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ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF, 5 NDC API, $ API Reference Price

1 API Suppliers
1 USDMF
5 NDC API
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers, 1 FDA Orange Book, 2 Europe

3 FDF Dossiers
1 FDA Orange Book
2 Europe

RELATED EXCIPIENT COMPANIES

3 SPI Pharma, 6 DKSH, 2 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 8 Gangwal Healthcare, 1 Pfanstiehl, 4 ACG Worldwide, 1 Actylis, 3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 9 BASF, 1 DFE Pharma, 2 Gangwal Chemicals, 3 Ingredion Pharma Solutions, 1 Kerry, 3 Lonza Capsugel, 1 Microlex e.U, 1 Novo Excipients, 2 Pharmatrans-Sanaq, 2 Pluviaendo, 1 Prachin Chemical, 1 Qualicaps, 10 Roquette, 1 Seppic, 1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Sigachi Industries, 1 Ulanqab Kema New Material, 1 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

27 Fillers, Diluents & Binders, 15 Direct Compression, 15 Disintegrants & Superdisintegrants, 10 Thickeners and Stabilizers, 8 Empty Capsules, 8 Coating Systems & Additives, 7 Granulation, 7 Co-Processed Excipients, 7 Solubilizers, 5 Taste Masking, 5 Controlled & Modified Release, 3 Chewable & Orodispersible Aids, 3 Parenteral, 3 Film Formers & Plasticizers, 2 Coloring Agents, 1 Lubricants & Glidants

excipientsByApplications
27 Fillers, Diluents & Binders
15 Direct Compression
15 Disintegrants & Superdisintegrants
10 Thickeners and Stabilizers
8 Empty Capsules
8 Coating Systems & Additives
7 Granulation
7 Co-Processed Excipients
7 Solubilizers
5 Taste Masking
5 Controlled & Modified Release
3 Chewable & Orodispersible Aids
3 Parenteral
3 Film Formers & Plasticizers
2 Coloring Agents
1 Lubricants & Glidants

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow

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1 DATA COMPILATION #PharmaFlow

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 6,405

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

71 RELATED EXCIPIENT COMPANIES

126EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 2418-14-6, Dimercaptosuccinic acid, 2,3-bis(sulfanyl)butanedioic acid, Suximer, 2,3-dimercaptobutanedioic acid, Butanedioic acid, 2,3-dimercapto-

Molecular Formula

C₄H₆O₄S₂

Molecular Weight

182.2 g/mol

InChI Key

ACTRVOBWPAIOHC-UHFFFAOYSA-N

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.

1 2D Structure

Succimer

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2,3-bis(sulfanyl)butanedioic acid

2.1.2 InChI

InChI=1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)

2.1.3 InChI Key

ACTRVOBWPAIOHC-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C(C(C(=O)O)S)(C(=O)O)S

