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Synopsis

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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as:
Molecular Formula
C9H17Cl2N5O3
Molecular Weight
314.17  g/mol
InChI Key
RKSUYBCOVNCALL-NTVURLEBSA-N

Sapropterin Hydrochloride
1 2D Structure

Sapropterin Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-1H-pteridin-4-one;dihydrochloride
2.1.2 InChI
InChI=1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1
2.1.3 InChI Key
RKSUYBCOVNCALL-NTVURLEBSA-N
2.1.4 Canonical SMILES
CC(C(C1CNC2=C(N1)C(=O)N=C(N2)N)O)O.Cl.Cl
2.1.5 Isomeric SMILES
C[C@@H]([C@@H]([C@H]1CNC2=C(N1)C(=O)N=C(N2)N)O)O.Cl.Cl
2.2 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 314.17 g/mol
Molecular Formula C9H17Cl2N5O3
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass313.0708448 g/mol
Monoisotopic Mass313.0708448 g/mol
Topological Polar Surface Area132 A^2
Heavy Atom Count19
Formal Charge0
Complexity405
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3

API SUPPLIERS

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USDMF

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01

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  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Flag India
Digital Content Digital Content

GDUFA

DMF Review : Complete

Rev. Date : 2021-10-18

Pay. Date : 2021-09-28

DMF Number : 36147

Submission : 2021-07-31

Status : Active

Type : II

Biophore

02

Pharmtech & Ingredients
Not Confirmed

02

Pharmtech & Ingredients
Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 28416

Submission : 2014-06-20

Status : Active

Type : II

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03

Dipharma Sa

Italy

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Dipharma Sa

Italy
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GDUFA

DMF Review : Complete

Rev. Date : 2014-03-04

Pay. Date : 2013-09-23

DMF Number : 26682

Submission : 2012-12-06

Status : Active

Type : II

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04

Dipharma Sa

Switzerland

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Dipharma Sa

Switzerland
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GDUFA

DMF Review : Complete

Rev. Date : 2020-08-26

Pay. Date : 2020-06-15

DMF Number : 34926

Submission : 2020-06-17

Status : Active

Type : II

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05

Honour Lab Ltd

India

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05

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GDUFA

DMF Review : Complete

Rev. Date : 2019-09-20

Pay. Date : 2019-07-26

DMF Number : 33928

Submission : 2019-08-06

Status : Active

Type : II

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06

Innopharmax Inc

Taiwan

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GDUFA

DMF Review : Complete

Rev. Date : 2020-06-23

Pay. Date : 2019-03-22

DMF Number : 33553

Submission : 2019-02-19

Status : Active

Type : II

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API Reference Price

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11-Jan-2021
30-Jul-2024
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