

    Dosage Strength :

    Packaging : 10

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

    Aspen API Comapny Banner

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    02

    Aspen Pharmacare Australia Pty Limited

    South Africa
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag South Africa
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Australia

    alprazolam

    Brand Name : Alprax 0.5

    Dosage Form :

    Dosage Strength :

    Packaging : 10

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

    Aspen API Comapny Banner

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    03

    Alphapharm Pty Ltd

    Australia
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Alphapharm Pty Ltd

    Australia
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Australia
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Australia

    alprazolam

    Brand Name : Kalma 1

    Dosage Form :

    Dosage Strength :

    Packaging : 10

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

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    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

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    04

    Alphapharm Pty Ltd

    Australia
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Alphapharm Pty Ltd

    Australia
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Australia
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Australia

    alprazolam

    Brand Name : Kalma 0.5

    Dosage Form :

    Dosage Strength :

    Packaging : 10

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

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    Digital Content

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    05

    Alphapharm Pty Ltd

    Australia
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Alphapharm Pty Ltd

    Australia
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Australia
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Australia

    alprazolam

    Brand Name : Kalma 0.25

    Dosage Form :

    Dosage Strength :

    Packaging : 10

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

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    Listed Dossiers

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    01

    Strides Pharma Science

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : India

    Alprazolam

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 0.25MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Strides Pharma Science

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    01

    Strides Pharma Science

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Alprazolam

    Dosage : Tablet

    Dosage Strength : 0.25MG

    Brand Name :

    Approval Date :

    Application Number :

    Registration Country : India

    Strides Pharma Science

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    02

    Strides Pharma Science

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : India

    Alprazolam

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 0.5MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Strides Pharma Science

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

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    02

    Strides Pharma Science

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Alprazolam

    Dosage : Tablet

    Dosage Strength : 0.5MG

    Brand Name :

    Approval Date :

    Application Number :

    Registration Country : India

    Strides Pharma Science

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    03

    Strides Pharma Science

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : India

    Alprazolam

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 1MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Strides Pharma Science

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

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    03

    Strides Pharma Science

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Alprazolam

    Dosage : Tablet

    Dosage Strength : 1MG

    Brand Name :

    Approval Date :

    Application Number :

    Registration Country : India

    Strides Pharma Science

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    04

    Strides Pharma Science

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : India

    Alprazolam

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 2MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Strides Pharma Science

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    04

    Strides Pharma Science

    India
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Alprazolam

    Dosage : Tablet

    Dosage Strength : 2MG

    Brand Name :

    Approval Date :

    Application Number :

    Registration Country : India

    Strides Pharma Science

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

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    05

    Bio Labs

    Pakistan
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Bio Labs

    Pakistan
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Pakistan
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Generic

    Registration Country : Pakistan

    Alprazolam

    Brand Name : Bizolam .

    Dosage Form : TABLET

    Dosage Strength : 0.25MG

    Packaging : 3 x 10's

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Pakistan

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    05

    Bio Labs

    Pakistan
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Bio Labs

    Pakistan
    arrow
    Pharma, Lab & Chemical Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Pakistan
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging : 3 x 10's

    Regulatory Info : Generic

    Alprazolam

    Dosage : TABLET

    Dosage Strength : 0.25MG

    Brand Name : Bizolam .

    Approval Date :

    Application Number :

    Registration Country : Pakistan

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    06

    Biodeal Pharmaceuticals

    India
    Pharma, Lab & Chemical Expo
    Not Confirmed
    arrow

    Biodeal Pharmaceuticals

    India
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    Alprazolam

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    Biodeal Pharmaceuticals

    India
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    Biodeal Pharmaceuticals

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    Registration Country : India

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    07

    Poddar Pharmaceuticals

    India
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    Poddar Pharmaceuticals

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    Alprazolam

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    07

    Poddar Pharmaceuticals

    India
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    Poddar Pharmaceuticals

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    Packaging :

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    Alprazolam

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    Approval Date :

    Application Number :

    Registration Country : India

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    08

    RELIANCE FORMULATION PVT. LTD

    India
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    RELIANCE FORMULATION PVT. LTD

    India
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    Regulatory Info :

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    Alprazolam

    Brand Name : ZOLIPAX SR 0.5

    Dosage Form : Sustained Release Tabl...