2.2 Synonyms

2.2.1 MeSH Synonyms

1. 2,3 Dimercaptosuccinic Acid

2. Acid, 2,3-dimercaptosuccinic

3. Acid, Dimercaptosuccinic

4. Acid, Meso-dimercaptosuccinic

5. Butanedioic Acid, 2,3-dimercapto-, (r*,s*)-isomer

6. Chemet

7. Dimercaptosuccinate, Tin

8. Dimercaptosuccinic Acid

9. Dipotassium Salt Succimer

10. Disodium Salt Succimer

11. Dmsa

12. Meso Dimercaptosuccinic Acid

13. Meso-dimercaptosuccinic Acid

14. Monosodium Salt Succimer

15. Rhenium Salt Succimer

16. Ro 1 7977

17. Ro-1-7977

18. Ro17977

19. Succicaptal

20. Succimer

21. Succimer Antimony Sodium Salt, (r*,s*)-isomer

22. Succimer, (r*,r*)-(+,-)-isomer

23. Succimer, Dipotassium Salt

24. Succimer, Disodium Salt

25. Succimer, Monosodium Salt

26. Succimer, Rhenium Salt

27. Succimer, Tin Salt

28. Tin Dimercaptosuccinate

29. Tin Salt Succimer

2.2.2 Depositor-Supplied Synonyms

1. 2418-14-6

2. Dimercaptosuccinic Acid

3. 2,3-bis(sulfanyl)butanedioic Acid

4. Suximer

5. 2,3-dimercaptobutanedioic Acid

6. Butanedioic Acid, 2,3-dimercapto-

7. Dimercaptosuccinicacid

8. Dmsa

9. 2,2-dimercaptosuccinic Acid

10. Dimercaptosuccinic Acid;dmsa

11. Mls001076671

12. Smr000499575

13. Dimercatposuccinic Acid

14. Nsc16866

15. Succinic Acid, 2,3-dimercapto-

16. 3-03-00-01033 (beilstein Handbook Reference)

17. Einecs 219-334-5

18. Nsc 259951

19. Brn 1725149

20. Unii-4s9ju7xf01

21. 2,3-dimercapto-succinic Acid

22. Imercaptosuccinic Acid

23. Cid_9354

24. 2,3-disulfanylsuccinic Acid

25. Succinic Acid,3-dimercapto-

26. Schembl14942

27. Mls001332563

28. Mls001332564

29. Chembl28721

30. Meso-2,3-dithiosuccinic Acid

31. 2,3-disulfanylbutanedioic Acid

32. Butanedioic Acid,3-dimercapto-

33. 2,3-disulfanylsuccinic Acid #

34. 4s9ju7xf01

35. Bdbm60868

36. Dtxsid10859324

37. Meso 2,3-dimercaptosuccinic Acid

38. Nsc259951

39. Mpi Dmsa Kidney Reagent (salt/mix)

40. Akos006228463

41. .alpha.,.beta.-dimercaptosuccinic Acid

42. Db14089

43. Nsc-259951

44. Ls-12987

45. Nci60_001347

46. A4995

47. Ft-0628241

48. Ft-0695306

49. 18d146

50. Q56604713

2.3 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₄H₆O₄S₂
Molecular Weight	182.2 g/mol
XLogP3	0.1
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	181.97075102 g/mol
Monoisotopic Mass	181.97075102 g/mol
Topological Polar Surface Area	76.6 Å²
Heavy Atom Count	10
Formal Charge	0
Complexity	139
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Mpi dmsa kidney reagent
Active Ingredient	Technetium tc-99m succimer kit
Dosage Form	Injectable
Route	Injection
Strength	n/a
Market Status	Prescription
Company	Ge Healthcare

2 of 2
Drug Name	Mpi dmsa kidney reagent
Active Ingredient	Technetium tc-99m succimer kit
Dosage Form	Injectable
Route	Injection
Strength	n/a
Market Status	Prescription
Company	Ge Healthcare

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Antidotes

Agents counteracting or neutralizing the action of POISONS. (See all compounds classified as Antidotes.)

Chelating Agents

Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)