    Dosage Strength : 0.5MG

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    08

    RELIANCE FORMULATION PVT. LTD

    India
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    Not Confirmed
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    RELIANCE FORMULATION PVT. LTD

    India
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    Alprazolam

    Dosage : Sustained Release Tabl...

    Dosage Strength : 0.5MG

    Brand Name : ZOLIPAX SR 0.5

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    Registration Country : India

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    09

    Shaimil Laboratories

    India
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    Shaimil Laboratories

    India
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    Propranolol Hydrochloride; Alprazolam

    Brand Name : Alzonol-20

    Dosage Form : Tablet

    Dosage Strength : 20MG; 0.25MG

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    09

    Shaimil Laboratories

    India
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    Shaimil Laboratories

    India
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    Propranolol Hydrochloride; Alprazolam

    Dosage : Tablet

    Dosage Strength : 20MG; 0.25MG

    Brand Name : Alzonol-20

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    Application Number :

    Registration Country : India

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    10

    Vaishali Pharma Ltd

    India
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    Vaishali Pharma Ltd

    India
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    Regulatory Info :

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    Alprazolam

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    Dosage Form : Tablet

    Dosage Strength : 0.5MG

    Packaging :

    Approval Date :

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    Registration Country : India

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    10

    Vaishali Pharma Ltd

    India
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    India
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    Alprazolam

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    Registration Country : India

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    DOSAGE - TABLET;ORAL - 0.25MG

    USFDA APPLICATION NUMBER - 18276

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    DOSAGE - TABLET;ORAL - 0.5MG

    USFDA APPLICATION NUMBER - 18276

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    DOSAGE - TABLET;ORAL - 1MG

    USFDA APPLICATION NUMBER - 18276

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    DOSAGE - TABLET;ORAL - 2MG

    USFDA APPLICATION NUMBER - 18276

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 0.5M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 0.5MG

    USFDA APPLICATION NUMBER - 21434

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 1MG

    USFDA APPLICATION NUMBER - 21434

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 2MG

    USFDA APPLICATION NUMBER - 21434

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 3MG

    USFDA APPLICATION NUMBER - 21434

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    01

    Rochem International Inc

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    Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

    Brand Name : Xylitol

    Application : Chewable & Orodispersible Aids, Coating Systems & Additives, Fillers, Diluents & Binders

    Excipient Details : Xylitol is used as filler, binder & a coating agent in various oral dosage forms in both pharmaceutical and nutraceutical applications.

    Pharmacopoeia Ref : NA

    Technical Specs : NA

    Ingredient(s) : Xylitol Excipient

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    Nanjing Well Pharmaceutical

    China
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    Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

    Brand Name : Polysorbate 80

    Application : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

    Excipient Details : Polysorbate 80 is used as a plasticizer, solubilizer, emulsifier, surfactant, and suspension stabilizer. It is also used in parenteral products.

    Pharmacopoeia Ref : ChP/USP/EP/JP

    Technical Specs : NA

    Ingredient(s) : Polysorbate 80

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    Nanjing Well Pharmaceutical

    China
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    Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

    Brand Name : Propylene Glycol

    Application : Film Formers & Plasticizers, Parenteral, Thickeners and Stabilizers, Topical

    Excipient Details : Propylene glycol is used as a solvent & stabilizer in injections. It is also used in topical semi-solids & as a plasticizer in soft capsules.

    Pharmacopoeia Ref : ChP/USP/EP/JP

    Technical Specs : NA

    Ingredient(s) : Propylene Glycol

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    04

    Finar

    India
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    Valens Pharmachem

    India
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    Nanjing Bold Chemical

    China
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    07

    Zhejiang Huakang Pharmaceutical

    China
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    08

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    France
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    BASF

    Germany
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    Gangwal Chemicals

    India
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