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API Reference Price

[{"dataSource":"API Export","activeIngredients":"SUCCIMER","year":"2021","qtr":"Q1","strtotime":1609785000,"product":"FCI 3351 (SUCCIMER) PACKING (BATCH NO.SI M\/M00120)","address":"","city":"","supplier":"PIRAMAL PHARMA SOLUTIONS","supplierCountry":"INDIA","foreign_port":"PHILADELPHIA METROP","customer":"LANNETT","customerCountry":"UNITED STATES","quantity":"10.98","actualQuantity":"10.98","unit":"KGS","unitRateFc":"5599.9","totalValueFC":"62255","currency":"USD","unitRateINR":414675,"date":"05-Jan-2021","totalValueINR":"4553131.5","totalValueInUsd":"62255","indian_port":"HYDERABAD AIR","hs_no":"29309099","bill_no":"7685649","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"","customerAddress":""},{"dataSource":"API Export","activeIngredients":"SUCCIMER","year":"2021","qtr":"Q1","strtotime":1612117800,"product":"FCI 3351 (SUCCIMER) PACKING (BATCH NO.SI M\/M00420)","address":"","city":"","supplier":"PIRAMAL PHARMA SOLUTIONS","supplierCountry":"INDIA","foreign_port":"PHILADELPHIA METROP","customer":"LANNETT","customerCountry":"UNITED STATES","quantity":"15.89","actualQuantity":"15.89","unit":"KGS","unitRateFc":"5704","totalValueFC":"89693.9","currency":"USD","unitRateINR":410970,"date":"01-Feb-2021","totalValueINR":"6530313.3","totalValueInUsd":"89693.9","indian_port":"HYDERABAD AIR","hs_no":"29309099","bill_no":"8318079","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709231400,"product":"FCI 3351 (SUCCIMER) PACKING (BATCH NO:SIM\/M00123 AND SIM\/M00124) (AS PER INVOICEAND PACKING LIST)","address":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK","city":"KURLA, MUMBAI","supplier":"PIRAMAL PHARMA SOLUTIONS","supplierCountry":"INDIA","foreign_port":"CHICAGO, IL","customer":"LANNETT COMPANY, INC.","customerCountry":"UNITED STATES","quantity":"33.37","actualQuantity":"33.37","unit":"KGS","unitRateFc":"6500","totalValueFC":"214721.8","currency":"USD","unitRateINR":534300,"date":"01-Mar-2024","totalValueINR":"17829591","totalValueInUsd":"214721.8","indian_port":"Hyderabad Air","hs_no":"29309099","bill_no":"7974418","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK, KURLA, MUMBAI","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667932200,"product":"SUCCIMER (DMSA) (CAS NO#304-55-2#)","address":"77 RATNA JYOT INDS PRMS,IRLA GAWTH AN LANE VILE PARLE WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JINAN SHENGQI PHARMACEUTICAL CO, LTD","supplierCountry":"CHINA","foreign_port":"NA","customer":"LIVEALTH BIOPHARMA PRIVATE ","customerCountry":"INDIA","quantity":"0.05","actualQuantity":"0.05","unit":"KGS","unitRateFc":"1500","totalValueFC":"77","currency":"USD","unitRateINR":"125700","date":"09-Nov-2022","totalValueINR":"6285","totalValueInUsd":"77","indian_port":"BOMBAY AIR","hs_no":"29309099","bill_no":"3237209","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"77 RATNA JYOT INDS PRMS,IRLA GAWTH AN LANE VILE PARLE WEST"}]

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Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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Europe

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Fillers, Diluents & Binders

Direct Compression

Disintegrants & Superdisintegrants

Thickeners and Stabilizers

Empty Capsules

Coating Systems & Additives

Granulation

Co-Processed Excipients

Solubilizers

Taste Masking

Controlled & Modified Release

Chewable & Orodispersible Aids

Parenteral

Film Formers & Plasticizers

Coloring Agents

Lubricants & Glidants

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CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers

1 USDMF

5 NDC API

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers

1 FDA Orange Book

2 Europe

RELATED EXCIPIENT COMPANIES

3 SPI Pharma

6 DKSH

2 Faran Shimi Pharmaceutical

1 Boai NKY Pharmaceuticals Ltd

8 Gangwal Healthcare

1 Pfanstiehl

4 ACG Worldwide

1 Actylis

3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

9 BASF

1 DFE Pharma

2 Gangwal Chemicals

3 Ingredion Pharma Solutions

1 Kerry

3 Lonza Capsugel

1 Microlex e.U

1 Novo Excipients

2 Pharmatrans-Sanaq

2 Pluviaendo

1 Prachin Chemical

1 Qualicaps

10 Roquette

1 Seppic

1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Sigachi Industries

1 Ulanqab Kema New Material

1 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

27 Fillers, Diluents & Binders

15 Direct Compression

15 Disintegrants & Superdisintegrants

10 Thickeners and Stabilizers

8 Empty Capsules

8 Coating Systems & Additives

7 Granulation

7 Co-Processed Excipients

7 Solubilizers

5 Taste Masking

5 Controlled & Modified Release

3 Chewable & Orodispersible Aids

3 Parenteral

3 Film Formers & Plasticizers

2 Coloring Agents

1 Lubricants & Glidants

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 6,405

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

GLOBAL SALES INFORMATION

71 RELATED EXCIPIENT COMPANIES

126EXCIPIENTS BY APPLICATIONS

Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)